Ever wonder why red wine was traditionally given so much praise for its health benefits? Well, what it all comes down to is resveratrol — a natural compound found in grape skins that has been suggested to support heart health and even help slow the aging process.
Now, let me be clear, resveratrol neither is nor should be considered as some sort of fountain of youth, but based on what the science tells us, this antioxidant might be worth including in your routine. And no, I don’t mean through endless glasses of wine, or munching on grapes all day — a resveratrol supplement might be a more practical option.
In this article, I’ll be talking all things resveratrol — what it is, its proposed benefits and potential side effects, the different types available, ideal dosages, and the best times to take it. I’ll also introduce six resveratrol supplements that, in my book, are among the best on the market right now based on my research.
Resveratrol best brands: shortlist
- Best non-liposomal purified trans-resveratrol: partiQlar
- Best overall trans-resveratrol supplement: GenuinePurity
- Best resveratrol supplement with co-factors: ProHealth
- Best bioavailable liposomal resveratrol: Purovitalis
- Best offer for liposomal trans-resveratrol supplement: Hello100
- Best pure resveratrol product: Luma Nutrition





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Comparison of the top 6 resveratrol supplements
Brand | Cost per bottle | Servings per bottle | Price per serving | Resveratrol form | Resveratrol content per serving | Source | Other ingredients | Our pick for |
partiQlar | $36.99 | 60 | $0.61 | Non-liposomal capsules | 500 mg | Effepharm (supplier) | None | Best non-liposomal purified trans-resveratrol |
GenuinePurity | $66.80 | 30 | $2.22 | Liposomal capsules | 500 mg | Japanese knotweed | None | Overall best trans-resveratrol supplement |
ProHealth | $31.08 | 30 | $1.03 | Non-liposomal capsules | 1000 mg | Made with yeast fermentation process | Quercetin, red wine extract, decaf green tea extract, BioPerine | Best resveratrol supplement with co-factors |
Purovitalis | $43.95 | 60 | $0.73 | Liposomal capsules | 240 mg | Japanese knotweed | None | Best bioavailable liposomal resveratrol |
Hello100 | $51.00 | 60 | $0.85 | Liposomal capsules | 250 mg | Polygonum cuspidatum | None | Best offer for liposomal trans-resveratrol supplement |
Luma Nutrition | $33.52 | 30 | $1.12 | Non-liposomal capsules | 600 mg | Not stated | None | Best pure resveratrol |
The resveratrol supplement that ranks highest on our list
After considering several strong contenders, one resveratrol supplement has risen above the rest — partiQlar. We've ranked it highest for several compelling reasons.
A leading reason is that GenuinePurity offers pure pure resveratrol product, with scientific backing.
The product also uses liposomal encapsulation technology, which may help your body absorb supplements more easily. This, in turn, may enhance the absorption of the main ingredient, resveratrol.
So, all things considered, GenuinePurity trans-resveratrol appears to meet most, if not all, criteria for a quality supplement. This well-rounded profile is why we believe it outshines the competition.
Best resveratrol supplements in 2025: product reviews
Now, let's jump right into our list of what we consider the top resveratrol supplement brands on the market today. In the following sections, we'll put each brand under the lens and review their offerings in detail. We hope this will give you a clearer understanding of what’s available and help you choose the resveratrol supplement that best fits your needs.
1. partiQlar — best non-liposomal purified trans-resveratrol

If liposomal technology isn’t your preference or you’re skeptical about its impact, but you still want a highly purified resveratrol product manufactured to high standards, we think you’ll come to appreciate partiQlar’s Pure Resveratrol.
Who would benefit
- Someone who’s looking for a highly purified form of resveratrol
- Those who prefer a non-GMO supplement without artificial additives
More about partiQlar
- Resveratrol purity exceeds 99%, verified by third-party testing
- Contains 500 mg of trans-resveratrol per serving
- Developed in the U.S. within a GMP-certified and FDA-registered production facility.
- Non-GMO and free from artificial colors and sweeteners
- Resveratrol is sourced from Effepharm, a leading supplier in the industry.
