While we can't reverse the aging process, we can take proactive measures to help mitigate its effects. This includes making adjustments to our diet and lifestyle choices, and for some — considering anti-aging supplements.
One such anti-aging supplement is NMN, which is a precursor to NAD+ — an essential-to-life molecule involved in numerous cellular activities.
This GenuinePurity™ review delves into the supplement's formulation, its proposed mechanism of action, and the potential benefits it may offer, all aimed at giving you a broader understanding of this product.
Your well-being is our top priority. Our in-house Research team and expert fact-checkers diligently review every content piece, ensuring you receive accurate, safe, and up-to-date health information to support your health decisions. Get an inside look at our thorough testing framework.
What is GenuinePurity™ NMN?
GenuinePurity™ NMN is an anti-aging product developed by a Canadian-based brand, Leading Edge Health. It contains one active ingredient, NMN, in a research-evaluated dose per serving, 250 mg.
While manufacturers do not promise immediate anti-aging effects in the short term, they claim this supplement may help you retain youthfulness in the long run due to the potential increase of NAD+ levels. Emerging preliminary studies also suggest that potential NMN benefits may include brain, skin, and heart health support. Although most of these findings are derived from animal or cell studies, NMN is gaining attraction in the longevity community, with GenuinePurity™ standing as a valuable option to consider.
Harness the benefits of youthfulness with an evidence-backed 250 mg NMN dosage from GenuinePurity™.
What makes the brand stand out is its approach to the bioavailability of NMN. GenuinePurity™ aims to improve the bioavailability of this product by using a liposomal compound delivery method. This method encapsulates NMN in liposomes, potentially shielding the compound from stomach acid as well as supporting its absorption. Theoretically, this delivery method is suggested to help increase NMN bioavailability and help transfer more of it to systemic circulation.
Key benefits of GenuinePurity™ NMN
NMN is proposed to support your overall health and longevity by increasing NAD+ levels. NAD+ is involved in a wide range of body functions and its levels are suggested to decline as we age, therefore increasing its levels is proposed to yield various benefits, some of which may not be directly observed by the users.
Below, we analyzed a few benefits highlighted by the brand.
Increased energy production
As NAD+ depletion is linked to cellular energy decline, increasing the levels of this compound may contribute to increased energy.
Some clinical trials also suggest this to be the case. For instance, one study concluded that NMN supplementation may boost aerobic capacity, theorizing this effect is possible due to improved oxygen utilization.
Another clinical trial demonstrated that NMN may improve physical endurance as seen from the six-minute walking test used to determine NMN's impact on healthy middle-aged individuals.
May support metabolic health
GenuinePurity™ also highlights metabolism support as one of the benefits of taking NMN. Several human trials are linked to this potential benefit in the context of blood sugar control, lipid profiles, and body composition.
For instance, one clinical study reported that NMN contributed to an increase in muscle insulin sensitivity and insulin signaling in women with prediabetes and overweight. Another study on middle-aged and older adults has shown that NMN may prevent worsening insulin resistance.
For lipid profiles and body composition, there are two similar studies suggesting NMN to be beneficial. One of these studies included 16 postmenopausal women, while another one involved 30 middle-aged and older individuals who were considered to be either overweight or obese. During both trials, individuals taking NMN experienced improvements in their cholesterol profiles and showed enhanced weight regulation.
May support cardiovascular health
Besides potential improvements in cholesterol levels, some studies on NMN reported other factors that may be considered to be beneficial for heart health.
For instance, during the study on individuals with obesity or overweight, participants reported lower diastolic blood pressure levels after taking NMN. In another trial, healthy middle-aged subjects in the NMN group were reported to have their arterial stiffness decrease — yet, this particular study did not find a significant difference compared to the placebo group.
Other benefits proposed by the brand
GenuinePurity™ mentions a wide range of other benefits associated with NMN. However, these benefits have not been examined in clinical trials, thus, it is hard to evaluate them from a scientific view. Examples of these include:
- Joint health support
- Cognitive support
- Increase in libido
- Improvement of mood
- Improvement of sleep quality
Remember that NMN is still largely understudied, and it is possible that you may not feel any noticeable effects. You can opt for a blood test of NAD+ levels before and after to assess the product’s impact on it.
GenuinePurity™ NMN ingredients and dosage
GenuinePurity™ Liposomal NMN contains only one active ingredient — β-nicotinamide mononucleotide (β-NMN). This is a naturally occurring and active form of NMN generally used in supplements.
