Inositol, a natural sugar-alcohol compound, has gained popularity in supplement formulations for its suggested benefits. This includes increased fertility and prevention of gestational diabetes, as well as weight loss support, especially in women with polycystic ovary syndrome (PCOS) and in individuals with overweight and obesity.
Both men and women may potentially benefit from inositol usage. If your healthcare provider has recommended using the compound and you are now searching for the best inositol supplement, we created this guide to simplify the selection.
Below, we provide you with reviews of 10 top-rated inositol products we selected based on their formula, customer reviews, price per serving, and other quality factors.
Best inositol supplement: shortlist
- Bird&Be — best inositol powder for PCOS support
- Momentous — overall best inositol supplement
- O Positiv — overall best inositol supplement for ovarian health
- Life Extension — best price per serving for inositol
- Double Wood — best myo-inositol supplement
- Natalist — best inositol supplement for versatile use
- Femometer — best inositol supplement for PCOS
- Nutricost — best inositol supplement for mood
- BulkSupplements.com — good inositol supplement for health
- GNC — solid inositol supplement brand
Your well-being is our top priority. Our in-house Research team and expert fact-checkers diligently review every content piece, ensuring you receive accurate, safe, and up-to-date health information to support your health decisions. Get an inside look at our thorough testing framework.
Comparison of the best inositol supplements
| Brand | Price | Price per serving | Servings per bottle | Serving size | Active ingredients |
| Bird&Be | $40.00 | $1.33 | 30 | 1 sachet | Myo- and D-chiro-inositol, magnesium citrate |
| Momentous | $24.95 | $0.41 | 60 | 1 capsule | Myo-inositol |
| O Positiv | $42.99 | $1.43 | 30 | 3 capsules | Folic acid, DIM, Myo- and D-chiro-inositol |
| Life Extension | $47.25 | $0.13 | 360 | 1 capsule | Myo-inositol |
| Double Wood | $44.85 | $0.49 | 90 | 2 capsules | Myo-inositol |
| Natalist | $35.00 | $1.16 | 30 | 4 capsules | Myo- and D-chiro-inositol |
| Femometer | $35.99 | $1.19 | 30 | 3 capsules | Myo- and D-chiro-inositol |
| Nutricost | $19.95 | $0.08 | 240 | 1 capsule | Inositol |
| BulkSupplements.com | $21.96 | $0.36 | 60 | 2 capsules | Inositol |
| GNC | $19.99 | $0.19 | 100 | 1 tablet | Inositol |
Best inositol supplement of 2024: product reviews
In the upcoming sections, we will review 10 brands to help you identify the best inositol supplement suitable to your health goals. Our nominations also considered whether the supplements are cost-effective or may provide specific health benefits as their primary aspect.
1. Bird&Be — best inositol powder for PCOS support
If taking capsules is challenging for you, consider trying Bird&Be's PCOS Support inositol supplements in powder form. Designed for women with PCOS, this supplement aims to support those trying to conceive and help manage the symptoms associated with this condition.
Bird&Be PCOS Support is said to be formulated by a fertility specialist in science-backed doses. The amount of MI and DCI are often recommended for ovulation assistance, egg quality while TTC, insulin sensitivity, and hormonal balance.
The daily recommended intake is 1 sachet of powder mixed with water or juice, preferably in the morning. The powder is climbed to be vegan, free from flavor and major allergens.
Key features of Bird&Be inositol
- Inositol amount: 4000 mg MI and 100 mg DCI.
- Additional ingredients: Magnesium citrate.
- Daily dosage: 1 sachet.
- Certificates: cGMP-certified facilities.
A one-month purchase of this supplement is $40 ($1.33 per serving). PCOS Support inositol powder by Bird&Be is FSA/HSA-eligible, so you can ease the financial burden by paying from these funds. Also, with a monthly subscription, you can save 10% on each supply.
2. Momentous — best inositol supplement for sleep and fertility
The provider of the Momentous inositol supplement asserts this formulation may enhance sleep when consumed 30–60 minutes before bedtime. Customer reviews praise this supplement as the best inositol for sleep, citing its effectiveness in helping to sleep through the night.
