Knee and joint discomfort can significantly affect daily life, making movement difficult and reducing overall well-being. To find relief, many people are trying CBD products for their potential to reduce inflammation and relieve pain, amongst other uses. CBD (cannabidiol) is a natural compound from hemp that has gained significant attention for its reported therapeutic benefits.
Numerous products promise relief from knee and joint pain with the growing CBD market. But choosing the right one can be confusing. To help you, we've carefully selected the top five CBD products formulated to support knee and joint issues, making your decision easier.
Best CBD for knee pain: shortlist
- Aspen Green Relief Balm — best full-spectrum CBD balm for pain relief
- NuLeaf CBD Balm — best natural CBD balm for reduced local pain and inflammation
- BATCH CBD Balm Fire & Ice — best CBD balm with a soothing effect
- R&R CBD Pain Cream — highest strength CBD cream for localized pain relief
- FOCL Relief Cream — best broad-spectrum CBD cream for pain relief
How we ranked the best CBD for knee pain on the market
Our approach considers critical factors, such as third-party testing, brand reputation, certifications, and price, to evaluate the top CBD products available.
Third-party testing | Independent third-party laboratories |
Certifications | USDA-organic, cGMP certified |
Price | $24–$130 |
Reputation | Brand values, customer reviews |
Ingredients | Organic and non-GMO |
- Third-party testing. We chose products that undergo third-party testing by independent laboratories. This ensures that the CBD products are free from contaminants, harmful substances and accurately labeled with the stated CBD content.
- Certifications. We evaluated relevant certifications, such as GMP (Good Manufacturing Practices) and USDA (United States Department of Agriculture) organic certification, indicating the product's quality, safety, and compliance with industry standards.
- Ingredients. We researched and chose non-GMO products made with natural and organic ingredients.
- Price. We looked for products with good CBD quality at reasonable prices.
- Reputation. We considered brand reputation and positive customer feedback.
Best CBD for knee pain: an overview
The CBD products for knee and joint pain we chose are topicals, meaning they can be applied directly to the skin. They include CBD balms and creams that may relieve knee and joint pain.
After thorough research, we curated the best CBD products for knee and joint pain that you can find in the market today.
1. Aspen Green Relief Balm — best CBD balm for pain relief

AspenGreen’s Relief Balm is a full-spectrum balm formulated to provide relief from pain and discomfort. The balm contains 1000 mg CBD and 33 mg THC (tetrahydrocannabinol). Other key ingredients in the formulation include organic mango butter, organic jojoba seed oil, organic hemp seed oil, and organic beeswax. AspenGreen sources its hemp from organic, non-GMO farms in Colorado, USA.
The brand is USDA certified, and all its products undergo third-party testing with a certificate of analysis for each product available online. The provider recommends applying the balm to the skin as needed. Each 2 Oz / 60 ml jar is priced at $89.99.
2. NuLeaf CBD Balm — best natural CBD balm

NuLeaf CBD Balm is a product designed to support pain management. The product is available in three different sizes, and the amount of CBD is 300 mg, 600 mg, and 900 mg, depending on the container size. The other ingredient in this formulation is organic shea butter.
NuLeaf Naturals holds certifications, including cGMP (current Good Manufacturing Practices), ISO (International Organization for Standardization), Detox Project, and B Corporation. Their products are also third-party tested.
The balm has a firm texture due to the use of shea butter as the carrier. To ease application, the provider suggests gently rubbing the balm between your fingers before applying it as needed. Each jar is priced differently, ranging from $24–$59, based on the container size.
3. BATCH CBD Balm Fire & Ice — best CBD balm with a soothing sensation

BATCH CBD Balm Fire and Ice is a CBD balm formulated to provide pain relief. Just as the name implies (fire and ice), the balm offers a tingling skin sensation attributed to the presence of camphor and menthol.
The amount of full-spectrum CBD in the balm is 1,250 mg. Other ingredients in the balm include organic jojoba oil, organic beeswax, menthol crystals, camphor oil, lemongrass oil, black pepper oil, ginger oil, and vitamin E.
The brand is GMP certified, and all its products are third-party tested, with a certificate of analysis available for each product online. The product comes in the form of a balm stick. The provider recommends twisting up the balm stick until half an inch of the balm is visible and then applying it to the affected area. Each 75 ml balm stick costs $49.99.
4. R&R CBD Pain Cream — highest strength CBD cream for localized pain

R&R CBD Pain Cream is a CBD cream tailored towards reducing local inflammation and promoting relaxation. It is available in three CBD strengths which include 1,000 mg, 2,000 mg, and 5,000 mg.
Other key ingredients in the formulation, in addition to full-spectrum CBD, are Arnica montana, Methylsulfonylmethane (MSM), calendula flower, and jojoba. Arnica montana is a medicinal herb known for its anti-inflammatory potential. Studies suggest that MSM provides pain relief and reduces inflammation.
The brand's products undergo third-party testing, and they adhere to FDA facility standards. The provider recommends applying a quarter-sized amount of cream to the affected area. The price of each 2.5 Oz / 73.93 ml tube ranges from $55–$130, depending on the CBD strength.
5. FOCL Relief Cream — best broad-spectrum CBD cream for pain relief