- Costs $36.99 per bottle ($0.61 per serving)
Our verdict
Given its reliable sourcing, resveratrol purity exceeding 99%, and the brand’s commitment to clean ingredients, partiQlar, in our books, is a top choice for anyone looking to support their longevity with a dependable, no-frills supplement.
2. GenuinePurity — best overall trans-resveratrol supplement

If you're in the market for a high-quality resveratrol supplement with good bioavailability and a science-backed formulation, GenuinePurity may be your pick.
Here’s a closer look at who would benefit from this product and what you need to know:
Who would benefit
- Anyone interested in supplementing with a pure resveratrol product
- Those looking for a supplement with scientific backing
More about GenuinePurity
- Resveratrol sourced from Japanese knotweed extract
- Uses liposomal technology to enhance absorption
- 500 mg of trans-resveratrol per serving
- At $66.80 per bottle ($2.22 per serving), it’s on the pricier side, but we think you’re paying for quality here
Our verdict
GenuinePurity Resveratrol offers a well-rounded profile, which includes 99% purity, strong scientific evidence supporting the formulation, and the brand's transparency in manufacturing and testing efforts to ensure and maintain quality. While it may not be the most budget-friendly supplement, the 97-day money-back guarantee and free shipping in the U.S. help offset the price. After all, you’re getting a top-tier resveratrol supplement.
3. ProHealth — Best resveratrol supplement with co-factors

Among the best resveratrol supplements out there, ProHealth is an option that simply outperforms others in terms of strength. With every serving this product delivers 1,000 mg of resveratrol and on top of that is formulated with other beneficial co-factors.
Who would benefit
- People who want a high-dose resveratrol supplement
- Those interested in additional antioxidant support from red wine extract and quercetin
More about ProHealth
- 1,000 mg of resveratrol per serving — a dose among the highest available
- Comes in a combination of red wine extract and quercetin for extra antioxidant support
- While it lacks the liposomal delivery system used by some other high-end supplements, it includes BioPerine, which may help improve the absorption of resveratrol
- Resveratrol is sourced from Veri-te® — a company providing bioavailable trans-resveratrol obtained through yeast fermentation.
- Costs $31.09 per bottle ($1.03 per serving)
Our verdict
If you're looking for a supplement that not only provides a high dose of resveratrol but also includes extra ingredients for added benefits, ProHealth is a top choice that you should not look past.
4. Purovitalis — best bioavailable liposomal resveratrol

The big selling point of Purovitalis Resveratrol is its bioavailability, which the brand makes sure to highlight in its advertising. The product uses a liposomal delivery system that encapsulates resveratrol in lipid-based particles. This design is intended to help your body absorb resveratrol better so that you receive the proposed benefits with every dose.
Who would benefit
- People seeking a supplement with enhanced absorption
- Those looking for a product that pairs well with other supplements, like NMN
More about Purovitalis
- Liposomal delivery system
- Produced in an FDA-registered and GMP-certified facility
- Subjected to third-party testing
- Each serving delivers 240 mg of resveratrol sourced from Japanese knotweed
- Costs $43 per bottle ($0.73 per serving)
Our verdict
We think Purovitalis Resveratrol is one of the top options available. Its liposomal delivery system and overall quality — which we think should be largely attributed to credible manufacturing and testing practices — make it a supplement definitely worth trying.
5. Hello100 — best offer for liposomal trans-resveratrol supplement

Hello100 is perfect for those looking to make their money go further. With big savings on multibuy deals, it's an attractive pick for anyone interested in long-term use without a hefty price tag.
Who would benefit
- Those looking specifically for a liposomal trans-resveratrol product
- People who intend to supplement with resveratrol and want to stack up in advance
More about Hello100
- Resveratrol sourced from Polygonum cuspidatum — a natural source
- Each Hello100 capsule provides 250 mg of trans-resveratrol
- Made in the U.S. in FDA-registered, GMP, and HACCP-compliant facilities
- Third-party tested
- Original price is $51.00 per bottle ($0.85 per serving). When purchasing three bottles, the cost per bottle drops to $39.66. When buying six bottles, the price per bottle further decreases to $33.16
Our verdict
Hello100 impresses with more than just its liposomal form and natural resveratrol origins — it also has great multibuy deals. This combination makes it a practical choice for anyone looking to commit to long-term resveratrol use.