While a small number of studies show that changes in Myo-inositol levels in the brain may be linked to depressive symptoms and associated sleep difficulties in young individuals, more research is needed to ascertain these benefits.
Momentous vegan capsules contain Myo-inositol derived from plant-based ingredients. The manufacturer recommends using the supplement not more than 3–4 nights a week and giving it 2–4 days to see the results.
Key features of Momentous inositol
Here are the key features that Momentous inositol possesses:
- Inositol amount: 900 mg of MI.
- Additional ingredients: None.
- Daily dosage: 1 capsule.
- Certification: cGMP-certified facilities and NSF-certified for Sports.
One bottle of Momentous inositol contains 60 capsules for a 60-day serving. A one-time purchase of this supplement costs $24.95 ($0.41 per serving).
3. O Positiv Health — overall best inositol supplement for ovarian health
In case you are looking for all the good stuff for hormonal support and ovarian health in one capsule, you may consider O Positiv with its FLO ovarian support capsules. This is a combination of 4 ingredients known for their benefits for female reproductive health.
Besides containing D-chiro and Myo-inositols, FLO ovarian support capsules contain two distinct ingredients — folic acid and Diindolylmethane (DIM). While the former, as vitamin B9, is involved in normal reproductive health in women, the latter is suggested to play a role in estrogen metabolism and hormonal weight management.
O Positiv FLO manufacturers recommend taking 3 capsules once daily with water for at least 3 months. Yet, you should also consult your healthcare provider for the most accurate recommendations suitable for you.
Key features of O Positiv FLO inositol
- Inositol amount: 2000 mg MI and 50 mg DCI.
- Additional ingredients: Folic acid and DIM.
- Daily dosage: 3 capsules.
- Certificates: cGMP-certified facilities.
O Positiv provides flexible purchasing options to suit your needs. For a one-time purchase, you can manually order your monthly supply of FLO and choose the desired number of bottles. Alternatively, you can subscribe for automatic deliveries, where you can customize the frequency and the number of bottles to be delivered.
A bottle of FLO ovarian support capsules for 30 servings costs $42.99 ($1.43 per serving).
4. Life Extension — best price per serving for inositol supplement
For someone looking for a yearly supply of inositol supplements, Life Extension offers a bottle containing 360 capsules. Based on the price per serving, this inositol supplement is the most affordable compared to other products on our list.
Life Extension is also a reliable inositol brand renowned for its 40-year expertise in the market developing science-driven formulations. As the provider claims, this supplement may influence serotonin activity, thus supporting a healthy mood. Nonetheless, more research is needed to determine whether inositol supplementation can support your mood.
Key features of Life Extension inositol
The key supplement factors around Life Extension inositol are the following:
- Inositol amount: 1000 mg of MI.
- Additional ingredients: None.
- Daily dosage: 1 capsule.
- Certificates: cGMP and NSF-certified.
Life Extension inositol for 360 servings is sold at $47.25 ($0.13 per serving).
5. Double Wood — best transparent brand of myo-inositol supplement
Double Wood provides its customers with certificates of analysis and testing results on the product page. This shows the company’s aim to remain transparent regarding the quality of its inositol supplement.
The manufacturer is dedicated to producing single-ingredient products with science-backed formulations and also allowing users to customize their supplement stock. Thus, the brand specifies that this product can be the best myo-inositol supplement for fertility if combined with folic acid.
Key features of Double Wood inositol
Double Wood has the following features:
- Inositol amount: 1000 mg of MI.
- Additional ingredients: None.
- Daily dosage: 2 capsules.
- Certificates: cGMP and NSF-certified.
The triple pack of Double Wood inositol supplements is priced at $44.85 ($0.49 per serving).
6. Natalist — best inositol supplement for versatile use
Natalist Inositol Plus vegetarian capsules contain no added ingredients besides MI and DCI, which allows customers to mix the contents with water in case swallowing capsules is difficult.
This is a well-known and trusted supplement brand that manufactures its products in the U.S. Natalist is also praised for its plastic-neutral and eco-friendly packaging practices.
The provider recommends taking 4 capsules daily or as directed by your doctor. While Inositol Plus contains no major allergens, it is manufactured in a facility that handles milk, nuts, soy, wheat, and shellfish.
Key features of Natalist inositol
- Inositol amount: 2000 mg MI and 50 mg DCI.
