NMN (nicotinamide mononucleotide) has become a popular compound for increasing levels of the so-called “youth molecule” — NAD+ (nicotinamide adenine dinucleotide). Even though NMN is no longer primarily marketed as a dietary supplement in the U.S. — as it is under investigation as a new drug ingredient — you can still find plenty of it available on the market.
Given NMN's popularity, which is largely driven by its proposed link to promoting longevity, there’s no shortage of options out there. But how do you pick a product that truly delivers over one that just claims to?
To save you the trouble, I have gone through more than a dozen NMN supplements and identified what I think are the seven best ones. I have ranked them based on specific criteria and highlighted what each one excels at, so you can pick the one that matches your preferences and needs, without all the guesswork.
Best NMN supplement: shortlist
- Best overall NMN supplement: partiQlar
- Best liposomal NMN supplement: GenuinePurityTM
- Best absorption: Hello100
- Best high-dose NMN capsules: ProHealth
- Best NMN supplement with resveratrol: Omre
- Best pure NMN product: Purovitalis
- Best NMN with protected compound delivery: Wonderfeel
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Comparison of the best NMN supplements in 2025
| Product | Serving size | Servings per bottle | Cost per bottle | Cost per serving | Dosage per serving | Form | Additional ingredients | Purity |
| partiQlar | 1 capsule per day | 60 | $79.99 | $1.33 | 500 mg | Non-liposomal capsule | - | 99.00% |
| GenuinePurityTM | 1 capsule per day | 60 | $79.95 | $1.33 | 250 mg | Liposomal, capsule | - | 96.00% |
| Hello100 | 1 capsule per day | 60 | $84.00 | $1.40 | 250 mg | Liposomal, capsule | - | 99.50% |
| ProHealth | 2 capsules per day | 30 | $58.00 | $1.93 | 500 mg | Non-liposomal, capsule | - | not specified |
| Omre | 2 capsules per day | 60 | $59.97 | $2.00 | 500 mg | Non-liposomal capsule | Resveratrol, BioPerine® | 98.00% |
| Purovitalis | 2 capsules per day | 30 | $60.00 | $2 | 250 mg | Liposomal, capsule | - | 99.00% |
| Wonderfeel | 2 capsules per day | 30 | $88.00 | $2.93 | 900 mg | Non-liposomal, capsule | Ergothioneine, trans-resveratrol, hydroxytyrosol, vitamin D3 | 99.00% |
What is the best NMN product based on our review?
After reviewing seven brands, we have selected partiQlar to be the best NMN product on our list. Our selection of this brand is based on the quality provided, the brand transparency, the product availability in the U.S., price.
The brands' product stands out with its vegetarian formula and clean label, meaning that it contains no binders or magnesium stearate, unlike many other options. The company also discloses information about the current scientific findings behind NMN, usage guidelines, and doses.
NMN best brands in 2025
In curating our top-rated brands and best NMN supplement reviews listed below, we meticulously evaluated attempts to increase NMN bioavailability, product pricing, quality, customer trust, and formulation to ensure careful consideration of all technical aspects.
1. partiQlar Pure NMN
Notable for providing supplements with potential health benefits, partiQlar is also known for its dedication to transparency and quality. The company provides various longevity supplements using ingredients sourced from trusted suppliers globally.
The product stands out due to its clean label and vegetarian formula, free from binders or magnesium stearate, which are common in other products. Each capsule contains 500 mg of 99% pure NMN, with a recommended dosage of 1 capsule daily.
Pure NMN by partiQlar undergoes third-party testing and is produced in U.S.-based, FDA, and NSF-registered facilities following cGMP standards.
The price for partiQlar Pure NMN starts at $79.99 for a two-month supply, with 60 capsules per bottle. The brand also offers bulk purchase promotions and additional discounts for monthly and yearly subscriptions.
Main ingredients
- β-nicotinamide mononucleotide
Key features of partiQlar Pure NMN
- Purity: 99%.
- Amount of NMN: 500 mg.
- Additional ingredients: None.
