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Best NR (Nicotinamide Riboside) Supplement in 2024

NR or nicotinamide riboside supplements are gaining popularity as another longevity product acting similarly to NMN (nicotinamide mononucleotide). NR supplements are suggested to replenish NAD+ levels in the body and support healthy aging.

However, the question remains — how to find the best NR supplements on the market, abundant with various formulations? For this reason, we conducted market research and selected 6 NR products that, in our opinion, stand out in quality.

Best NR supplement: shortlist

  1. GenuinePurityTM — best NR supplement with improved bioavailability
  2. Tru Niagen® — best overall NR supplement for longevity
  3. PartiQlar — best price for NR supplement
  4. Elysium — best nicotinamide riboside for liver
  5. ProHealth — best NR and TMG supplement
  6. VitalityPRO — top-quality UK brand of NR

How to select the best nicotinamide riboside supplement in 2024?

To select the best NR supplement in 2024, we considered the following quality criteria.

Third-party tested
ManufacturingPrice per serving
Increased NR bioavailabilityPurity and safetycGMP facilities$0.80–2.00
  • Formulation. When picking the best NR products, we considered what measures were taken to enhance the bioavailability of NR supplements.
  • Third-party testing. Although this is not mandatory for supplement brands, manufacturers aiming to ensure their product’s purity and safety should display third-party testing conducted by independent labs.
  • Manufacturing. Another quality and safety measure is the manufacturing of the supplements in advanced facilities that follow cGMP standards for developing contaminant-free products.
  • Price per serving. NR products on our list are reasonably priced depending on the formulation and doses. The price per serving is the range of your spending on your daily NR consumption.

What is NR?

NR, or nicotinamide riboside, is a form of vitamin B3 that has gained popularity for its potential health benefits and proposed anti-aging effects. NR is suggested to convert into nicotinamide adenine dinucleotide (NAD+) in the body, which is a critical molecule involved in energy production, DNA repair, cellular health, and more.

Although research about NR is warranted, the available evidence suggests the effects of this agent in various health aspects, such as supporting metabolic and cellular function, liver health, and the potential to reduce blood pressure. Keep in mind that the long-term benefits of nicotinamide riboside have yet to be established with clinical research.

In summary, NR shows promise as a molecule that may help slow the aging processes. Despite the encouraging evidence, it is important to consult your healthcare provider before starting any NR supplement.

How to choose the right product for you?

To ensure you are buying a quality NR supplement to meet your health needs, you should pay close attention to the following factors when analyzing the market:

  • Purity. Make sure to check the purity indication of the nicotinamide riboside supplement made by the provider on the official website. NR supplements are preferred to have more than 95% purity.
  • Ingredients. Check additional ingredients that might play a synergistic role with NR to enhance your healthspan. Besides, read the supplement label to ensure it’s free from GMOs, and in case of intolerances — soy, gluten, nuts, and GMOs.
  • Customer reviews. Read customer feedback on review platforms or the product page to learn about the company’s approach to delivery, customer support, product packaging, and overall brand reputation.
  • Dosage per serving. Supplements used in higher doses may pose a risk of severe side effects. Therefore, select products incorporating ingredients in safe doses for daily consumption.

Best NR supplements in 2024: overview

In this section, you will gain detailed information about our pick of the best NR supplements. Here, we discuss the products’ certification, quality testing results, purity, and price.

Read on to choose the best product that may suit your needs and accompany you in your longevity journey.

1. GenuinePurity™ — best NR supplement with improved bioavailability

Genuine Purity™ Nicotinamide Riboside

Amazon — 4.3 ⭐⭐⭐

GenuinePurityTM goes beyond mere ingredient selection, prioritizing both safe doses and absorption in their NR supplement. Utilizing clinically tested nicotinamide riboside in optimal amounts, they enhance bioavailability through liposomes derived from sunflower lecithin.

According to the provider and the research it references, NR faces absorption challenges in stomach acids. By encapsulating it in liposomal capsules, the manufacturer aims to protect the compound, aiding its utilization in the bloodstream.

GenuinePurityTM provides 2 Certificates of Analysis (COA) — one confirming the supplement content matches label claims and the other verifying the absence of contaminants and heavy metals.

According to the third-party lab tests, this supplement from GenuinePurityTM contains 95.50% nicotinamide riboside. We like the brand’s transparency regarding scientific findings about NR, its effects on the body, as well as consumption recommendations.