- Additional ingredients: None.
- Daily dosage: 4 capsules.
- Certificates: cGMP-certified facilities.
Natalist does not offer a one-time purchase option but rather monthly subscriptions with or without commitment. The delivery every 30 days without commitment is $35 ($1.16 per serving).
7. Femometer — best inositol supplement for PCOS management
Femometer is one of the leading female-oriented companies offering the best myo-inositol and D-chiro-inositol supplements specifically designed to assist in PCOS management and hormone balancing.
Significantly, the provider combined two types of inositol in a 40:1 ratio, which has been shown in studies to potentially support ovulation and egg quality in women with PCOS. The supplement is also gluten-free, 100% vegetarian, and third-party tested.
Key features of Femometer inositol
Femometer Myo- and D-chiro-inositol have the following features:
- Inositol amount: 2000 mg of MI and 50 mg of DCI
- Additional ingredients: None.
- Daily dosage: 3 capsules.
- Certificates: cGMP, ISO, and NSF-certified.
One pack of Femometer inositol costs $35.99 ($1.19 per serving). Also, check out the other two offers by the provider — a pack of 3 bottles and 1 bottle with 50 Luteinizing hormone and 20 HCG tests.
8. Nutricost — best inositol supplement for mood
The manufacturers behind Nutricost offer you one of the best inositol supplements that are gluten-free and vegan and come in easy-to-swallow capsules.
According to the provider, Nutricost inositol is third-party tested, yet no certificate of analysis or test results are published on the official website. Nonetheless, the company offers a 60-day 100% money-back guarantee in case you are not fully satisfied with its inositol quality.
While inositol has been studied for its potential role in mood disorders, a review of scientific studies shows that it lacks beneficial effects for anxiety disorders or other psychiatric disorders. Please note that the claims on the product page may be exaggerated and do not correspond with current scientific knowledge.
Key features of Nutricost inositol
The suggested benefits of Nutricost inositol come with the following features:
- Inositol amount: 500 mg of MI.
- Additional ingredients: None.
- Daily dosage: 1 capsule.
- Certificates: cGMP-certified facilities.
A Nutricost inositol bottle contains 240 servings and comes at an affordable price of $19.95 ($0.08 per serving).
9. BulkSupplements.com — good inositol supplement for health
BulkSupplements.com inositol can be a good addition to your active routine to potentially support weight management, and address certain metabolic risk factors for heart disease.
Although the provider does not specify which inositol type is included in the supplement capsule, it claims it to be gluten-free, vegan, and without unnecessary additives.
If you want to be the first to learn about discounts, you can download the BulkSupplements.com app to your phone for every sale and coupon update.
Key features of BulkSupplements.com inositol
Here are the key factors for you to know when ordering inositol from BulkSupplements.com:
- Inositol amount: 1000 mg.
- Additional ingredients: None.
- Daily dosage: 2 capsules.
- Certificates: NSF, ISO, and cGMP-certified facilities.
You can buy inositol from BulkSupplements.com for 60 servings at $21.96 ($0.36 per serving). Following the link below, you will save up to 18% on your order.
10. GNC — solid inositol supplement brand
GNC, as a vitamin and supplement brand, holds a history dating back to 1935 and has evolved into one of the global retail leaders. One of their hundreds of products is GNC inositol, used widely by the brand’s customers for potential improvement in insulin sensitivity and helping to reduce cravings.
GNC manufacturers designed the supplement as white tablets. The latter does not contain unnecessary additives, is vegan, sugar and starch-free, and is free from major allergens.
Key features of GNC inositol
Learn about the key features of GNC inositol supplement:
- Inositol amount: 500 mg.
- Additional ingredients: None.
- Daily dosage: 1 tablet.
- Certificates: Kosher, cGMP-certified manufacturing.
A one-time purchase of GNC inositol supplement for 100 servings is $19.99 ($0.19 per serving). The monthly subscription will save you 10%, making this another affordable option.
How did we compile the list of best inositol supplements?