To formulate the product, the manufacturer included other inactive ingredients.
| Ingredient | Amount per capsule | Suggested benefits |
| NMN | 250 mg | DNA repair, cellular, heart, brain, bone, and muscle health, better metabolism |
| Vegetable cellulose | N/A | Keeps the capsule vegan, supports efficient bioactive compound delivery |
| Phospholipid complex | N/A | Making up liposomes to support NMN bioavailability |
| Vegetable stearate | N/A | Used as an anticaking agent |
NMN is the key ingredient in this supplement, proposed to provide certain anti-aging effects. Other ingredients are used only to create the supplement.
User reviews and testimonials
Trustpilot — 4.3 ⭐⭐⭐⭐
At the moment, the reviews for GenuinePurity™ NMN are rather scarce, making it hard to identify definitive trends in user feedback. Our team has gathered some of the available testimonials to give you insight into possible advantages and disadvantages associated with the product.
What people liked
A few customers on Trustpilot mentioned an increase in energy levels after taking NMN. Other reviews expressed satisfaction with delivery time and customer service.
Leading Edge Health, the parent company behind this product, has received mostly positive feedback online, with reviewers highlighting the quality of their products. Moreover, people express gratitude for fast and efficient customer support.
What people didn’t like
Some negative feedback for Leading Edge Health is related to logistics, including slow delivery times or lost packages. In addition, some individuals claimed they had issues with receiving refunds. Lastly, individuals not based in the U.S. mentioned issues with customs, marking the need to pay import fees.
What experts say about GenuinePurity™ Liposomal NMN
To gain expert insights on GenuinePurity Liposomal NMN, we consulted with Sazan Sylejmani, PharmD, Pharmacist in Charge at Westmont Pharmacy. Although he has not personally used the product, his professional experience provides valuable guidance for evaluating supplements.
Sylejmani notes that the supplement industry in the U.S. is less regulated, leading to varying quality between brands. He emphasizes, “NMN shows promise as an anti-aging supplement in early research, but many questions remain about optimal doses, long-term effects, and differences between delivery methods like capsules vs. liposomal formulas. More research is needed.”
For those considering GenuinePurity™ or similar products, Sylejmani advises being wary of unrealistic health claims and ‘miracle’ ingredients. He stresses, “Do thorough research on the company, manufacturing standards, and ingredients before purchasing any supplement. Look for brands with transparent, high-quality standards that follow good manufacturing practices. Be wary of misleading marketing claims.”
While Sylejmani cannot fully evaluate GenuinePurity™ products without firsthand knowledge of their manufacturing processes, he encourages consumers to exercise caution and prioritize transparency and quality when choosing supplements.
Tips and tricks for best results with GenuinePurity™ NMN
GenuinePurity™ recommends taking 1 capsule daily. You can take it with any meal of the day. With one daily serving, you will receive 250 mg of NMN — a dose reported to be well tolerated in current human studies.
Another reason the provider offers this serving size is that its NMN is protected with liposomes. According to them, a significant amount of non-liposomal NMN gets destroyed in the acidic environment in your stomach.
Thus, higher doses may be needed with ordinary NMN to ensure your body receives at least some of it. GenuinePurity™ believes that with liposomal formula you can be guaranteed to receive the amount indicated on the label. However, thus far, these brand claims have never been evaluated in relevant studies, and there is still a lack of research on how NMN — liposomal or not — is absorbed and processed in the human body.
Side effects of GenuinePurity™ NMN
While GenuinePurity™ Liposomal NMN supplement has never been subject to clinical research, its main ingredient NMN has been previously reported to be generally well tolerated when consumed in doses up to 1,250 mg for up to 4 weeks. However, as with other supplements, more evidence is needed, particularly on its long-term health effects, and misuse may lead to adverse health concerns.
This supplement is formulated with a dose evaluated in multiple scientific studies — 250 mg of NMN. A placebo-controlled trial showed that with higher than 250 mg of NMN, some of the adverse events among a few participants were reported to be:
- Rashes on the skin
- Tingling or numbness
- General weakness
- Slurred speech
- Fever
It is important to consult a doctor before incorporating NMN into your wellness routine, particularly if you are pregnant, taking other supplements or medications, or have a pre-existing condition.
How much does GenuinePurity™ NMN cost and where to buy It?
GenuinePurity™ sells its Liposomal NMN at an affordable price as well as offers discounts when buying multiple bottles.
| Bottle | Price after discount |
| 1 bottle | $69.00 |
| 3 bottles | $195.00 |
| 6 bottles | $354.00 |
One bottle of GenuinePurity™ NMN contains 60 capsules, and if you follow the daily recommended doses, this is enough for a 2-month supply. The provider advises you to order 3 bottles for significant savings on your 6-month journey.
Moreover, the brand offers a 97-day full money-back guarantee if you are unsatisfied with the purchase. Note that the prices may vary depending on the chosen currency.