Adults are recommended to take 2 daily capsules of GenuinePurityTM NR delivering 300 mg of the compound. Notably, the manufacturer offers a 97-day full-money-back guarantee, enabling you to test the supplement and return it if you don't experience the promised effects.

A one-time purchase of GenuinePurityTM NR is $69.95 ($2.33 per serving). If you are interested in investing in a long-term supplementation, choose the brand's 3 or 6-month supplies for substantial discounts.

What users like about GenuinePurity™

Based on Amazon reviews from GenuinePurityTM customers, here are the main positive aspects highlighted:

  • Liposomal formula
  • Manufacturing standards
  • Potential health benefits
  • Easy-to-swallow capsules

What users don’t like about GenuinePurity™

Although positive reviews are superior, there are customers reporting negative experiences or aspects of GenuinePurityTM NR:

  • Higher price
  • No detailed information on the label
  • Insufficient company information on the web

Company review

GenuinePurity™ is a supplement created by Leading Edge Health, a reputable health-focused brand based in Canada that serves customers in over 130 countries.

Leading Edge Health focuses on enhancing overall well-being through natural ingredients and formulations. The company’s product line includes supplements for anti-aging, cognitive function, sexual health, and general wellness.

Our verdict about GenuinePurity™

Based on our review, customer feedback, and company reputation, GenuinePurityTM stands out as one of the leading brands in the NR market. The product itself is praised for being produced in facilities following high-quality standards and being formulated according to available scientific evidence.

The liposomal formula, which is proposed to improve the molecule's bioavailability, is another plus for people looking for quality NR supplements.

2. Tru Niagen® — best overall NR supplement on the market

Tru Niagen age better nad

Amazon — 4.4 ⭐⭐⭐⭐
Trustpilot — 3.6 ⭐⭐⭐⭐
Official website — 4.3 ⭐⭐⭐

Tru Niagen® is one of the best NR supplements on the market, produced as a flagship product incorporating clinically tested safe and effective NIAGEN® nicotinamide riboside.

ChromaDex, the manufacturer of the NR ingredient, conducted a clinical trial where NIAGEN® was observed to increase NAD+ levels by 50% after a short-term supplementation.

The brand is NSF-certified for sports (National Sanitation Foundation). This is a reputable third-party organization assessing the safety and purity of dietary supplements.

Tru Niagen® offers a versatile choice of servings per bottle of encapsulated NR.

Our pick of the best option for servings per bottle would be the bottle containing 90 capsules for 3 month's supply. With 1 capsule serving daily, you will receive 300 mg NR.

This option of Tru Niagen® NR supplement is sold at $119.95 ($1.33 per serving).

What users like about Tru Niagen®

We analyzed the customer feedback of Tru Niagen® across the brand’s official website, Amazon, and Trustpilot, and here are the key aspects that users appreciate about the product:

  • Significant energy improvements
  • Fast delivery
  • Quality packaging
  • Scientific backing

What users don’t like about Tru Niagen®

Here are the main aspects users report not liking about Tru Niagen® and its NR product:

  • Allergic reactions
  • Comparably higher priced
  • Issues with returns

Company review

Tru Niagen®, developed by ChromaDex, stands out as a leader in the NAD+ supplement market, supported by robust scientific backing and endorsements from Nobel Prize-winning scientists.

ChromaDex's commitment to scientific evidence is evident in over 300 published studies and regulatory approvals. With an emphasis on transparency and quality, Tru Niagen® aims to enhance cellular health and vitality, making it a trusted choice for those prioritizing longevity and well-being.

Our verdict about Tru Niagen®

Tru Niagen® is considered a leader specializing in creating NR supplements based on rigorous scientific research. The brand’s numerous certificates underline its commitment to production safety, transparency, and purity standards.Based on the brand’s claims, clinical findings, and customer reviews, Tru Niagen® may be a great choice for individuals looking for enhanced energy levels and focus, and potential skin improvements.

3. PartiQlar — best price for NR supplement per serving size

partiQlar Pure Nicotinamide Riboside NR

Trustpilot — 4.5 ⭐⭐⭐⭐⭐
Official website — 5.0 ⭐⭐⭐⭐⭐

PartiQlar offers a reasonable price for serving size for its Pure NR supplement. Moreover, the provider offers significant discounts with multi-buy options for more prolonged consumption.

