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The Ultimate Guide to the Best Liquid Probiotic (2024)

Probiotics have gained significant popularity in recent years.

The global probiotics market was estimated at USD 77.12 billion in 2022 and is expected to grow at a compound annual growth rate (CAGR) of 14.0% from 2023 to 2030.

The liquid probiotics segment is on the rise in the market, driven by the increasing demand for probiotic-filled beverages, milk, yogurt-based drinks, and juices, as well as the growing awareness of the importance of gut health support.

With numerous options available on the market, it can take time to identify the best liquid probiotics.

This guide provides a comprehensive overview of the best liquid probiotic supplements, highlighting their key features and customer feedback. We also explore what liquid probiotics are, how to use them effectively, and the potential side effects and considerations to keep in mind.

Best liquid probiotic supplements: a shortlist

Before diving into the details, let’s highlight some of the best liquid probiotics available:

  1. SCD Probiotics — best liquid probiotic supplement for adults
  2. SCD Probiotics Immunity — best liquid probiotic supplement for immune health support
  3. Mary Ruth's — best liquid probiotic drops for adults
  4. Healthy Genetics — best affordable liquid probiotic supplement
  5. VitaGut — best liquid probiotic supplement in a glass bottle

How we compiled our list of the best liquid probiotic supplements

To compile our list of the best liquid probiotic supplements, we carefully evaluated a range of products based on several key criteria:

CFU countStrain diversityAdditional ingredientsQuality certificationsUser reviewsPrice
1–50 billion8–13 probiotic strains No unnecessary fillers or additivesGMP, USDA Organic, clean label PROJECT, and othersCustomer feedback$17.95–59.95
  • CFU count. We assessed each product's colony-forming unit (CFU) count per serving.
  • Strain diversity. We favored liquid probiotics that contained a diverse array of probiotic strains.
  • Additional ingredients. We examined the supplement facts panel to ensure that the liquid probiotics did not contain unnecessary additives or fillers.
  • Quality certifications. We considered certifications such as Good Manufacturing Practices (GMP) and third-party testing. These certifications ensure consistent quality and adherence to manufacturing standards.
  • User reviews. We looked at user reviews to gauge customer satisfaction and reported observed benefits, and side effects.
  • Price. We prioritized products that offer good value for money.

Best liquid probiotics: an overview

Here, we introduce you to some of the top liquid probiotic products available today. We'll provide a detailed look at each product, including their general features and what customers love and don’t like. Each review will end with our verdict based on the product information and customer feedback.

Let’s start!

1. SCD Probiotics — best liquid probiotic supplement for adults

SCD Essential Probiotics

SCD Essential Probiotics is a liquid probiotic supplement that contains 11 live strains, including strains from Lactobacillus, Bacillus, and Saccharomyces genera. It is non-GMO, vegan, and free from artificial additives.

Key features:
11 live probiotic strains, 3 and 16.3 fl. oz options, 32-day supply (for 16.3 fl. oz bottle)

This supplement has an Amazon rating of 4.2/5 stars based on 551 reviews. Many users report experiencing reduced bloating and a more regular bowel function after taking SCD Essential Probiotics. However, some customers have noted a slightly unpleasant taste, which may be a consideration for some.

The provider recommends mixing one tablespoon with water, juice, or a smoothie once daily for adults and children over 12 years and one teaspoon for children aged 2 to 12.

A 16.3 fl. oz bottle with 32 servings costs $31.98 for a one-time purchase.

In our view, this may be an excellent liquid probiotic option as it offers good value for price.

2. SCD Probiotics Immunity — best liquid probiotic supplement for immune health

SCD Probiotics Xtra Immunity

SCD Probiotics Xtra Immunity is designed to support immune function. It is made with a combination of organic brown rice, organic rice bran, papaya, and organic kelp, which are fermented to create a rich source of enzymes, antioxidants, vitamins, amino acids, minerals, and other bioactive substances, as the company claims.

Key features:
Natural ingredients, 33-day supply.

On Amazon, this product has a rating of 3.9/5 stars based on 12 reviews. Buyers appreciate the formulation for immune system support, although some customers complain about the price.

The manufacturer recommends that adults take 1–3 tablespoons daily, either alone or mixed with a favorite drink.

The fee for one bottle with 33 servings is $59.95.