6. Luma Nutrition — best pure resveratrol with minimal added ingredients

If you prefer a straightforward resveratrol supplement that's highly pure and delivers a solid dose, Luma Nutrition will fit the bill just fine. It’s perfect for those who want a supplement with just the essentials.
Here’s a closer look at Luma Nutrition:
Who would benefit
- Anyone looking for a pure resveratrol supplement without co-factors
- People after a high-dose resveratrol product
More about Luma Nutrition
- Resveratrol purity of 98%
- 600 mg of resveratrol content per serving, higher than most other products on the market
- Third-party tested for label accuracy
- Marketed to support various health aspects, including immune function, cardiovascular health, and skin radiance
- Costs $33.52 per bottle ($1.12 per serving)
Our verdict
When searching for a pure, high-dose resveratrol supplement, Luma Nutrition, in our opinion, is a hidden gem. It’s third-party tested, and the price is easy on the wallet.
Our criteria for choosing the best resveratrol supplements in 2025
We made sure to consider these key aspects to give you a full picture of the top-rated choices out there.
Resveratrol quantity | Bioavailability | Purity and quality | Source |
Concentration in line with scientific evidence | Whether the brand has taken measures to increase bioavailability | Minimal fillers | Natural sources |
- Resveratrol quantity. Since the scientific backing is paramount, we looked into the quantity of resveratrol, which is in line with the ones used in clinical trials.
- Bioavailability. Some brands use specialized formulations or delivery methods, such as liposomal encapsulation, to improve the absorption of resveratrol. We checked for them as well.
- Purity and quality. Minimal fillers, no unrelated additives, and no contaminants are essential for a clean product. We focused on finding supplements that meet these criteria and looked for confirmation through third-party testing reports.
- Source. The source of resveratrol can influence its quality and price. Natural sources like Japanese knotweed or grape seed extract are typically preferred over synthetic options. However, synthetic resveratrol should not be a show-stopper either.
How to choose a resveratrol supplement?
When searching for the best resveratrol supplement, branding and initial appeal aren't everything. Not all resveratrol supplements have the same formulation or profile, and as a result, they may not serve the same purposes. If you're looking for a high-quality product that meets your specific needs, there are key quality markers to consider. To help you, we’ve put together a list of important factors to look for when selecting the best resveratrol supplement for you.
- Bioavailability. The body's ability to absorb and utilize resveratrol is crucial for its effectiveness. Supplements labeled as liposomal or those containing ingredients like black pepper extract are good indicators of a quality formulation designed for increased absorption.
- Manufacturing. Those resveratrol supplements that are manufactured in FDA-approved and cGMP-certified facilities should be preferred always. This type of manufacturing sticks to the highest quality standards eliminating the possible content of contaminants in the final product.
- Safety. Third-party testing is one method for documenting the quality of resveratrol supplements. This is an independent lab test to examine the ingredients in the capsule, their purity, and whether the facts on the supplement label correspond to the capsule content.
- Price per serving. Choose resveratrol supplements within your daily budget. Although it's a valuable antioxidant for your health, the price should not exceed $0.50–$2.50 per serving. Compare product prices for a more affordable choice.
Where to buy resveratrol supplements
Resveratrol supplements are available to purchase worldwide. You can find these supplements online and in some physical drugstores as well.
Keep in mind that in some cases, you may be charged with extra customs taxes or VAT depending on the country you are residing in.
If you are looking for the best resveratrol options in Australia, refer to our dedicated article.
What is resveratrol?
Resveratrol is a naturally occurring polyphenol compound found in various plants. Polyphenols have several roles in plants, e.g., protection from pathogens.
In supplements, resveratrol is primarily used for its antioxidant and anti-inflammatory properties. It has been studied for its role in promoting heart health by improving endothelial function and reducing oxidative stress.
It is proposed to work by scavenging free radicals and modulating various cellular pathways. Resveratrol has been found to inhibit the activity of certain proteins which play a role in inflammation and pain.