The raw ingredient in PartiQlar is sourced from Effepharm, which is a reliable supplier of NMN and NR molecules. The provider claims nicotinamide riboside to be 98% pure.

The products are developed in cGMP-certified and FDA-compliant manufacturing facilities. PartiQlar Pure NR is also NSF-certified for sport, vegan, and free from artificial colors, allergens, and GMOs.

The provider recommends taking 1 capsule a day to receive 350 mg NR. Although the supplement label does not include information about NR form, the third-party testing indicates the use of nicotinamide riboside chloride.

You can order your 2-month supply of PartiQlar Pure at $47.99 ($0.80 per serving).

What users like about partiQlar

Although as a newly established company with a limited number of customer reviews compared to other brands, we have identified unbiased opinions of what users like about partiQlar NR:

  • Timely delivery
  • Helpful customer service
  • Comparably lower price

What users don’t like about partiQlar

Some customers mentioned the following issues with partiQlar:

  • Unexpected custom fees
  • Slow shipment for international orders
  • Technical issues with the website

Company review

Despite being a newly established company, partiQlar is rapidly distinguishing itself in the longevity supplement market by prioritizing transparency and customer satisfaction.

Specializing in high-quality supplements like Resveratrol, TMG, and others, partiQlar ensures each product meets stringent standards through rigorous third-party testing and adherence to FDA and NSF guidelines. Their commitment to sourcing from trusted suppliers and providing detailed product information underscores their dedication to quality.

Our verdict about partiQlar

For those looking for a high-quality NR supplement made in the EU, partiQlar may be the best choice. The brand has a strong commitment to sourcing high-purity ingredients from trusted suppliers like Effepharm and adhering to manufacturing standards, including FDA and NSF certifications.

According to the majority of positive customer reviews, you may also enjoy the brand’s aim to provide fast delivery and excellent customer service.

4. Elysium — best nicotinamide riboside formula for liver health


Amazon — 4.0 ⭐⭐⭐⭐
Trustpilot — 3.8 ⭐⭐⭐⭐
Official website — 4.3 ⭐⭐⭐⭐

Elysium Basis is a formula of pterostilbene (PT) and nicotinamide riboside (NR-E). The combination has been tested in a clinical trial and shown well-tolerated during 6-month supplementation in people with non-alcoholic fatty liver disease. It was also associated with reduced inflammatory markers in the liver.

The manufacturer included nicotinamide riboside crystalline in the supplement as another NR form. NR-E in Basis was developed by the eminent scientists behind Elysium and is a patent-pending product.

Basis by Elysium is manufactured in cGMP-certified facilities and is certified NSF for sport. It is free from allergens and GMOs. It is also third-party tested for safety and purity.

The daily recommended dose of Basis is 2 capsules in the morning, delivering 250 mg of NR-E and 50 mg of PT.

One month's supply of Elysium Basis NR-E costs $60.00 ($2.00 per serving). The provider offers significant discounts with multi-buy options.

What users like about Elysium

Here are the highlighted aspects users like about Elysium NR and the brand:

  • Ease-to-swallow capsules
  • Well-designed packaging
  • Brand transparency about scientific findings

What users don’t like about Elysium

Based on customer feedback, here are the main issues people have with Elysium:

  • Damaged products during delivery
  • Issues with managing subscriptions
  • Concerns with customer service

Company review

Founded with a commitment to scientific findings and collaboration, Elysium utilizes insights from Nobel Prize-winning advisors and a network of over 25 world-renowned researchers. Led by co-founder Dr. Leonard Guarente, whose pioneering work on SIR2 and NAD+ laid the foundation for their flagship product Basis, Elysium continues to innovate in proactive health.

Our verdict About Elysium

For anyone searching for a reliable NR brand led by renowned scientists in the longevity field, Elysium may be an ideal candidate. Despite occasional issues with delivery and subscriptions reported by some customers, its commitment to transparency and clinical validation makes it a compelling choice for those prioritizing their well-being.

5. ProHealth — best NR and TMG supplement formula

ProHealth Nicotinamide Riboside Pro

Amazon — 4.1 ⭐⭐⭐⭐
Trustpilot — 2.6 ⭐⭐⭐
Official website — 4.2 ⭐⭐⭐⭐

ProHealth combines TMG (betaine) with NR — making it a promising supplement option for people seeking to support liver function and promote muscle formation and cellular reproduction.

