Polycystic Ovary Syndrome Linked to Increased Mortality Risk

Research presented at the Endocrine Society's annual meeting found that women with polycystic ovary syndrome have a higher risk of death at a younger age than those without the condition.

Polycystic ovary syndrome (PCOS) is a hormonal disorder that impacts one in 10 females of childbearing age. The condition causes symptoms such as irregular periods, ovarian cysts, hair growth on the face, and weight gain due to an imbalance of hormones. It's also one of the most common causes of infertility.

Moreover, individuals with PCOS are at higher risk for health issues like diabetes, depression, and endometrial cancer. And according to new research, PCOS may also increase the risk of early mortality.

The research, presented on June 15 at ENDO 2023 by Terhi Piltonen, M.D., Ph.D., from the University of Oulu and the Oulu University Hospital in Oulu, Finland, found that women with PCOS had a 47% increased risk of overall mortality than females without the disorder.

These findings resulted from a study involving 9,839 women with PCOS from the Finnish Care Register for Health Care and 70,705 females without the condition.

The scientists examined the participant's health records from 1969 to 2019 and found that women with PCOS had an increased risk of mortality due to tumors, endocrine, nutrition, metabolic conditions, and cardiovascular diseases. They were also more likely to die younger than the control group.

Piltonen says, "PCOS is a severe lifelong syndrome that increases mortality. More emphasis should be targeted on the prevention and treatment of diabetes, circulatory diseases, tumors, and respiratory diseases in women with PCOS to reduce the mortality risk."

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