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Best B Complex Vitamins: Top Recommendations

B-complex vitamins are integral to our health, supporting various physiological functions, from energy production to cognitive performance. They include thiamine (B1), riboflavin (B2), niacin (B3), pantothenic acid (B5), pyridoxine (B6), biotin (B7), folate (B9), and cobalamin (B12).

Certain factors such as age, medical conditions, and lifestyle choices can lead to deficiencies in B vitamins. In such cases, supplementation may be necessary to meet the body’s needs and prevent health issues related to vitamin B deficiency.

But with so many available options, you might be wondering which ones are the best. In this article, we provide the top B-complex vitamins from our research, considering factors like brand reputation, third-party testing, and ingredient quality to ensure you make a good choice. We also discuss the science of B-complex vitamins and things you should consider to select the best vitamin B-complex for your needs.

Best B-complex vitamins: shortlist

After extensive research by our team, we have shortlisted the best vitamin B complex supplements:

  1. Performance Lab — best food-like B vitamin complex
  2. Ancient Nutrition — best animal derived B vitamin complex
  3. New Chapter — overall best B-complex supplement
  4. Botanic Choice — best vitamin B-complex supplement for seniors
  5. Nature Made — best vitamin B-complex supplement for women
  6. Nutricost — best vitamin B-complex supplement for nerve damage
  7. NatureWise — best soft gel B-complex supplement
  8. NOW — best B-complex supplement for anxiety
  9. MegaFood — best B-complex supplement for energy
  10. Nature's Craft — best value for money vitamin B-complex supplement

How did we compile the list of the best B-complex vitamins?

Here is a breakdown of our selection criteria:

Ingredient qualityBrand reputationCertificationsIngredient transparencyPrice
Gluten-free, non-GMOGood product history and positive customer feedbackNSF, B Corporation, Kosher, and othersComplete ingredient lists$4.99–65.00
  • Ingredient quality. We prioritized products that use high-quality, natural, and non-GMO ingredients.
  • Brand reputation. Brands with a history of quality products and positive customer feedback were preferred.
  • Certifications. We looked for products that had relevant certifications from recognized bodies.
  • Ingredient transparency. Only brands that list all the ingredients and the quantities on their product labels made it to our list.
  • Price. We selected products that offer good value for money.

Top picks: best B-complex vitamins

In this section, we will explore our top picks for the best B-complex supplements, discussing their features, doses, usage instructions, third-party testing, pros and cons, and other important details like warnings from manufacturers.

Let’s dive in!

1. Performance Lab — best food-like B vitamin complex

Performance Lab® B-Complex

Performance Lab’s B-Complex employs a unique NutriGenesis technology, that according to the brand is based on Nobel Prize winning research, to deliver B vitamins in similar forms that are found naturally in food. These vitamins are produced by supplying their sources with other important factors, such as probiotics, fibre, enzymes, and antioxidants, creating more well-rounded supplements that are close to their natural counterparts. They are also free of pesticides and toxins that may be present in conventionally farmed plants.

The complex includes all 8 B vitamins that may boost energy, improve mood, enhance focus, mental clarity, and support overall health. With overtime use, the complex may also improve the quality of skin, hair, and nails.

The supplement is non-GMO, soy-, gluten-, caffeine-, synthetic additive-, and allergen-free. The capsules are also vegan, making them suitable for most diets.

Performance Labs products are third-party tested to ensure adherence to the ingredients, all of which are transparently shown on the label

The serving size is just one capsule a day, that can be taken with or without food.

30 servings costs $44.00 for one-time purchase ($1.46 per serving), the price gets lower if you buy several month’s supply or subscribe.

2. Ancient Nutrition — best animal derived B vitamin complex

Ancient Nutrition Vitamin B Complex

Ancient Nutrients Vitamin B complex, stands out from its competitors by being derived from real food sources, inspired by the Traditional Chinese Method. The product includes Grass-fed New Zealand cattle liver and wild hake roe, both of which are excellent sources of B vitamins, as well as high in iron, zinc, magnesium, and selenium. Some animal origin vitamins are more easily absorbed by our system, due to similarities to the ones found in food.