- Our pick for: Best NMN for increased energy.
Moreover, partiQlar receives praise for its high-quality, third-party-tested NMN, prompt shipping, and excellent customer service.
Company review
The supplement company based in Lithuania, EU, is dedicated to offering high-quality longevity supplements, including TMG, resveratrol, and berberine, alongside NMN and NR.
The company sources its ingredients from top suppliers, ensuring the compounds are produced in cGMP-certified and FDA-inspected facilities. To promote transparency, partiQlar displays third-party lab test results for each product and features both positive and negative customer reviews.
2. GenuinePurity™ Liposomal NMN
GenuinePurity™ Liposomal NMN, developed by the Canadian brand Leading Edge Health, has served customers in over 130 countries for over 20 years. Named the best NMN product of 2024, it features NMN using advanced liposomal technology aimed at increasing compound’s bioavailability.
The product's formula includes 96% pure NMN as its sole ingredient, offering a dose of 250 mg per capsule. This design is aimed at simplifying supplement intake, reducing the need for multiple daily capsules.
Manufactured in cGMP-certified facilities, GenuinePurity™ Liposomal NMN aims to ensure high quality and production safety standards. It is free from major allergens, preservatives, and GMOs, while also making it suitable for various dietary preferences, including vegans and vegetarians.
Each bottle contains 60 servings and is priced at $79.95, with an option to pay in four interest-free installments. The additional 67-day money-back guarantee makes it a valuable investment for people seeing a convenient way to support healthy aging.
Main ingredients
- β-Nicotinamide mononucleotide
Key features of GenuinePurity™ NMN
- NMN purity: 96%.
- Amount of NMN: 250 mg.
- Additional ingredients: None.
- Our pick for: Best NMN supplement overall.
Company review
Leading Edge Health, the manufacturing company of GenuinePurityTM Liposomal NMN, is well-regarded and trusted by customers. With decades of experience in the supplement market, the brand provides a variety of products ranging from skincare to supplements for athletes and male sexual health.
3. Hello100 Liposomal NMN
Hello100's NMN formulation is distinguished by its high purity of 99.5%, designed to support well-being and address aging-related concerns. To overcome the challenge of low bioavailability due to the acidic environment of the stomach and low compound absorption, Hello100 incorporates advanced liposomal technology for its NMN product.
Despite being a relatively new player in the longevity market, Hello100 has quickly established itself as a reliable provider of NMN products. Alongside NMN, Hello100 offers Liposomal Resveratrol, which they claim can enhance healthspan and NAD+ levels when used in conjunction with NMN.
Each daily capsule provides 250 mg of NMN and is both vegan and produced in the U.S., reflecting the company's commitment to high-quality sourcing and manufacturing standards.
The brand is transparent about its quality assurance practices, displaying the COA on its website, which confirms that Hello100 Liposomal NMN is third-party tested and free from heavy metals and toxins. It is also manufactured in facilities that are compliant with cGMP and FDA regulations.
Hello100 offers a 60-day money-back guarantee, allowing users to return the product for a full refund if it does not meet their expectations. A single bottle is priced at $84, with additional options of three bottles for $252 and six bottles for $504 available on the website.
Main ingredients
- β-nicotinamide mononucleotide
Key features of Hello100 Liposomal NMN
- Purity: 99.5%.
- Amount of NMN: 250 mg.
- Additional ingredients: None.
- Our pick for: Best novel technology in an NMN product.
Company review
Founded in 2021, Hello100 is a young life science company based in Lithuania. Currently, the company specializes in manufacturing NMN and Resveratrol products, which are aimed at fighting aging and supporting a healthy lifespan.
Ingredients are sourced from around the globe to design the final products in U.S.-based facilities with rigorous quality standards.
Hello100 distinguishes itself through its focus on bioavailability and educational resources. The company provides accessible scientific information, healthy recipes, and exercise routines to support overall wellness.