ProHealth utilizes NIAGEN® nicotinamide riboside by CromaDex. The manufacturing is handled in the USA, cGMP-certified facilities. Another quality standard is the third-party testing displayed on the product page.

ProHealth NR supplements are available in 2 NR dosage amounts — 300 mg and 500 mg. TMG doses also differ in these two options — 150 mg and 250 mg, respectively.

The bottle of ProHealth nicotinamide riboside 500 mg is sold at $64.95 ($2.16 per serving). The 300 mg option is available for 30 days at $47.30 ($1.57 per serving).

What users like about ProHealth

Based on a number of customer reviews on the brand’s website and Amazon store, these are the positive aspects users like about ProHealth and its NR supplement:

  • Energy improvement
  • Trustworthy brand
  • Integrated combination of TMG and NR

What users don’t like about ProHealth

While positive reviews are predominant, we have highlighted the issues that people mention about ProHealth that they don't like:

  • Stomach discomfort
  • Partially filled capsules
  • Issues with customer service

Company review

Founded by Rich Carson out of a personal need to manage chronic illness, ProHealth has grown into a trusted name in the supplement industry over its 35-year journey. Beyond supplements, they provide cutting-edge research updates and personalized nutritional guidance.

ProHealth maintains its leadership in the wellness industry with an A+ BBB rating, underscoring its commitment to excellence in supplement production.

Our verdict about ProHealth

ProHealth’s combination of TMG and NR presents a convenient option for individuals interested in supplementing with these longevity molecules in a single capsule for potentially promoting longevity and increased energy.

Additionally, with a longstanding commitment to scientific rigor and decades of experience, ProHealth may be a reliable choice in the wellness industry.

6. VitalityPRO — top-quality UK-based brand of NR

VitalityPRO NR

Amazon — 4.5 ⭐⭐⭐⭐⭐
Trustpilot — 4.9 ⭐⭐⭐⭐⭐
Official website — 5.0 ⭐⭐⭐⭐⭐

If you are looking to buy an NR supplement made in the UK, VitalityPRO may be an ideal choice. Moreover, the brand ships to the USA, Australia, and other EU countries.

VitalityPRO is a 98.5% pure NR supplement containing no artificial colors, preservatives, or allergens. The brand utilizes stable nicotinamide riboside chloride as the only ingredient in the supplement.

Although the brand doesn't mention the source of its raw materials, the manufacturing of this NAD+ supplement takes place in cGMP-certified and ISO 9001 facilities.

VitalityPRO NR supplement contains no fillers, and the capsules are made from vegetable cellulose. The brand recommends people with no known health concerns take 1–2 capsules daily to receive 300–600 mg NR.

One bottle of VitalityPRO NR supplement costs $64.00 ($1.42 per serving). The price per serving depends on the daily consumption.

What users like about VitalityPRO

The customer reviews for VitalityPRO, though limited in number, highlight several positive aspects:

  • Sleep and energy improvements
  • Clear packaging
  • Good value for the price

What users don’t like about VitalityPRO

The customers have highlighted key areas for improvement that VitalityPRO should address:

  • Poor delivery experience
  • Lack of temperature control during delivery
  • General issues with delivery

Company review

Ideal for health-conscious individuals seeking supplements that may be both effective and environmentally responsible, VitalityPRO's biodegradable packaging underscores their dedication to sustainability.

Based in the UK, VitalityPRO is a forward-thinking company specializing in high-quality supplements. Their commitment to rigorous testing and adherence to UK ISO 9001 quality standards ensures reliability and production safety in every product.

Our verdict about VitalityPRO

VitalityPRO emerges as a compelling choice for those seeking a high-quality NR supplement crafted in the UK. Despite delayed international shipments and packaging issues, the customers like the brand’s offer of good value for the price and some potential health improvements.

Comparing the top NR supplements of 2024

BrandPrice*Price per servingServings per bottleServing sizeNR dose per servingAdditional ingredientsNR form
GenuinePurity™$69.95$2.33302 capsules300 mg-Liposomal NR
Tru Nigen®$119.95$1.33901 capsule300 mg-NR chloride (NIAGEN®)
PartiQlar$47.99$0.80601 capsule350 mg-β-NR
Elysium$60.00$2.00302 capsules250 mgPterostilbeneCrystalline NR
ProHealth$64.95$2.16302 capsules500 mgTMG (betaine)NR chloride (NIAGEN®)
VitalityPRO$64.00$1.42452 capsules600 mg-NR chloride

* — prices vary depending on the product serving size and dosage selection, and daily consumption.