We think the product may benefit immune function support due to the choice of its fermented natural ingredients.

3. Mary Ruth's — best liquid probiotic drops for adults

MaryRuth Organics Liquid Probiotic

Mary Ruth’s Organic Liquid Probiotic is formulated to support gut health. It contains 13 probiotic strains, including Bacillus coagulans, Lactobacillus acidophilus, L. rhamnosus, and L. plantarum, which are clinically studied strains. This proprietary probiotic blend contains up to 2 billion CFU per serving.

Key features:
13 strains, USDA Organic, vegan, non-GMO, unflavored, up to 160 servings

With an Amazon rating of 4.3/5 stars from 12,129 reviews, users like the quality and mention that this product helped to improve their digestive function. But many users don’t like that the new formula is oil-based.

The brand recommends that adults take 3 mL or 60 drops/4 pumps of the liquid probiotic daily.

A 120 mL bottle of this product costs $44.95.

In our opinion, this may be a good liquid probiotic option, standing out due to its good quality.

4. Healthy Genetics — best budget-friendly liquid probiotic supplement

Healthy Genetics Liquid Probiotics

Healthy Genetics Organic Liquid Probiotics is an all-natural and plant-based probiotic supplement made to support digestion and immunity. The product contains 12 live probiotic strains, including Lactobacillus and Bifidobacterium strains, with 75 mg of ginger root added.

Key features:
Organic, Plant-based, 12 live strains, 2 oz/60ml, 30 servings.

On Amazon, this liquid probiotic has a rating of 4.3/5 stars based on 842 reviews. Customers like the product’s quality and say it works well for digestive issues. While many buyers are satisfied with the taste, a fraction are not fans.

Healthy Genetics recommends taking two ½ droppers (2 mL) daily.

The price for one bottle with 30 servings is $17.95.

We think that the product may be a good liquid probiotic choice due to its probiotic strain diversity and positive user feedback.

5. VitaGut — best probiotic in a glass bottle

VITAGUT Liquid Probiotic

VitaGut Liquid Probiotic is a 3-in-1 supplement that combines probiotics, prebiotics, and postbiotics. It boasts 50 billion CFU and contains 19 fermented botanicals aimed at digestive health support. The probiotic blend includes eight beneficial bacteria strains, including Lactobacillus and Bifidobacterium cultures.

Key features:
8 live bacteria cultures, organic, 50 billion CFU, 19 fermented herbs, 32 servings.

This product has an Amazon rating of 4.3/5 stars based on 135 reviews. Users appreciate the natural ingredients and say that it helps their stomachs feel better. Some users, however, mentioned that it made them feel gassy.

The company recommends taking 1–2 tablespoons daily.

One bottle with 32 servings is priced at $29.95.

In our view, this may be a beneficial product for digestion support as it is formulated with quality ingredients.

Comparing the best liquid probiotic supplements

Here is a quick comparison of the top liquid probiotic supplements.

BrandPriceServing size (adults)Servings per container (adult)No. of probiotic strainsCertifications
SCD Probiotics$31.98*1 tablespoon (15 mL)3211Certified organic
SCD Probiotics Immunity$59.951 tablespoon33N/ANot specified
Mary Ruth's$44.953 mL4013USDA Organic, B-Corp, Clean Label Project
Healthy Genetics$17.952 mL3012Not specified
VitaGut$29.951 tablespoon328USDA Organic, GMP

* — price may vary based on size

What are liquid probiotics?

According to a publication from the Food and Agriculture Organization of the United Nations and World Health Organization (WHO), probiotics are defined as "live microorganisms which, when administered in adequate amounts, confer a health benefit on the host."

Liquid probiotics are dietary supplements containing live beneficial bacteria suspended in a fluid medium. They typically contain beneficial bacteria strains from Lactobacillus or Bifidobacterium genera, which are two of the most clinically studied probiotic genera. These strains are proposed to help support digestive and immune health.

These types of supplements may offer ease of use as they can be consumed directly or added to food and beverages.

However, liquid probiotics often have shorter shelf lives and may require refrigeration to maintain viability. The concentration of probiotic organisms can vary, making exact dosage information challenging, especially in traditional fermented drinks.

Health benefits of liquid probiotic supplements

Research studies specific to the benefits of liquid probiotics are lacking. However, several studies have highlighted potential health benefits associated with the regular consumption of probiotics in general.