Additional ingredients include reishi mushroom, which has been used in traditional Chinese medicine for centuries, and may support immune system function. Other superfoods and adaptogens, such as astragalus roots, green tea leaf, schisandra berry, and fo-ti root may provide additional antioxidant and health-related benefits. The inclusion of bone broth may also support collagen production.

The overall well rounded formula may boost energy, promote cardiovascular and eye health, provide cognitive and neurological support, and improve sleep. Skin, nail, and hair quality may also improve.

The serving size is 2 capsules daily. The product is third-party tested for label accuracy.

However, pyridoxine (B6) dose is high in this product and prolonged intake of high doses of pyridoxine may be associated with peripheral neuropathy, thus you should consult a healthcare professional before using this product.

30 servings costs $80.87 ($2.7 per serving).

3. New Chapter — best brand vitamin B-complex

New Chapter Fermented Coenzyme B Complex

New Chapter Fermented Coenzyme B-Complex supplement is a B-vitamin complex that stands out for its fermentation process. The brand claims this process enhances the vitamins' bioavailability, making them easier for the body to absorb and use.

It contains B-complex vitamins that play essential roles in energy production, immune function, and brain health.

In addition to the B vitamins, the supplement also contains organic ingredients such as schizandra, maca, chamomile, oregano, hawthorn, grapeseed extract, European elder, eleuthero, astragalus, turmeric, and ginger. These ingredients contribute to the supplement’s use in supporting health.

The supplement is third-party verified, ensuring high standards of quality and purity. The provider recommends taking one tablet daily.

A container with 30 servings costs $30.

Note: There are concerns regarding heavy metal contamination in maca root.

4. Botanic Choice — best vitamin B-complex for seniors

Botanic Choice Super B-100 Complex™

Botanic Choice Super B-100 Complex contains ingredients including choline 50 mg, inositol 100 mg, PABA 100 mg, calcium 39 mg, phosphorus 30 mg, and the eight B vitamins.

This supplement is gluten and GMO-free and has 50 tablets per container. The company ensures that its products are tested, manufactured, and re-tested under strict cGMP/FDA guidelines in the U.S.

The provider recommends taking one tablet twice daily.

Each bottle costs $15 and comes with a 90-day return policy.

5. Nature Made — best vitamin B-complex for women

Nature Made B-Complex with C Caplets

Nature Made B-Complex with C Caplets is designed to deliver five essential B vitamins and vitamin C 300 mg for immune system support. The B vitamins in this product include B1, B2, B3, B5, and B6.

The supplement has no color-added or artificial flavors and is gluten-free. Each batch is USP-tested and verified, ensuring high-quality standards.

The manufacturer suggests taking one caplet daily with water and a meal.

The price of a container with 100 servings is $11.39.

6. Nutricost — best vitamin B-complex for nerve damage

Nutricost Vitamin B Complex Capsules

Nutricost Vitamin B Complex supplement provides 460 mg of B-complex per serving. Other key ingredients in the formulation (120 capsules bottle) include vitamin C 40 mg, inositol 50 mg, and choline bitartrate 50 mg. It is also available in the 240-serving bottle, which contains 20 mg of choline in addition to the ingredients in the 120-capsule bottle.

The supplement is made in an FDA-inspected facility and is third-party tested by ISO-accredited labs.

Nutricost Vitamin B Complex capsules are non-GMO and gluten-free. The provider recommends taking one capsule daily.

Each bottle containing 120 capsules costs $17.95 for a one-time purchase.

7. NatureWise — best liquid B-complex (in soft gel form)

NatureWise Vitamin B Complex

NatureWise, the Vitamin B Complex delivers the eight vitamins in a soft gel form. Other ingredients in the product are gelatin, flaxseed oil, extra virgin olive oil, glycerin, purified water, yellow beeswax, sunflower lecithin, and annatto. Flaxseed oil and extra virgin olive oil help your body absorb and use the vitamins to ensure you get the most health benefits.