To compile the list of the best inositol supplements, we collaborated with the Healthnews research team who selected the top-rated products based on the following quality criteria:
| Formulation | Science-backed |
| Safety | Manufacturing standards and independent testing |
| Brand reputation | Customer reviews |
| Price per serving | $0.08–1.20 |
- Formulation. We selected supplements with different formulations of Myo-inositol (MI) alone or a combination with D-chiro-inositol (DCI). We also included products with various doses to choose from based on the health goals.
- Safety. The inositol supplements on our list have been manufactured in cGMP and FDA-certified sites. We selected products that are free from major allergens and have undergone testing to ensure the absence of contaminants.
- Brand reputation. The brand reputation is built on the transparency of the provider regarding the quality of its products. Customer reviews regarding delivery and transparent communication were also taken into account in our selection process.
- Price per serving. The inositol supplements on our list come at a reasonable price, making them affordable based on the serving size and formulation.
What is inositol?
Inositol is a sugar alcohol naturally found in fruits, beans, nuts, and grains. Inositol is often referred to as vitamin B8, yet it’s not officially recognized as a vitamin. There are 9 forms of this organic compound, Myo- and D-chiro-inositol being the most commonly used forms in supplements.
Inositol has demonstrated certain benefits for cellular processes, particularly cell growth and development. It is suggested to work by regulating insulin sensitivity, influencing glucose metabolism and hormonal balance.
Myo-inositol and D-chiro-inositol are widely used for managing conditions such as polycystic ovary syndrome (PCOS) and some other metabolic disorders. However, more research on inositol effects and safety is needed.
What research says about the benefits of inositol
Inositol has been observed in a number of studies for its potential benefits. Although more profound and longitudinal studies are needed to look into inositol safety and long-term use, the following is what science revealed regarding its benefits:
- Mood support. Although inositol has been found to play a role in the pathogenesis of mood disorders, administration of inositol did not lead to improvement of psychiatric disorders. While the evidence is limited to a small number of studies, currently, inositol cannot be recommended for mood disorders.
- Improved sleep. While additional research is required to look into the direct effects of inositol on sleep, current evidence hints at a potential connection between this sugar-alcohol compound and enhanced sleep quality in pregnant women.
- Fertility enhancement. Extensive studies have focused on inositol, particularly myo-inositol, examining its impact on fertility in women facing challenges with conception. Myo-inositol has been associated with hormonal balance, enhanced insulin sensitivity, the promotion of ovulation, and an increased rate of pregnancies.
- Weight management. Myo- and D-chiro-inositol have demonstrated potential benefits for weight management in adults and especially in women with PCOS. Inositol is believed to enhance fat and carbohydrate metabolism by improving insulin sensitivity, particularly for those with insulin resistance.
It’s essential to remember that these effects may vary from person to person and depending on the doses. It's advisable to discuss doses, duration, and your individual health circumstances with your healthcare provider.
Type of Inositol: D-chiro-inositol vs. Myo-inositol
Inositol is the general name of 9 types or stereoisomers of the compound, out of which Myo-inositol and D-chiro-inositol are the most bioactive ones and commonly used in supplements. Although both of them may have similar benefits for the body, they may also differ in the following characteristics:
- Chemical structure. These two forms of the compound have a fairly similar chemical structure with minor differences in the atomic arrangement, which may influence how it interacts with your body.
- Presence in the body. The human body is naturally abundant in Myo-inositol in comparison to D-chiro-inositol.
- Benefits. Both of these types of inositol may be involved in PCOS symptom reduction, enhanced insulin sensitivity, hormonal balance, and weight management, especially for women with overweight or obesity and individuals with PCOS.
- Use in supplements. Myo-inositol is more often used alone in supplement formulations or in combination with D-chiro-inositol. The latter, on the other hand, is less often used as a standalone supplement.
How to pick the right inositol supplement for your health needs?
Choosing the right inositol supplement should begin with talking to your healthcare provider for personalized advice based on health goals and concerns. Following the doctor’s recommendations, opt for inositol supplements according to the following factors.
Capsules vs. powder
Identify if you are more comfortable supplementing with inositol capsules or proceeding with powder. The only difference between these forms is the method of administration.
If inositol powder comes in sachets with pre-measured doses, you can easily dissolve it into water and drink, yet with bulk powder, it may be hard to measure the exact doses.
Inositol may have a slightly sweet taste, which may not be palatable for some. Capsules, on the other hand, may be tasteless alternatives to powder.