FOCL Relief Cream is a product formulated to relieve muscle and joint pain. Key ingredients in the product include broad-spectrum CBD extract (1,000 mg or 2,000 mg), menthol, camphor bark oil, eucalyptus leaf oil, aloe vera, arnica extract, and wintergreen oil.
The cream has a cooling effect due to the presence of menthol, eucalyptus, and wintergreen oil. FOCL recommends applying the cream to the affected area three to four times daily. All FOCL products are made in a GMP-compliant facility and are third-party tested. The brand is also TRU-ID certified.
Based on the CBD strength chosen, a one-time FOCL Relief Cream purchase costs $39 or $59.
Comparing the best CBD for knee pain and joint pain
Product | Price (one-time purchase) | Supply size (per container) | CBD type | CBD strength per container | Certificate of analysis | Our pick for |
Aspen Green Relief Balm | $89.99 | 60 ml | Full-spectrum | 1,000 mg | Available online | Best full-spectrum CBD balm for pain relief |
NuLeaf CBD Balm | $24.00, $39.00, $59.00 | 14.2 g, 28.3 g, 42.5 g | Full-spectrum | 300 mg, 600 mg, 900 mg | Available online | Best natural CBD balm for reduced local pain and inflammation |
BATCH CBD Balm Fire & Ice | $49.99 | 75 ml | Full-spectrum | 1,250 mg | Available online | Best CBD balm with a soothing effect |
R&R CBD Pain Cream | $55.00, $85.00, $130.00 | 73.93 ml | Full-spectrum | 1,000 mg, 2,000 mg, 5,000 mg | Available online | Best CBD cream for localized pain |
FOCL Relief Cream | $39.00 | 95.8 g | Broad-spectrum | 1,000 mg | Available online | Best broad-spectrum CBD cream for pain relief |
Choosing the best CBD for knee and joint pain: what to look for?
When searching for the most suitable CBD product to alleviate knee and joint pain, selecting the best products for you might be challenging due to the availability of multiple options, including the CBD form and type. To make an informed choice, here are the key aspects to consider:
Form (oil, gummies, topicals)
Explore the different forms of CBD products available to choose the ones that suit your needs and preferences. Edibles like CBD gummies, usually taste great but may take up to two hours to take effect because they need to be digested.
For faster results, sublingual products such as CBD oils are absorbed under the tongue and dissolved directly into the bloodstream through the mucous membranes, with effects seen in approximately 15 minutes. Topicals, like CBD-infused lotions, balms, and creams, provide localized relief when applied directly to the skin, and therefore may be more suitable for knee pain as compared to CBD products in other forms.
CBD type
Understand the types of CBD products available — full-spectrum, broad-spectrum, and CBD isolate. Full-spectrum CBD contains various beneficial compounds from the hemp plant, including trace amounts of THC (within legal limits). Broad-spectrum CBD retains most cannabinoids but is THC-free, while CBD isolate contains pure CBD without other compounds. Research studies have suggested that THC and CBD may work better when taken together than when taken alone, known as the “entourage effect”.
Brand reputation
Research the brand's reputation in the market and check customer reviews to ensure their products are reliable and offer benefits. Transparency is an essential aspect of a reputable brand. Look for companies that openly share information about their manufacturing processes, sourcing of ingredients, and third-party testing results. A brand that is transparent about its practices is more likely to be trustworthy. It is advisable to approach customer feedback with an open mind because determining authenticity may be difficult.
Third-party testing
It is essential to look for brands that undergo third-party testing to verify the purity and safety of their CBD products. Third-party tested brands usually have a certificate of analysis available online that shows that the product is free of contaminants and contains the amount of CBD or THC stated on the product label.
Can CBD really help with joint pain relief?
Yes. Preclinical and clinical studies suggest a potential pain-relieving effect of CBD in pain-related conditions like arthritis that cause knee and joint pain. However, the clinical studies are limited.
CBD can provide pain relief due to its interaction with the body’s endocannabinoid system. The endocannabinoid system modulates many processes involved in pain sensation, mood, and motivation, among others.
Preclinical evidence suggests that CBD has anti-inflammatory and analgesic properties. In a rat model of knee osteoarthritis, topical application of CBD was associated with reduced pain and inflammation.
A clinical study suggested that CBD may help reduce inflammation caused by inflammatory arthritis.
Extensive clinical research is needed to establish CBD's effectiveness and safety for pain management in human subjects.
How to use CBD for joint pain relief
Both oral and topical CBD have potential benefits for joint pain relief, and the choice of delivery method can be a matter of personal preference. Topical CBD, like CBD cream, is applied directly to the skin, allowing it to be absorbed locally. The advantage of topicals is that they can be applied directly to specific painful areas, making them suitable for joint pain relief.
On the other hand, oral CBD, such as CBD gummies, is primarily absorbed through the digestive system and then enters the body's circulation.
Depending on individual preferences and the targeted area of relief, individuals can opt for either topical or oral CBD for pain relief.
CBD dosage for knee pain and joint pain