This antioxidant may also support brain function and exhibit anti-aging effects. However, more research is needed to confirm these benefits.
Personal insights from a nutrition enthusiast
Resveratrol is a polyphenol compound with antioxidant and anti-inflammatory properties, and it’s been suggested to have potential benefits for heart health, cognitive function, and healthy aging. That being said, the amounts of resveratrol found in food sources like red wine or grapes are relatively small. The proposed benefits observed in clinical studies were typically associated with resveratrol administered in more concentrated forms, such as pure compounds or extracts, and at higher doses. To realistically access these potential effects, supplements offer a more practical option.
And so, to give you a clearer picture of what it’s like to supplement with resveratrol and what to look for in a quality product, we reached out to Amy Brangwyn, a medical research writer and nutrition enthusiast, who shared her insights with us.
Which resveratrol supplement should you go for?

It’s clear to me that not all supplements are made the same, and honestly, that’s even more true when a compound like resveratrol starts trending in the health world. That’s why I think it’s so important to choose a well-reviewed product, recommended by healthcare practitioners, and third-party lab tested to make sure there aren’t any so-called ‘nasties’ hiding in the ingredients list.
I use resveratrol myself, and I personally prefer products that include other beneficial co-factors, such as those that may have been clinically studied to improve absorption. But I think it really comes down to your own personal preferences. If you like having a host of other beneficial compounds in your supplement, then go for one packed with co-factors. But if you want it straight up, then I’d recommend going for the highest-purity liposomal product.
Personal favorites
I feel like ProHealth has to be mentioned when we are talking about some of the best resveratrol supplement brands out there. Their formula includes resveratrol, quercetin, red wine extract, bioperine, and green tea extract. It's third-party lab tested and produced in FDA-regulated, GMP-certified facilities in the U.S. — details that really add a layer of trust in a market that can sometimes feel oversaturated.
Also, personally, I don’t mind the slightly larger capsule size, but I know this can be an issue for some people. If you know you find pills hard to swallow, then another option worth checking out would be Hello100. I have come across a lot of customer reviews praising how easy their capsules are to take. Plus, their product is liposomal, meaning the resveratrol is delivered via tiny fat particles designed to help your body better absorb it.
Benefits of resveratrol supplements
Thanks to their antioxidant and anti-inflammatory properties, resveratrol supplements may provide several potential health benefits. Below we take a closer look at some of the more prominent benefits.
Heart health
Resveratrol may help improve endothelial function and reduce oxidative stress, thus promoting overall cardiovascular health. Endothelial function is essential for blood pressure regulation and blood vessel protection. Free radicals, which are elevated during oxidative stress, contribute to the development of atherosclerosis, which may result in complications such as stroke. Antioxidants like trans-resveratrol are key players in reducing free radical levels, thereby contributing to heart health.
Blood sugar regulation
Oxidative stress and inflammation may lead to impaired insulin sensitivity, which might cause higher blood sugar levels. Resveratrol may improve insulin sensitivity and help regulate blood sugar levels.
Brain health
Resveratrol may enhance cerebral blood flow and support cognitive performance. Oxidative stress in the brain and neuronal damage may lead to cognitive decline. By activating the SIRT1 protein, resveratrol might help reduce the accumulation of reactive oxygen species, potentially aiding in these neurological health issues.
Yet, these results are emerging mostly from animal studies and more research is needed to observe the same effects in humans.
Slow aging
Resveratrol’s activation of sirtuins is associated with anti-aging effects. Additionally, the combination of NMN and resveratrol may offer neuroprotective benefits, including improved working and spatial learning memory.
Studies in animals suggest that resveratrol supplementation combined with exercise may prevent age-associated muscle loss.
Reduced inflammation
Resveratrol's numerous health benefits are attributed to its anti-inflammatory and antioxidant properties. It is proposed to work by inhibiting pro-inflammatory factors and preventing the accumulation of reactive oxygen species.
Side effects associated with taking resveratrol supplements?
Studies in humans have shown that both resveratrol and trans-resveratrol supplementation are likely well tolerated in healthy individuals with only minor side effects related to the gastrointestinal system. Supplement brands generally recommend 250 to 1000 mg daily.