It is free from artificial colors and flavors, making it a safe and natural choice for those looking to supplement their vitamin B intake. Also, it is free from common allergens like wheat, dairy, peanut, soy, gluten, fish, and tree nuts.

Each batch is third-party tested for quality and purity. Nature Wise recommends taking one soft gel daily.

One bottle containing 60 servings costs $4.99, with a 60-day money-back guarantee.

8. NOW — best B-complex vitamins for anxiety

NOW Supplements Vitamin B-100

The NOW Vitamin B Complex supplement is available in two sizes, which offers flexibility. It also contains choline 10 mg, inositol 10 mg, and PABA 10 mg, in addition to the eight B vitamins.

This supplement is produced in a GMP-compliant facility. It is not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, or tree nut ingredients, making it allergen-friendly. However, it is important to note that the supplement is produced in a facility that processes other ingredients containing these allergens. This is something to consider if you have severe allergies or sensitivities.

The recommended dosage is one capsule daily with a meal.

One bottle with 100 servings is priced at $22.39 and has a 30-day return policy.

9. MegaFood — best B-complex supplement for energy

MegaFood Balanced B Complex

The MegaFood Balanced B Complex is formulated to deliver good levels of the eight B-complex vitamins and a 258 mg organic food blend of brown rice, kale, and broccoli.

This supplement is vegan, kosher, and non-GMO, making it suitable for various dietary preferences.

This product has third-party certifications, including Certified B Corporation, Certified Glyphosate Residue Free, Non-GMO Project Verified, Certified Vegan, and Certified Kosher. It is also made without milk, eggs, peanuts, tree nuts, soy, wheat, fish, shellfish, and sesame.

The brand recommends taking one tablet daily with a beverage.

A 30-day supply of the MegaFood Balanced B Complex supplement costs $15.49.

10. Nature's Craft — best B-complex supplement for value

Nature's Craft Super B Complex

Nature’s Craft Super B Complex contains eight B-complex vitamins with 40 mg of choline, inositol 100 mg, and PABA (Para-Aminobenzoic Acid) 100 mg. Inositol may affect mood positively, choline is needed for brain function, and PABA has antioxidant properties.

The supplement is made in an FDA-inspected facility and is third-party lab-tested. The company recommends taking one tablet daily, preferably with meals. Nature’s Craft states that consuming this product may expose you to harmful heavy chemicals like lead and arsenic.

One bottle contains 100 servings, priced at $15.77 for a one-time purchase.

Comparison of the best B-complex vitamins

Here is a close comparison of the top B-complex supplements on the market:

BrandPriceServings per containerServing sizeVitamin B1 doseVitamin B2 doseVitamin B3 dose Vitamin B5 dose Vitamin B6 doseVitamin B7Vitamin B9 doseVitamin B12 dose
Performance Lab$44301 capsule1.2 mg1.4 mg16 mg6 mg1.6 mg150 mcg680 mcg10 mcg
Ancient Nutrition$80.87302 capsules5.2 mg13.1 mg12 mg15 mg63 mg300 mcg900 mcg20 mcg
New Chapter$30.00*30, 60, 901 tablet5 mg3.9 mg45 mg45 mg9 mg300 mcg392 mcg120 mcg
Botanic Choice$15.00501 tablet100 mg100 mg100 mg100 mg100 mg100 mcg400 mcg100 mcg
Nature Made$11.391001 caplet15 mg10.2 mg50 mg10 mg5 mgN/AN/AN/A
Nutricost$17.95*120, 2401 capsule60 mg75 mg35 mg100 mg50 mg600 mcg400 mcg1000 mcg
NatureWise$4.99*60, 150, 3601 soft gel2.25 mg2.55 mg30 mg10 mg3 mg300 mcg400 mcg6 mcg
NOW$22.39*100, 2501 capsule100 mg100 mg100 mg100 mg100 mg100 mcg400 mcg100 mcg
MegaFood$15.49*30, 60, 901 tablet9 mg4 mg45 mg45 mg10 mg30 mcg400 mcg50 mcg
Nature's Craft$15.771001 tablet100 mg100 mg100 mg100 mg100 mg100 mcg400 mcg100mcg