4. ProHealth NMN Pro™ 500
Based on the provider claims, we selected ProHealth for our list of top NMN products due to its distinction as the only NMN formulation that has undergone clinical testing for effectiveness in boosting NAD+ levels. The brand demonstrates a strong commitment to transparency, providing clear information on its production methods, quality certifications, formulas, and usage instructions.
ProHealth has updated its website and bottle designs while maintaining high product quality by sourcing NMN from a reputable supplier Uthever®. In a clinical study Uthever® NMN has been reported to increase NAD+ levels by 38% from baseline.
ProHealth NMN Pro™ 500 displays third-party lab test results that confirm the NMN's quality, though the purity percentage is not specified.
The recommended dosage is 2 capsules daily, delivering a total of 500 mg of NMN. ProHealth NMN Pro™ 500 is free from major allergens, gluten, soy, and animal products and is manufactured in facilities that comply with FDA and cGMP standards.
A 30-serving bottle of ProHealth NMN Pro™ 500 is priced at $58.
Main Ingredients
- Uthever™ β-nicotinamide mononucleotide
Key features of ProHealth NMN Pro™ 500
- Purity: Does not display.
- Amount of NMN: 500 mg.
- Additional ingredients: None.
- Our pick for: Best NMN to increase NAD levels.
Company review
ProHealth Longevity, established by Rich Carson in 1988, is a Canadian company known for delivering high-quality supplements designed to address health concerns similar to those Carson initially faced. Over the years, ProHealth has earned a strong reputation for excellence and has maintained an A+ rating with the Better Business Bureau for 35 years.
Building on its success, ProHealth Longevity has expanded its focus to include research on longevity. The company is committed to advancing science-backed supplements aimed at enhancing both lifespan and healthspan. In addition to a diverse range of supplements, ProHealth keeps its customers updated with the latest research on aging and longevity.
5. Omre NMN + Resveratrol
Omre offers an NMN product combined with 98% resveratrol, aiming to improve healthspan by potentially increasing NAD+ levels but also through the activation of sirtuin genes. By combining these two ingredients into a single capsule, the manufacturer makes the product a more convenient option for people seeking accessible methods to longevity.
To potentially improve the bioavailability of resveratrol, the provider added BioPerine® — black pepper extract. To further enhance the absorption of resveratrol and NMN, the manufacturer of Omre recommends taking 2 capsules in the morning with healthy fat.
Each capsule of Omre NMN + Resveratrol contains 250 mg of NMN and resveratrol and 5 mg of black pepper extract. Capsules are free from fillers and binders, they are suitable for vegans.
Omre NMN + Resveratrol is produced in GMP-certified and FDA-registered facilities. The product undergoes third-party testing to ensure quality.
A bottle of Omre NMN + Resveratrol for a 30-day supply is priced at $59.97.
Main ingredients
- β-Nicotinamide mononucleotide
- Trans-resveratrol
- BioPerine®
Key features of Omre NMN + Resveratrol
- NMN purity: 98%.
- Amount of NMN: 500 mg.
- Additional ingredients: Resveratrol and BioPerine®.
- Our pick for: Best NMN-resveratrol product.
Company review
Omre, a UK-based company founded by Dr. Pedram Kordrostami, is dedicated to developing science-backed supplements tailored to diverse health needs. Their primary mission is to achieve outstanding results by using high-quality, bioavailable ingredients and effective dosages.
The company prioritizes research over unproven trends, focusing on creating products that might enhance healthspan. This commitment is reflected in their name, "Omre," which means "lifespan" in Farsi.
6. Purovitalis Liposomal NMN
A prominent longevity company based in the Netherlands, Purovitalis is dedicated to addressing aging-related health challenges through innovative supplement formulations. Their online store offers a wide range of products, including 99% NMN made in the EU under cGMP-certified conditions.
The company uses liposomes made from sunflower lecithin, aiming to enhance NMN bioavailability. Each capsule of Purovitalis Liposomal NMN contains 250 mg of NMN, with a recommended daily dosage of 2 capsules in the morning and evening.
The company offers 3 supply options for 2 to 8-month consumption. A bottle containing 120 capsules with 2 months supply is available at $105.
