Is NMN Good For People with Diabetes?

Diabetes Mellitus is a clinical syndrome of the endocrine system, and over the years, it has only been managed under the strict supervision of insulin therapy or oral hypoglycemic agents. However, there are ongoing research studies about how supplements such as NMN can control diabetes. Is this realistic?

Key takeaways:
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    NMN has been proven to be good in mice with type-2 diabetes but with no evidence to prove its benefits in diabetic humans.
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    A balanced diet, insulin therapy, or oral hypoglycemic agents are the recommended treatment methods for diabetes.
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    Type-2 diabetes is the most prevalent type of diabetes, affecting both the young and old.

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Can a condition that has affected 422 million of the world’s population and caused 1.5 million deaths yearly be easily treated with NMN? This article reviews in detail what you need to know about diabetes and whether or not NMN is a good treatment plan for it as a supplement.

Diabetes – everything you need to know

Diabetes is a chronic metabolic disease characterized by hyperglycemia due to deficiency or diminished effectiveness of insulin. Diabetes mellitus is the most common disturbance of carbohydrate metabolism. Absolute or relative lack of insulin affects the metabolism of carbohydrates, protein, fats, water, electrolytes, and insulin with grave consequences. The long-standing metabolic disorder is often associated with functional and structural changes in body cells, and blood vessels, which are permanent and irreversible.

These changes lead, in turn, to the development of well-defined clinical entities referred to as complications of diabetes mellitus, which characteristically affect the eye, kidney, heart, blood vessels, and nervous system.

Types, causes, and complications of diabetes

Diabetes could be:

Insulin-dependent diabetes mellitus is also known as Type 1 DM or IDDM.

Non-insulin-dependent diabetes mellitus is also known as Type-2 DM or NIDDM.

Diabetes mellitus is secondary to the treatment of other conditions with recognizable pathological processes.

The most common type is Type-2 Diabetes mellitus: approximately 90-95% of more than 37 million Americans have type-2 diabetes. It is commonly developed in people over 45 years of age, with more recorded cases in children, teens, and young adults.

Some of the causes of diabetes mellitus include:

  • Impaired glucose metabolism;
  • Viral and genetic factors;
  • Obesity;
  • Insulin antagonists;
  • Some drugs, notably corticosteroids and thiazide diuretics;
  • Liver diseases.

If not detected early or well managed, some complications may arise from this metabolic disorder. These include:

  • Loss of motor and sensory sensations;
  • Lowered resistance to infection;
  • Persistent urinary tract infections;
  • Pneumonia;
  • Cataract and blindness;
  • Diabetic gangrene;
  • Hypertension;
  • Myocardial infarction;
  • Atherosclerosis;
  • Diabetic acidosis etc.

Now that you understand what diabetes is and how severe it can be, let's look into whether NMN can be good for diabetes.

Are NMN supplements good for diabetes?

Nicotinamide mononucleotide (NMN) is a molecule that is involved in the metabolism of energy in cells and has been the subject of some scientific research as a potential treatment for various health conditions, including diabetes. However, more research is needed to determine the safety and effectiveness of NMN for the treatment of diabetes or any other health condition.

It is important to note that NMN is not approved by the Food and Drug Administration (FDA) for the treatment of any health condition and should not be used as a substitute for approved medical therapies. If you have diabetes or any other health condition and are considering taking NMN or any other dietary supplement, it is important to speak with your healthcare provider to discuss the potential risks and benefits. They can help you make an informed decision about whether NMN is appropriate for you and can recommend the appropriate treatment plan.

A study suggests that NMN may have potential benefits for people with diabetes, this is because the underlying metabolic pathways influenced by NMN are similar in mice and humans. According to this study, it was also found that NMN may help to improve insulin sensitivity and reduce blood sugar levels in animals. However, it is important to note that most of this research has been conducted in animal models and more research is needed to determine the effects of NMN on insulin sensitivity and blood sugar levels in humans.

It's fascinating to contemplate whether a substance that can be naturally found in the body will be a good option for treating diabetes. This curiosity has led to much ongoing research yet to be conclusive about its use in humans but only in mice. Regardless of the similarity in these two organisms, do not make yourself a lab rat by using an NMN supplement if you have diabetes hoping it would work for you just as it did in the little mice. Instead, stick to the recommended treatment methods.

The goal of management in diabetes is directed toward achieving a normal metabolic state and prevention of complications that generally accompany diabetes. The principles of treatment include the removal of symptoms, correction of hyperglycemia and glycosuria, as well as the attainment and maintenance of healthy body weight.

The three treatments methods for DM include:

Strict balanced diet alone

The diet of a diabetic patient should be individualized based on the type of diabetes, possible complications, cultural and socio-economic factors, and principles of good nutrition. The diet should contain a balance of carbohydrates, protein, and fat. Calorie intake should provide for optimal growth and development; obese diabetic patients should be given reduced calories to bring about gradual and steady loss of weight. Food should also be eaten at regular intervals throughout the day.

Diet and oral hypoglycemic drugs

Oral antidiabetic drugs are commonly used when only dietary management fails to give satisfactory results.

Diet and insulin therapy

This is the best treatment indicated for all insulin-dependent diabetics. With insulin therapy, increased blood glucose levels can be kept within reasonable limits. It should be taken subcutaneously or intravenously but not orally as it is readily destroyed in the GIT.

In addition, moderate exercise and health education about diabetes are also essential. It's only right to consult your physician if you have diabetes rather than resort to supplements. Let your healthcare provider be a part of your decision-making process in choosing the best diabetic treatment method that suits your health. Your strict adherence to the treatment plan, drug regimen, and recommended exercise is a jump start to living healthy with diabetes.

No scientific research is presented to prove that NMN supplements are suitable for people with diabetes. However, a series of research has acknowledged the benefits of this supplement in laboratory diabetic mice. While there are doubts and uncertainty about the safety and effectiveness of NMN in humans, it's only best to stick to the appropriate treatment methods for diabetes mellitus as recommended by a healthcare provider.


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