Please be aware that currently, there is limited information on the safety and efficacy of NR supplements. Since it is a new molecule in the market, there is limited research in humans on the supplementation of NR in any formulations. However, it is important to note that since we are not the manufacturer, we do not take any responsibility for the proposed health claims provided by the brands, and we urge you to discuss the use of these supplements with your healthcare provider.

Conclusion: what is the best NR supplement?

In conclusion, we believe GenuinePurityTM is the best NR supplement. Our selection of this product is grounded in thorough research of the brand claims, supplement formulation, and third-party testing results displayed in the COA.

The number of positive customer reviews, timely delivery, and free delivery provided by the company are other cornerstone aspects for us when selecting the best brand from our list.

What are the benefits of NR supplements?

NR or nicotinamide riboside supplements are attracting interest for their association with enhancing NAD+ (nicotinamide adenine dinucleotide) levels.

Although the evidence comes mainly from animal or limited studies with humans, the research evolving around NR benefits suggests the following health effects:

  • Healthy metabolism. Limited evidence suggests that NR supplementation may be associated with SIRT1 gene activation. As a result, this process may trigger higher energy production and contribute to the prevention of metabolic diseases. It may also mimic caloric restriction, supporting healthy weight management, as observed in animal studies.
  • Liver support. Although the evidence emerges from mice studies and is not yet applied to humans, NR supplementation was observed to promote liver regeneration and correction of non-alcoholic fatty liver disease.
  • Reduced blood pressure. A small clinical study, expected to be finalized by the end of the year, suggests that supplementation with nicotinamide riboside may help reduce blood pressure and aortic stiffness.
  • Healthy aging. Currently, NR supplementation is related to longevity by supporting metabolism and reducing chronic inflammation — the latter being a hallmark of accelerated aging.

NR vs. NMN supplements: what is the difference?

First and foremost, it is crucial to note that NMN is no longer available as a dietary supplement due to the latest FDA investigation on whether it can be labeled as a drug. Yet, for people looking for ways to enhance NAD+ levels, NR comes as a good alternative to NMN.

Let’s discover these two molecules and how they are different.

Understanding nicotinamide riboside

NR is a naturally occurring form of vitamin B3. It has become one of the promising NAD+ precursors. Nicotinamide riboside is considered a labile molecule requiring meticulous production for stability.

NR is observed to take 2 steps to turn into NAD+. After entering the cells, it converts into NMN, which in turn becomes NAD+, increasing the latter's levels.

Currently, the scientific evidence of NR effectiveness emerges from animal studies and limited human clinical trials.

Understanding nicotinamide mononucleotide

NMN is a vitamin B3 derivative — meaning it has a slightly different molecular structure than NR. Although NMN is slightly a larger molecule, it is observed to have better stability.

However, some brands might develop liposomal NMN products, claiming to improve the bioavailability or absorption of the supplement. More to this, NMN is proposed to take one step to convert to NAD+ in the body.

Can NR supplements cause any side effects?

Although there are limited studies on NR supplementation in humans, so far, NR supplementation has not demonstrated significant side effects. Commonly, the providers recommend taking up to 500 mg NR daily, which is an amount used in studies without exposing individuals to adverse effects.

People also report feeling:

  • Nausea
  • Bloating
  • Fatugue
  • Headaches
  • Itching

Pregnant or breastfeeding women, people under 18 years of age, and individuals with known health conditions should consult with their healthcare provider before supplementing with this NAD+ precursor.

Best NR supplement worth your attention — conclusion

Despite the limited amount of scientific evidence, NR supplements are gaining popularity as NMN alternatives. Nicotinamide riboside demonstrates promising longevity properties by elevating NAD+ levels and supporting healthy aging.

NR is being widely marketed as a longevity supplement, making it challenging to find a quality product suitable for individual health needs. If you want to find the best NR supplement on the market, you should pay close attention to the supplement quality aspects.

Explore other NAD+ precursors and their benefits

Explore the best longevity supplements to help you age gracefully.

Choose your NMN supplement to support a longer healthspan.

Find your high-quality and effective NAD+ supplement in the market.

For cardiovascular support and optimal energy levels, consider choosing top TMG supplements.


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