NMN Supplements Are Banned in USA, Can NAD Injections Replace Those?

The NMN supplement has been banned, but here is an alternative. Let's find out why and how NAD+ injections may be a good alternative.

Key takeaways:
  • arrow-right
    NMN is a precursor to NAD+, i.e. it is needed in the body to produce NAD. However, it can be replaced through NAD+ therapy.
  • arrow-right
    Neither NAD nor NMN can reverse aging; they can contribute significantly to your well-being as you age.
  • arrow-right
    NAD can safely replace NMN.

Following the recent development of the popular longevity supplement ingredient beta-nicotinamide mononucleotide (β-NMN) being banned as a supplement, many people might begin to look for alternative supplements.

Since NAD intravenous injection/drips (NAD-IV) offers a similar effect as NMN supplements, replacing the latter with the former is now being considered. Here, you’ll learn the benefits of NAD, how it works, and if it can safely replace NMN.

Why were NMN supplements banned?

The Food and Drug Administration (FDA) recently announced the withdrawal of the New Dietary Ingredients (NDI) status of NMN, which has resulted in a series of debates in the pharmaceutical industry. According to the FDA, the reason for this withdrawal was that NMN “has been authorized for investigation as a new drug.” As such, it can no longer be sold as a supplement.

This new development was a reversal of the agency’s previous decision that allowed the sale of NMN as a new dietary supplement. However, this latest announcement is yet to be enforced and NNM supplements like Hello100 are still available for purchase.

What is NAD?

Nicotinamide adenine dinucleotide (NAD) is a naturally occurring coenzyme of vitamin B-3 (niacin) responsible for energy production in the body cells. This coenzyme is crucial for metabolic activities, including converting food into energy and DNA repair. Its function is vital for the immune system.

Nourishing the body at the cellular level can significantly contribute to one’s health — and an excellent way to achieve this is through NAD-IV.

The science behind NAD-IV therapy

NAD-IV therapy is usually administered slowly into the bloodstream via intravenous (IV) drip. This administration method will make its absorption into the bloodstream easier and faster. Without the NAD coenzyme, your cell might be unable to perform its function correctly. According to a published study, your body’s level of NAD declines as you age, causing low cellular action. Consequently, you’ll have low energy and be unable to carry out your daily activities as much as you used to when you were younger.

As NAD is infused into your bloodstream, the NAD molecule immediately binds with the proteins in your body to create the active enzymes that will catalyze the rate of cellular metabolism. This will revitalize and energize your cells, making you feel more youthful and energetic.

NMN vs. NAD: how they compare

NMN and NAD+ are both essential in energy production in the body. They’re different molecules, though; NMN and NAD+ have many chemical elements in common. However, our body needs NMN to create NAD+, so when you have one, you have the other.

Neither of these two molecules can reverse aging, they can contribute significantly to your well-being as you age.

Can NAD injections replace NMN?

NMN may be gone, but NAD+ injections can help the body's cells meet the body's requirement of NAD while retaining the benefits of NMN and more. Hence, NAD injections can safely replace NMN.

NAD+ injection can help supplement the declining NAD in the body by promoting the uncomplicated and smooth absorption of NAD+ in the bloodstream rather than in the digestive system. Thus, giving the body the maximum benefits of NMN without actually taking NMN. So, if you are a taker of NMN supplements, here is an alternative. With NAD+ injection, you can improve your overall well-being and vitality.

NAD+ injection is a promising therapy for tackling age-related conditions and slowing down the effects of the aging process. Still it is worth to know that NAD+ molecule is bigger than NMN. After NAD-IV, when NAD+ molecule goes near the cell, it becomes a bit complicated to go inside the cell. Then NAD disassemble to smaller particles and these go through the cell membrane. Inside the cell these smaller particles connect to the NAD complex completely. In comparison - NMN do to have these kind of difficulties and raise NAD+ levels more easily.

What are the benefits of replacing NMN with NAD+ injections

An article published in Harvard Health Publishing explained some of the benefits of NAD+ injection, including:

Management of pain and chronic conditions

NAD+ injection has both physical and psychological benefits to the body. It helps in relieving and managing pain by reducing inflammation and activating antioxidants. Asides from reducing chronic pain, it can also help reduce the side effects of diabetes. It also helps increase serotonin levels in the body and is considered a good mood stabilizer, especially for depression and anxiety.