The price is made more reasonable with free shipping within the U.S. Purovitalis is also available for worldwide orders with affordable delivery rates.
Main ingredients
- Longevir™ β-Nicotinamide mononucleotide
Key features of Purovitalis Liposomal NMN
- Purity: 99%.
- Amount of NMN: 250 mg.
- Additional ingredients: None.
- Our pick for: Best pure NMN product.
Company review
Purovitalis aims to be more than just a supplement provider; it strives to be a partner in your longevity journey. Their team of scientists develops products based on scientific research to support all stages of life. Emphasizing a holistic approach, Purovitalis encourages its customers to combine quality supplements with a healthy lifestyle to help maximize results.
7. Wonderfeel Youngr NMN
Wonderfeel Youngr NMN, produced in the U.S., adheres to advanced manufacturing standards. The brand is notable for its environmental commitment, providing refill bottles for initial orders and eco-friendly, plastic-free packaging for subsequent refills.
This NMN product is highly rated in 2025 for its all-in-one formula. It undergoes third-party testing and includes antioxidants to potentially enhance the benefits of NMN.
Wonderfeel Youngr NMN is non-GMO, preservative-free, and free from major allergens. In addition to NMN, each capsule contains 2 mg of ergothioneine, 50 mg of trans-resveratrol, 40 mg of olive leaf plant extract, and 10 mcg of vitamin D3.
The advised daily dosage is 2 capsules, providing a total of 900 mg of NMN. Clinical trials indicate that NMN doses up to 1,250 mg/daily might be safe for up to 1 month.
According to the manufacturer, to optimize the absorption of certain ingredients, it is recommended to take the capsules with healthy, fat-rich foods.
Wonderfeel Youngr NMN can be purchased on the brand's official website. Orders over $60 receive free shipping within the U.S. A single bottle costs $88.
Main ingredients
- β-Nicotinamide mononucleotide
- Trans-resveratrol
- Vitamin D
- Olive fruit leaf extract (with 25% of Hydroxytyrosol)
- Ergothioneine (ERGO)
Key features of Wonderfeel Youngr NMN
- Purity: 98%.
- Amount of NMN: 900 mg.
- Additional ingredients: Olive fruit leaf extract, resveratrol, ergothioneine, vitamin D3.
- Our pick for: Top-rated eco-friendly NMN product for anti-aging.
Company review
Wonderfeel, headquartered in San Francisco, specializes in longevity solutions, utilizing advanced bioscience to create research-based products designed to help enhance healthspan and extend lifespan.
Under the leadership of Dr. Andrew Salzman, a distinguished physician and inventor with a deep background in drug discovery and development, Wonderfeel focuses not just on product effectiveness but also on sustainability.
Expert opinion
NMN supplements are getting more and more popular by the day, but their use still sits in somewhat of a scientific grey area, which has been a subject of lively debate among experts in the field.
And so, to get the latest scoop on NMN supplements, we asked one of our in-house researchers, Dominyka Sitavičiūtė, to share what’s new and what we should know.
Where does NMN stand today?
Early scientific research suggests that NMN supplementation can effectively increase NAD+ levels in the body, which has led to the hypothesis that NMN may play a role in promoting longevity — the main draw of this relatively new compound. Since NAD+ is integral for cellular processes like energy production, DNA repair, and metabolic regulation — all of which are known to be impaired in aging cells — the idea of NMN supplementation does spark interest.
However, despite this promising theoretical foundation, human research backing these claims is still pretty limited. Most studies have small sample sizes, short durations, and some variability in study design.
Although some studies show positive results for metabolic and cardiovascular health, others don’t find significant benefits or even raise questions about long-term safety. From where we stand today, this lack of substantiation keeps the conversation about NMN’s practical applications and potential risks still very much in the air. Personally, I think it’s tough to definitively say whether NMN supplementation is truly beneficial or safe — at least for now and with the current body of research.
NMN consumption
Sitavičiūtė also emphasizes that it’s tough to give clear guidance on how to consume NMN supplements, mainly because there aren’t standardized dosage recommendations or comprehensive safety data available yet.