Moreover, resveratrol may interact with certain medications, potentially increasing the risk of bleeding or altering the drug's effectiveness. Resveratrol, which may act as a blood-thinning agent, should also be avoided before surgery.
Keep in mind that studies on the possible side effects of resveratrol are still limited, so more evidence is needed to fully understand possible hazards.
Types of resveratrol
Naturally occurring resveratrol consists of cis-resveratrol and trans-resveratrol, with each form exhibiting different biological activities.
Trans-resveratrol
Trans-resveratrol is the most extensively researched and commonly used form in supplements due to its higher bioavailability and stability. Trans-resveratrol has been demonstrated to have antioxidant and anti-inflammatory properties, making it the preferred choice.
Cis-resveratrol
Cis-resveratrol is less biologically active than its counterpart and has not been studied as extensively. For these reasons, cis-resveratrol is not typically used in resveratrol supplements.
Resveratrol derivatives
Resveratrol derivatives are modified forms of the compound with different bioavailability, stability, or biological activity. Examples include pterostilbene, which is naturally found in blueberries and grapes, and piceatannol, found in passion fruit.
Resveratrol dosage: how much should I take?
The dosage of resveratrol supplements varies based on individual needs, goals, and health status. Clinical studies have used a wide range of dosages, from as low as 10 mg to as high as 5,000 mg per day.
There is currently no established daily recommended intake for resveratrol, and the long-term effects of taking high doses are not yet fully understood. Therefore, it is essential to consult a healthcare professional before starting resveratrol supplementation.
Remember that the potential health benefits of resveratrol can also be obtained through a balanced diet rich in fruits and vegetables, particularly those containing resveratrol, like red grapes and berries.
The best time of day to take resveratrol supplements
There currently is no definitive consensus on the best time to take resveratrol supplements, as research in this area is limited. While some brands recommend taking resveratrol on an empty stomach early in the morning, studies suggest that it may be better absorbed when taken with a meal, particularly one containing some fat, as this may improve the compound's bioavailability.
FAQ
Is resveratrol good for blood?
Yes. Resveratrol may positively affect blood vessels and circulation by promoting vasodilation and improving endothelial function, thereby benefiting cardiovascular health.
What is the best resveratrol supplement to take?
ProHealth. Based on our research, the best resveratrol supplement to take is ProHealth. This supplement offers a strong dose of resveratrol — 1,000 mg. It also combines quercetin and red wine extract to enhance antioxidant support.
Is resveratrol effective in skincare?
It may be. Resveratrol in skincare may improve various skin concerns, such as aging skin, and can be used both topically and orally. It is suggested to have anti-aging, anti-inflammatory, antioxidant (UV protective), and antimicrobial properties. However, the evidence is still emerging.
Is 500 mg of resveratrol enough?
Yes. A daily dose of 500 mg may provide benefits, but individual responses can vary. Since the optimal dose of resveratrol is not well-established, clinical trials have used a wide range of doses.
What is the most bioavailable form of resveratrol?
To be determined. Trans-resveratrol is considered more bioavailable than cis-resveratrol. Certain formulas or delivery strategies, such as liposomal encapsulation or micronization, may enhance the absorption and bioavailability of resveratrol. However, we still lack sufficient studies to determine the best form of resveratrol.
10 resources
- Nature Reviews Drug Discovery. Therapeutic potential of resveratrol: the in vivo evidence.
- Nature. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan.
- British Journal of Pharmacology. Antioxidant effects of resveratrol in the cardiovascular system.
- NPJ Precision Oncology. The therapeutic potential of resveratrol: a review of clinical trials.
- Cell. Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases.
- Cell Metabolism. Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans.
- Mayo Clinic Proceedings. Alcohol and cardiovascular health: the dose makes the poison… or the remedy.
- Cancer Research. Repeat dose study of the cancer chemopreventive agent resveratrol in healthy volunteers: safety, pharmacokinetics, and effect on the insulin-like growth factor axis.
- PloS one. A molecular mechanism for direct sirtuin activation by resveratrol.
- Biomedicines. Resveratrol: A Double-Edged Sword in Health Benefits.
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