Users should always adhere to the how-to instructions provided on the product label, as they may differ for each CBD product. If any side effects occur, discontinue use immediately. Before using any CBD product, it is essential to consult with a doctor to minimize the risk of potential drug interactions. Prior medical advice ensures a safer and more informed experience with CBD products.
As a general guideline, start with a low dosage and gradually increase until you find the optimal amount.
Benefits of CBD for knee and joint pain
CBD offers various benefits for knee pain and joint health, including:
- Reduces Inflammation. CBD's potential anti-inflammatory properties can alleviate joint inflammation, promoting better mobility and comfort.
- Pain Relief. CBD may help reduce pain signals and discomfort associated with knee and joint issues.
- Mood Support. CBD may improve mood due to its interaction with the endocannabinoid system.
- Better sleep quality. By relieving pain, CBD can contribute to improved sleep for users. Also, research studies have shown that cannabinoids may have sleep-supporting effects due to their interaction with the endocannabinoid system in the body.
- Reduces arthritis discomfort. CBD may ease the symptoms of pain and inflammation associated with arthritis due to its anti-inflammatory and pain-relieving properties.
- Reduced side-effects. Compared to conventional painkillers, CBD typically presents fewer and milder side effects.
How soon will CBD work to relieve joint pain?
It depends. The effect of CBD in relieving joint pain can vary among individuals. Factors such as the product's strength, dosage form, and an individual's response can influence the time it takes for CBD to work.
Generally, when CBD is taken orally, such as with CBD oil or gummies, it may take around 30 minutes to 2 hours to feel the effects because it needs to pass through the digestive system before entering the bloodstream. On the other hand, when using topical CBD products like creams or balms, the relief may be more localized and quicker to take effect, typically within 15 to 45 minutes.
How else can CBD help besides joint pain relief?
Apart from joint pain relief, other potential benefits of CBD include:
Might protect against neurological diseases
Emerging research suggests that CBD might hold promise in protecting against neurological diseases such as multiple sclerosis. Its lipophilic nature allows it to easily access intracellular sites, where it can influence calcium homeostasis — a critical process in nerve cell function. By modulating cellular processes within nerve cells, CBD shows potential neuroprotective properties.
Can alleviate ALS symptoms
Cannabinoids show promise in delaying Amyotrophic Lateral Sclerosis (ALS) symptoms. Preclinical studies suggest that modulating the CB2 receptor found in glial cells may mitigate inflammation and delay disease progression. Further research is needed, but cannabinoids' neuroprotective and anti-inflammatory properties may offer hope for ALS management.
May relieve anxiety
Research studies have found CBD to have various relaxation and anti-anxiety effects, but more research is needed to confirm its efficacy.
Can CBD for joint pain management cause side effects?
CBD has minimal abuse potential and is generally well tolerated. The most commonly reported side effects of CBD include:
- Drowsiness
- Fatigue
- Dry mouth
- Nausea
- Reduced appetite
- Diarrhea
It is important to note that the incidence of side effects varies from person to person, and not everyone will experience these effects. To minimize the risk of side effects with CBD use, it is advisable to start with a low CBD dosage and gradually increase it as needed while closely monitoring your body's response.
If you are considering using CBD for joint pain management, it is recommended to consult with a healthcare professional, especially if you have any pre-existing medical conditions or are taking other medications, to ensure its safe use.
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FAQ
What is the best CBD for joint pain relief?
Based on our review, AspenGreen Relief Balm is the best CBD for joint pain relief. The balm contains 1000 mg of CBD. Remember to choose a product that suits your preferences, such as topical balms or creams, and consider factors like CBD strength and other ingredients.
Can CBD help with arthritis knee pain?
Yes. CBD has shown potential in helping with arthritis knee pain. Preclinical and some limited clinical studies suggest that CBD's anti-inflammatory and analgesic properties may be beneficial in managing pain and inflammation associated with arthritis. However, the benefits may vary among individuals.
What strength of CBD is best for joint pain?
It depends. The ideal CBD strength for joint pain varies based on factors like body weight, pain severity, and CBD tolerance. Consider starting with a moderate 1000 mg CBD product, then gradually increase the strength until you achieve the desired relief.
Is CBD as effective as ibuprofen?
It is too early to conclude. Although CBD has shown potential as an alternative for managing pain and inflammation, it is important to note that there are no studies directly comparing CBD with ibuprofen.
- Springer. Cannabidiol (CBD) in Rheumatic Diseases (Musculoskeletal Pain).
- PMC. Cannabidiol (CBD): a killer for inflammatory rheumatoid arthritis synovial fibroblasts.
- Wiley Online Library. The CB2 cannabinoid agonist AM-1241 prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis when initiated at symptom onset.
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