Best vitamin B-complex for seniors

Studies have shown older adults to be deficient in B vitamins such as B6, B9, and B12 due to factors including reduced food intake and absorption efficiency.

Research shows that B vitamins, particularly B6, B9, and B12, support brain health and may help reduce the risk of cognitive decline and dementia. A 2021 systematic review and meta-analysis of 21 randomized controlled trials (RCTs) found that vitamin B supplements might delay or maintain the cognitive decline of elderly adults.

Also, B vitamins are involved in many processes in the body, such as energy production. These processes can become less efficient as we age, so having enough B vitamins to support them is essential.

The best vitamin B complex for seniors should have the specific B vitamins seniors most likely need. These include vitamins B12, B6, B9, and B3, and other B vitamins like B1, B2, B5, and B7.

Best B-complex vitamins for anxiety

Research suggests that B vitamins may have a positive influence on anxiety. A 2021 study that included Iranian adults suggests that a higher intake of dietary B vitamins, especially biotin, may be associated with a lower prevalence of depression, anxiety, and stress symptoms.

Vitamins B6 and B12 help to maintain a balance between neural excitation and inhibition. An equilibrium towards excitation has been implicated in neuropsychiatric disorders, including depression and anxiety.

The best B-complex supplements for anxiety should preferably contain the eight B vitamins (B1, B2, B3, B5, B6, B7, B9, B12).

However, it is best to consult a healthcare provider for personalized advice before starting any new supplement regimen.

How to choose the best B-complex vitamins?

Selecting the best B-complex vitamin supplement can be challenging, given the number of options available on the market. Here are key factors to consider:

  • Additional ingredients. Some B-complex vitamins may contain additional ingredients such as herbs or other vitamins. While these can be beneficial, it is crucial to ensure they are safe. It may help to check the label for additional ingredients and research their benefits and potential side effects.
  • Third-party testing. Supplements that a third-party organization has tested offer an extra level of assurance about their quality and purity. These organizations verify that the product contains the ingredients listed on the label and doesn’t contain harmful levels of contaminants.
  • Reputable providers. Companies with a long history in the industry or those recommended by healthcare professionals are often more reliable.
  • Price. The cost of B-complex vitamins can vary widely based on factors like brand, quantity, and where you purchase them from. Comparing prices from different providers can be a helpful strategy.

The science behind vitamin B-complex

B vitamins are involved in various physiological processes vital for health, encompassing energy production to immune regulation.

They have two main roles: helping our bodies convert food into energy, a process known as catabolic metabolism, and assisting in creating essential molecules in our bodies, known as anabolic metabolism.

Also, B vitamins are crucial for the proper functioning of our nervous system. They help transport signals along our nerve cells and are involved in producing neurotransmitters, the chemicals that allow our brain cells to communicate.

In addition, B vitamins are essential for the synthesis of RNA and DNA, the building blocks of our cells.

Deficiencies in B vitamins can lead to various health issues like confusion and fatigue. Therefore, maintaining adequate levels of these vitamins is vital for our overall health.

Concluding recommendations for best B-complex vitamins

B-complex vitamin supplementation is primarily recommended to correct deficiencies, as they are essential for various bodily functions. However, if you have adequate dietary intake of B vitamins from sources like legumes, leafy greens, and animal products, additional supplementation may not offer significant extra benefits.

It is important to consult with a healthcare professional to assess individual needs, especially for certain populations like vegetarians, vegans, older adults, and those with specific medical conditions.


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