Helps in weight management

As we grow and age, our body’s metabolic processes slow down and result in fat accumulation or uneven distribution. NAD+ in the body helps produce ATP (Adenosine Triphosphate) that helps convert the chemical energy in the food we eat to fuel other body functions. If NAD+ in the body is deficient, this may not be possible; however, NAD+ injection or therapy accompanied by a good diet regimen can help maintain a healthy body weight by stimulating more ATP production. More ATP means good metabolic function.

Boosts energy

While converting chemical energy from food to fuel, NAD+ therapy helps boost your energy. Because of their significant role in ATP production, they help; increase energy levels, and reduce fatigue and exhaustion. If, after a long flight, NAD+ injections can help reduce the side effects of jet lag.

Help boost cognitive function

Cognitive function declines with aging, and older adults experience symptoms such as brain fog, memory loss, and difficulty concentrating. At this aging stage, the body’s NAD+ also declines, which may aggravate the symptoms of age-related cognitive degeneration. NAD+ helps convert glucose into metabolic energy that supplies the brain cells; imagine what happens without NAD+. NAD+ injections can help prevent further complications by reducing neuroinflammation and enhancing mental clarity.

Enhances overall well-being

NAD+ injection helps rejuvenate and revitalize your body cells and boost energy levels; these are keys to a healthy life. Combined with a healthy diet and exercise, it works magic in maintaining a healthy body weight. All these and more are why people choose NAD+ injections over other supplements. If you want to live a healthier and more fulfilled life, consider NAD+ therapy.

NAD+ injections disadvantages

  • For NAD-IV therapy you need a minimum one hour when the drip works.
  • During NAD-IV therapy, you could feel a bit of dizziness.
  • It is not clear how often you should repeat NAD-IV.

The bottom line

NAD+ injections are a suitable replacement for NMN. They contain the same molecules, but NAD+ has more metabolic, physiological, and psychological benefits with mild to no risk of side effects. NAD+ injection or therapy is an advanced modern supplement; you can live healthier lives without an NMN supplement. Still, the NMN could be banned temporarily and after a couple of months or a year, it could get back to the stores.


Leave a comment

Your email address will not be published. Required fields are marked  


David Jordan David Jordan
prefix 1 month ago
For what it's worth and factually, NMN HAS NOT BEEN BANNED. (I'm sorry, I don't like the use all caps in online posts, and almost never use them, however this one time they seemed stylistically necessary.) I looked just now at a couple online providers and see it's still available for purchase.

What has happened so far is that one pharmaceutical company has made a request that may lead to NMN being prohibited for sale as a supplement and the FDA has issued a couple of statements. What certainly will happen in the near future is that the US supplement industry will resist and may file suit against the FDA to continue NMN's availability as a legal supplement (and not requiring a prescription). Reliable sources state the US supplement is already in communication with the FDA on this issue. The supplement industry has compelling logic to support its position.
Healthnews Team Healthnews Team
prefix 1 month ago
On October 11, the FDA informed the company Inner Mongolia Kingdomway Pharmaceutical Limited that its dietary supplement containing nicotinamide mononucleotide (NMN) could not be marketed as a dietary supplement or food. According to the preclusion provision of Section 201(ff) of the Federal, Food, Drug, and Cosmetic Act, also known as the drug preclusion clause, ingredients cannot be sold as dietary supplements if they were first approved or clinically studied as drugs.

The expert says that companies continuing to do so may be subject to fines https://healthnews.com/longevity/longevity-supplements/are-nmn-supplements-still-on-sale-in-the-u-s/
Dovid kaleky Dovid kaleky
prefix 1 month ago
Lopsided article. How about giving the recent study on mice for cancer causing of Nad? This site is not to be trusted with half the facts.
Healthnews Team Healthnews Team
prefix 1 month ago
Thank you for your comment. We recently published an article on possible NMN links to cancer. You can read the article here: https://healthnews.com/longevity/longevity-supplements/can-nmn-supplements-cause-cancer/
Please let us know if we missed any recent studies on this topic.
Joe Joe
prefix 1 month ago
NMN has not been banned in the US. The original FDA statement is under review.
David Cross David Cross
prefix 1 month ago
Having personally benefited from readily available nicotinamide riboside (TruNiagen) for the last eight years, I am curious why one would choose to take injections of NAD+ over an available oral supplement such as nicotinamide riboside which would have the effect of raising NAD+ at much lower cost. Help me to understand.