Free shipping of GenuinePurity™ Liposomal NMN is granted for domestic orders in the U.S. The shipping prices may vary for international orders depending on the destination country and shipping method. It offers affordable shipping to Canada, Australia, and the UK.
The shipping prices will be deducted after you place an order and fill in your shipping information.
Comparison: GenuinePurity™ NMN vs other popular alternatives
| Brand | Price | Price per serving | Serving size | Servings per bottle | Additional ingredients |
| GenuinePurityTM | $69.00 | $1.15 | 1 capsule | 60 | None |
| Omre NMN + Resveratrol | $59.97 | $1.99 | 2 capsules | 30 | Resveratrol, BioPerine® |
| ProHealth | $73.50 | $2.45 | 3 capsules | 30 | Resveratrol, TMG |
| partiQlar | $79.99 | $1.33 | 1 capsule | 60 | None |
| Purovitalis | $115.0 | $1.91 | 2 capsules | 60 | None |
How and why we chose to review GenuinePurity™ NMN
With biohackers like David Sinclair praising NMN for its anti-aging potential, this compound is regarded as one of the most sought-after in the longevity community. GenuinePurity™ stands out as a brand offering some of the best NMN on the market. Below, we highlighted a few factors that our team appreciated.
Manufacturing
The product is manufactured in Current Good Manufacturing Practice (cGMP)-certified facilities that adhere to strict guidelines. As per the brand, they are located in the U.S. and are regularly inspected by the FDA.
Third-party tested
Third-party testing is one of the crucial factors that buyers should be aware of before jumping into purchasing NMN products.
GenuinePurity™ NMN is third-party tested with certifications available on their official website. The testing demonstrates a 96% purity of NMN, accurately reflecting the label. Moreover, GenuinePurity™ is also analyzed for heavy metals and microbiological profiles and is confirmed to be free from these contaminations.
Liposomal delivery
Bioavailability is an important factor to consider when selecting NMN products. NMN is not lipid soluble and, thus, is hypothesized to be poorly absorbed, especially compared to both water and fat-soluble substances.
Aiming to improve absorption, brands use various manufacturing processes. Although no studies have been conducted to confirm that liposomal delivery is superior to traditional forms, it theoretically may have a positive impact on bioavailability as NMN is surrounded by liposomes that may help protect it from stomach acid. This method is also applied by GenuinePurity™ in an attempt to enhance absorption, making it a valuable option in the NMN market.
Final verdict: is GenuinePurity™ NMN worth it?
If you are opting for NMN supplementation, GenuinePurity™ NMN stands out as one of the budget-friendly options. Moreover, the brand uses an innovative delivery system (liposomes) in an attempt to enhance NMN’s absorption. To confirm the claimed 96% purity, GenuinePurity™ NMN is third-party tested with the Certificate of Authenticity readily available on the website. The product is also tested for possible contaminations.
FAQ
What is NMN, and how does it work?
NMN is a precursor to NAD+, an important compound for various cellular processes. As we age, our bodies naturally produce less NAD+. NMN supplements may increase NAD+ levels and, thus, are believed to have potential anti-aging properties.
How long does it take to see results from GenuinePurity™ NMN?
The brand mentions that you may expect the first subtle results after 2 weeks of supplementation. Keep in mind that the effects observed and the time you may notice them can also differ from person to person
Is GenuinePurity™ NMN safe for long-term use?
Long-term data on NMN safety is limited. As of now, most clinical trials on NMN in humans lasted between 4 and 24 weeks.
Does GenuinePurity™ NMN have any side effects?
Yes, GenuinePurity™ NMN may have side effects, including skin rashes, tingling sensation, numbness, weakness, slurred speech, and fever. If you are experiencing any of these or other side effects, please discontinue taking the supplement and consult your healthcare provider.
How does GenuinePurity™ NMN compare to other anti-aging supplements?
GenuinePurity™ NMN could be considered to be one of the budget-friendlier alternatives in the NMN market. Moreover, it is third-party tested with the certificates readily available on their official website.
6 resources
- Journal of the International Society of Sports Nutrition. Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study.
- GeroScience. The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial.
- Science. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women.
- Frontiers in Aging. A Multicentre, Randomised, Double Blind, Parallel Design, Placebo Controlled Study to Evaluate the Efficacy and Safety of Uthever (NMN Supplement), an Orally Administered Supplementation in Middle Aged and Older Adults.
- Glycative Stress Research. Clinical evaluation of changes in biomarkers by oral intake of NMN.
- The Journal of Clinical Endocrinology & Metabolism. Nicotinamide Adenine Dinucleotide Augmentation in Overweight or Obese Middle-Aged and Older Adults: A Physiologic Study.
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