Because of this, I’d recommend sticking to the manufacturer’s instructions and staying on the cautious side of things for now — choose reputable brands, look for third-party testing and certificates of analysis, and always remember that no supplement can replace a healthy lifestyle and balanced diet. It’s important to keep realistic expectations in mind — while NMN supplements may actually offer potential health benefits, they are not a guaranteed shortcut to significantly extended longevity. After all, they are just supplements.
Dominyka Sitavičiūtė
Is it safe to take NMN products?
The safety of NMN may depend on factors such as dosage, individual health status, and, of course, product quality. Studies that lasted up to 3 months have shown that a regular intake of 250 mg of NMN is typically safe for human consumption.
Nowadays, different products are available in the longevity supplement market, featuring doses ranging from 125 mg to 900 mg of NMN. However, more longitudinal human studies are required to establish safe doses and the effects of long-term usage.
Nonetheless, before starting with any NMN product, you should consult with your healthcare provider for more personalized daily dosage recommendations.
NMN price
The cost of NMN products varies widely, typically ranging from $40 to $120. Prices depend on factors such as the formula, added ingredients, sourcing, testing, and delivery method.
Liposomal NMN or those utilizing delayed-release capsules are often priced higher. These technologies are aimed at advancing the product's bioavailability, however, more research on their effectiveness is necessary.
Where to buy NMN products?
Currently, NMN is not available for purchase as a dietary supplement in the U.S. However, several companies based in the E.U. or the U.S. produce NMN products and deliver them to U.S. customers.
For international buyers, there are reliable NMN options with affordable shipping to Australia, Canada, and the UK.
Check with the provider to ensure the accessibility of NMN products in your region. Consider the laws and regulations governing international shipments of NMN in your country to avoid incurring extra customs taxes.
The best way to increase NAD levels — NMN or NR?
NR (nicotinamide riboside), a form of vitamin B3, is another well-known precursor to NAD+. Yet some scientists and brands claim that NR may be inferior to NMN in terms of its conversion efficiency into NAD+.
It is suggested that while NR takes two steps to convert into NAD in the body, NMN requires only one, making it a more rapid precursor. Despite these claims, further studies are necessary to determine the superior NAD+ precursor conclusively.
Benefits of NMN supplements
The most frequently reported benefits following NMN consumption among users are improved sleep, increased energy, and enhanced cognitive function, however some of them do have not been evaluated and reported in scientific literature.
However, multiple limited human studies have shown NMN products to augment NAD+ levels, which may lead to several potential health benefits.
1. Physical function support
Clinical studies evaluating the effects of NMN on physical function reported that NMN improved the aerobic capacity of young and middle-aged recreationally trained runners when used during exercise training.
Another study demonstrated that NMN intake over 12-week period taken daily in the afternoon significantly enhanced lower limb function in older adults.
In another study with middle age healthy adults, doses up to 900 mg/day over 60 day of NMN significantly improved physical endurance, as demonstrated by notable enhancements in the six-minute walking test
The same outcomes have been reported in a study with 60 older adults where NMN contributed to improved sleep quality and helped maintain walking speed after 12 weeks compared to the placebo group.
2. May help with insulin sensitivity
A study in postmenopausal women with prediabetes and overweight or obesity reported that NMN may improve muscle insulin sensitivity and insulin signaling and remodeling, however, other studies looking at similar outcomes did not observe significant changes.
3. May help with blood lipid profile
A formulation of NMN (MIB-626) has been reported to significantly reduce total LDL and non-HDL cholesterol, while another study of acute intravenous NMN injection reported that it resulted in reduced triglyceride levels.
4. May help manage age-related weight gain
It is hypothesized that as NAD+ levels drop with age, metabolism may slow down, potentially leading to weight gain. Limited studies on rodents suggest a link between age-related weight gain and declining NAD+ levels. Potential improvements in insulin sensitivity and help with blood lipid regulation may also assist in maintaining weight in a healthy range.