Here are four of those benefits.

May improve digestive health

Liquid probiotics may help ease digestive symptoms in conditions like irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD).

A 2022 review found that probiotics, particularly those containing Bifidobacterium and Lactobacillus strains, reduced abdominal pain, flatulence, and other associated symptoms in individuals with IBS. This means that taking liquid probiotics might help you feel more comfortable if you have digestive problems.

May support immune function

Evidence suggests that intestinal immune cells actively use bacterial microflora in the gut, potentially improving immune homeostasis. Probiotics stimulate cytokine and chemokine production in immune cells and activate IgA-producing cells, enhancing mucosal immunity.

These immunomodulatory effects may contribute to the management of immune-related diseases, including inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), inflammation, diarrhea, and pathogenic infections.

May help with Antibiotic-Associated Diarrhea (AAD)

Antimicrobial therapy disrupts the natural gut microbiota, often leading to diarrhea. In most cases, this diarrhea is associated with an overgrowth of Clostridioides difficile, resulting in C. difficile–associated diarrhea (CDAD).

Recent clinical studies have examined the effectiveness of probiotics, particularly the strain Lactobacillus GG and the yeast strain S. boulardii, in reducing the risk of and managing CDAD. Systematic reviews with meta-analyses confirm the efficacy of these probiotics in reducing the risk of AAD.

However, it is not recommended to use probiotics to treat AAD as there is not enough available data from randomized controlled trials, and the effectiveness and safety of such treatment are not well understood.

May support mental health

Changes in the gut microbiome are proposed to affect cognitive and psychological functions via the microbiota–gut–brain (MGB) axis. Probiotic supplements are thought to have positive effects on mental health when taken in sufficient amounts.

Human clinical trials consistently demonstrate that probiotic therapies yield positive mental health effects. For example, a combination of L. helveticus and B. longum probiotics reduced psychological distress in healthy volunteers over one month. In addition, individuals who consumed a daily milk drink containing probiotics experienced a notable mood improvement after three weeks compared to a placebo.

How to use liquid probiotics effectively

  • Dosage instructions. Try to adhere to the recommended dosage provided by the manufacturer. Typically, this is 1-2 tablespoons daily for adults, but it can vary between products.
  • Mixing with other fluids. Liquid probiotics can be consumed directly or mixed with water, juice, or smoothies. Avoid adding them to hot drinks, as high temperatures can kill the live bacteria.
  • Storage. Liquid probiotics should be stored in a cool and dark place and refrigerated after opening (for those requiring refrigeration). Proper storage is crucial to maintaining the viability of the live bacteria.
  • Handling. Before each use, shake the bottle well to ensure the bacteria are evenly distributed throughout the liquid.
  • Avoiding overdosing. Taking more than advised will not necessarily increase benefits and could lead to digestive discomfort.

Potential side effects and considerations of liquid probiotics

Liquid probiotics are generally safe for most people. However, there are some potential side effects and considerations to keep in mind. These include:

  • Initial digestive discomfort. Some individuals may experience mild digestive side effects, such as bloating, gas, or diarrhea when first starting probiotics. These symptoms are usually temporary and should subside as your body adjusts to the new bacteria.
  • Immune system considerations. If you have a compromised immune system or underlying health conditions, it's essential to approach probiotics with care. Consulting with a healthcare provider can help ensure that probiotics are safe and suitable for you.
  • Interaction with medications. Probiotics can interact with certain medications, such as antibiotics. Taking probiotics and antibiotics at least two hours apart is advisable to prevent the antibiotics from killing the beneficial bacteria. Consider discussing potential interactions with your healthcare provider.

Best liquid probiotics – conclusion

The best liquid probiotics are characterized by high-quality, non-GMO, and organic ingredients, diverse bacterial strains, and formulations that protect the viability of the beneficial bacteria.

Our best picks stand out due to their ease of use and positive customer feedback.

While liquid probiotics are generally safe for most people, it is crucial to be mindful of potential side effects and to consider consulting with a healthcare provider if you have underlying health conditions or are on medications.


Dive into our other probiotic resources

Check out the best-rated probiotics for gut health and digestion.

Discover the best probiotics for kids to support optimal gut function.

Explore some of the best probiotics for women to combat digestive issues.

Find out the best probiotics for IBS to support the intestinal barrier.


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