Formulation
Talk to your doctor to specify the formulation of the supplement, whether Myo-inositol alone suffices or if a combination with D-chiro-inositol is more suitable. You may also identify if the inclusion of other active ingredients, such as folic acid, magnesium, and others, is required based on your health goals.
Dosage
Your doctor can help you choose the right inositol supplements for you in the suitable and safest dosage in accordance with your health needs. The recommended doses may vary depending on whether you are aiming for metabolic support, want to regulate menstrual cycles or improve ovary function for successful conception.
Possible interactions
In case you are taking any medications, talk to your doctor to make sure there is no risk of negative interaction. Inositol may also be advised not to be used in case of certain medical conditions.
Inositol may interact with some medications and may also be advised not to be used in case of specific medical conditions. Thus, talking to your doctor is essential to obtain guidance based on your health status and use of certain medications.
Who should not take inositol?
Inositol is considered generally safe for most adults. Nonetheless, some people with possible allergic reactions or known health conditions may be advised not to use inositol supplements.
Although there are some studies where inositol has been used among pregnant and breastfeeding women, its use in these conditions should be consulted with a doctor.
People using blood sugar-reducing medications should also consult with their doctor prior to supplementation to avoid hypoglycemia (extremely low blood sugar levels).
Women with PCOS are often recommended inositol supplementation. Yet, not all women living with PCOS may benefit from it due to individual responses and the varying manifestations of this health condition.
Best inositol supplement: conclusion
Summarizing what was written above, we can conclude that inositol may be a therapeutic means for addressing a number of health challenges, including high blood sugar levels, high blood pressure, and other metabolic risk factors, as well as PCOS.
Despite the emerging scientific evidence, it’s essential to acknowledge the need for further research for a profound understanding of inositol safety and efficacy. Thus, for more comprehensive guidance, you should consult your healthcare provider before buying any product from our list of the best inositol supplements.
Discover other supplements to implement into your routine
Check out our selection of the best fertility supplements for women.
When seeking natural formulas for relaxation, consider ashwagandha supplements.
Enhance your performance with the best energy supplements.
Complement your workouts with the best supplements for muscle growth.
FAQ
What is an inositol supplement used for?
The primary use of inositol is for its potential benefits in metabolic health and managing PCOS symptoms. Although some studies have examined the potential role of inositol in mood disorders, the scientific evidence does not support its use for managing mental health conditions.
Is it good to take inositol every day?
It depends. Inositol is generally safe to take every day for up to 6 months, as used in some research studies with no or minimal side effects, yet the administration should be discussed with your healthcare provider.
What is the best time to take inositol?
Although inositol is often recommended to be taken in the morning on an empty stomach for optimal absorption, studies show that it may be consumed on both empty and full stomach with similar efficacy.
Does inositol reduce belly fat?
Inositol, particularly myo-inositol, may have weight-reducing effects through improved insulin sensitivity and metabolism. Yet, more studies are needed to establish inositol’s direct effectiveness in belly fat reduction.
What does inositol do to hormones?
Inositol has been shown in studies to play a role in supporting insulin sensitivity and potentially balancing blood sugar levels. Inositol has been studied for its hormone-balancing benefits in PCOS and menstrual regulation.
6 resources
- Open Heart. Myo-inositol for insulin resistance, metabolic syndrome, polycystic ovary syndrome and gestational diabetes.
- Reproductive Biology and Endocrinology. Inositol is an effective and safe treatment in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials.
- Journal of Medicinal Food. Influence of Concomitant Food Intake on the Excretion of Orally Administered myo-Inositol Hexaphosphate in Humans.
- Current Issues in Molecular Biology. Neurobiology and Applications of Inositol in Psychiatry: A Narrative Review.
- The Journal of Maternal-Fetal & Neonatal Medicine. The impact of myo-inositol supplementation on sleep quality in pregnant women: a randomized, double-blind, placebo-controlled study.
- Pharmaceuticals. Myo-Inositol as a Key Supporter of Fertility and Physiological Gestation.
- Inositol amount: 4Additional ingredients: Magnesium citrate.000 mg MI and 100 mg DCI.
Your email will not be published. All fields are required.