NMN products may help restore NAD+ levels, aiding in weight regulation. However, more robust evidence from human studies is needed.
Other potential benefits of NMN products
Increased NAD+ levels may offer additional health benefits, according to limited studies in cell cultures, animals, and humans. Potential benefits include:
- DNA repair
- Energy production
- Cellular health
- Heart health
- Liver health
- Metabolic health
- Immune function support
- Reproductive health
Comparison of NMN delivery methods
NMN can be taken in various forms: capsules, sublingual tablets, nasal or oral sprays, and powders. Each method has a unique absorption pathway before NMN is converted to NAD+. Here’s a breakdown:
Powder NMN
Popular among biohackers, powder NMN is often preferred for its purity, without fillers or coatings. It may also be a cost-effective option due to simpler manufacturing and packaging. However, dosing can be unreliable, and it may require mixing into smoothies, shakes, or custom capsule creation.
Liposomal NMN capsules
Liposomal NMN encapsulates molecules in liposomes, protecting them from the digestive tract’s acidity, and is believed to improve the compound’s bioavailability. This means the NMN may reach the target areas intact, possibly requiring lower doses. While further studies are needed, liposomal technology is believed to enhance NMN absorption.
Sublingual NMN products
Sublingual tablets dissolve under the tongue, potentially allowing NMN to be absorbed directly into the bloodstream. However, scientific consensus on the bioavailability of sublingual NMN is still lacking.
Intranasal NMN
Intranasal delivery involves spraying NMN into the nasal cavity, potentially allowing it to be absorbed by the nasal epithelium and enter the bloodstream. Yet, some users find the taste of intranasal NMN acidic and report it as unpleasant.
FAQ
Can you take NMN with resveratrol?
Currently, there is no clinical research looking at the safety and potential effects of using NMN and resveratrol in combination. Many NMN products include both NMN and resveratrol in a single capsule, offering more convenience, however, it is important to consult a healthcare provider before combining multiple products with active ingredients.
What is the best NMN supplement?
While we have partiQlar as our top pick, choosing the right NMN supplement involves factoring in several factors, including making sure the dosage suits your health needs. Beyond price, look for brands that offer products tested by a third-party, clinically backed doses, and solid manufacturing practices.
Is NMN safe for kidneys?
Currently, no clinical studies have identified any potential risks of using NMN on kidney health. Research on animals and limited human studies suggest NMN may benefit various kidney health parameters. However, it is important to consult your healthcare provider before incorporating NMN into your routine, to ensure it is safe and suitable for your health needs.
Are all NMN products FDA-approved?
No. NMN products are not FDA-approved and are under investigation as potential drug ingredients.
Where can I buy NMN products?
NMN supplements are available online, primarily through the manufacturers' websites, and are not sold in physical stores.
Can NMN reverse gray hair?
No. While NMN can improve certain metabolic and cellular processes, it does not reverse gray hair.
Can NMN help with bodybuilding?
There is no clinical evidence that NMN aids bodybuilding. Some limited studies suggest NMN might enhance physical performance and muscle endurance, but more research is needed to confirm its effectiveness for bodybuilders.
7 resources
- Frontiers. Nicotinamide Mononucleotide: A Promising Molecule for Therapy of Diverse Diseases by Targeting NAD+ Metabolism.
- Cureus. Nicotinamide Mononucleotide Is Safely Metabolized and Significantly Reduces Blood Triglyceride Levels in Healthy Individuals.
- JCEM. Nicotinamide Adenine Dinucleotide Augmentation in Overweight or Obese Middle-Aged and Older Adults: A Physiologic Study.
- Science. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women.
- GeroScience. Ingestion of β-nicotinamide mononucleotide increased blood NAD levels, maintained walking speed, and improved sleep quality in older adults in a double-blind randomized, placebo-controlled study.
- GeroScience. The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial.
- Nutrients. Effect of 12-Week Intake of Nicotinamide Mononucleotide on Sleep Quality, Fatigue, and Physical Performance in Older Japanese Adults: A Randomized, Double-Blind Placebo-Controlled Study.
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