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Best Nootropic Stack in 2024: Choose The Top Nootropic Blends

In 2024, the field of nootropics has seen remarkable advancements, with an array of cutting-edge cognitive enhancers flooding the market. We present a comprehensive review of the best nootropics in the market.

This article aims to guide readers in selecting the best nootropic stack for optimal cognitive performance and mental clarity. Each brand offers unique formulations, combining science-backed ingredients to boost focus, memory, and overall brain function.

Whether you are a student, professional, or just seeking a mental edge, this comprehensive guide will help you make an informed choice for improved cognitive enhancement.

Best nootropic stack: shortlist

  1. Hunter Focus — overall best nootropic stack
  2. NooCube — best nootropic for memory and fighting “screen fatigue”
  3. Oweli Neuro — best nootropic blend for memory, learning, and overall brain health
  4. Nooceptin best nootropic for learning, memory, and mood
  5. Vyvamind — best nootropic for focus, concentration, and reaction speed

How to choose the best nootropic stack in 2024?

To make an informed choice and find the most effective nootropic stack for cognitive enhancement in 2024, consider the following key criteria: ingredient quality, brand reputation, dosage and efficacy, stimulant content, and value for money.

Ingredient qualitySafe, clearly disclosed, and premium ingredients
Brand reputationEstablished and trusted brands
Dosage and efficacyScience-backed ingredients at the right amounts
Stimulant contentProvide focus and alertness without excessive stimulants
Value for moneyOptimal blend of quality and affordability
  • Ingredient quality. Ensure the nootropic blend contains high-quality, scientifically-backed ingredients without unnecessary fillers or additives. Look for products with transparent labeling, indicating the exact composition and dosages of each ingredient.
  • Brand reputation. Choose stacks from reputable providers with a history of producing safe and effective supplements. Research the brand's track record, customer reviews, and commitment to quality to ensure reliability.
  • Dosage and efficacy. Check that the stack offers adequate dosages of each ingredient to deliver noticeable cognitive benefits. It should be formulated to promote synergy among the components for optimal brain function.
  • Stimulant content. Avoid stacks containing excessive stimulants, as they may lead to jitters, anxiety, or sleep disturbances. Look for balanced formulations that enhance focus and alertness without overstimulation.
  • Value for money. Consider the price relative to the quality and quantity of ingredients. A cost-effective stack offers a good balance between price and cognitive benefits, making it accessible to a broader range of users seeking improved brain health in 2024.

Best nootropic stack in 2024: overview

Nootropic stacks, combinations of different cognitive-enhancing compounds, have gained popularity due to their synergistic effects and potential to target multiple aspects of brain function.

Here's an overview of some of the best nootropic blends that have garnered attention in 2024:

1. Hunter Focus — overall best nootropic


Hunter Evolve Focus is a formula with 20 ingredients wherein the company features three core areas where the product may help with:

  • Concentration activation: (citicoline, L-tyrosine, L-theanine, Ginkgo biloba, Spanish sage extract).
  • Memory matrix: (lion’s mane mushroom, Bacopa monnieri, Rhodiola rosea).
  • Mood amplification: (phosphatidylserine, ashwagandha root, caffeine anhydrous, Panax ginseng).

In addition to these three core areas, clinical studies also demonstrate further benefits from some of their ingredients including enhanced memory, improved attention, stress relief, greater focus, elevated mood, increased energy, boosted creativity, and optimized learning.

Additionally, this product also contains vitamins (B6, B9, B12, C, D3, K2), acetyl-L-carnitine, and maritime pine bark extract which adds further benefits associated with these ingredients.

2. NooCube — best nootropic for memory, fighting “screen fatigue”


NooCube Brain Productivity has 13 ingredients: LuteMax (proprietary blend of 3 carotenoids), Bacopa monnieri, Huperzia serrata, pterostilbene, resveratrol, L-theanine, L-tyrosine, alpha-GPC (glycerylphosphorylcholine), oat straw extract, cat’s claw extract, and B-group vitamins (B1, B7, and B12).

From their website, NooCube suggests that their daily nootropic formula may help to have sharp focus, boost memory, increase attention, lessen stress and brain drain, and promote eye-brain connectivity to combat mental fatigue and “screen fatigue.”

One unique feature of NooCube is the inclusion of LuteMax, a patented combination of lutein and zeaxanthins that was tested in a 12-month clinical study and was shown to help with memory, comprehension, and visual acuity.

Their inclusion of this formula was due to the findings in Journal of Aging Research in 2013 that showed that older people that maintained normal cognitive functions late in life had higher macular carotenoid levels (lutein and zeaxanthin) in certain brain regions involved in processing information.

3. Oweli Neuro — best nootropic for memory, learning, overall brain health

Oweli Neuro-comm

On top of additional vitamins, minerals, and other organic compounds/extracts, Oweli Neuro highlights 8 major ingredients: phosphatidylserine, huperzine A, Bacopa monnieri, B vitamins (B6, B9, B12), DMAE (dimethylethanolamine), inositol, N-acetyl L-tyrosine, and zinc. It is third-party tested and the certificates are available upon request.

Overall, the purported benefits of Oweli Neuro include boosting cognitive function, promoting memory recall, fighting stress, promoting a better mood, optimizing productivity, and supporting concentration, which are all suggested to be achieved through the potential synergistic interactions of the ingredients.

However, although the potential benefits of individual active ingredients for cognitive and mood support have been studied, their interactions have not. Future research should ascertain the synergistic interactions or side effects of the exact formulation.

4. Vyvamind — best nootropic for focus, concentration, reaction speed


Vyvamind Neurostimulant + Focus Aid contains 6 ingredients: vitamin B6 and B12, L-tyrosine, citicoline, L-theanine, and caffeine anhydrous. It is third-party tested and the certificates are available upon request.

According to the website, Vyvamind's key benefits are focus, memory, and concentration. Specifically, they claim that the product may potentially help enhance focus and clarity, increase your motivation and drive, support against stress and anxiety, promote faster thinking, and protect against mental fatigue and burnout.

In addition to suggested improvement in memory, visual tracking, and reaction speed tests, they further indicate that Vyvamind formulation has been clinically proven to increase brain energy by 14% and cell membrane formation by 26%; however, the exact research studies or data are not available on their website.

5. Nooceptin — best nootropic for learning, memory, mood


NooCeptin Advanced Nootropic Formula includes 7 ingredients: lion’s mane extract, citicoline, L-theanine, Panax ginseng extract, Rhodiola rosea extract, Bacopa monnieri extract, Ginkgo biloba extract. It is third-party tested and the certificates are available upon request.

Nooceptin suggests that their product may help in specific cellular processes to promote cognitive enhancement, such as neurotransmitter production, neuron growth and maintenance, dendrite growth, stress control, and brain cell protection. The evidence for some of these benefits comes from cell and animal studies, thus it is yet to be demonstrated if these exact mechanisms are successfully induced in humans.

Additionally, they note that it may help you feel more motivated and driven to complete a task, multitask more effectively and with enhanced working memory, make quicker decisions, concentrate for prolonged periods of time without a break, process complex information faster, and get protected from stress-induced brain fog.

Comparison of the top 5 nootropic stack brands

Here is a summary table to help you choose the right nootropic supplement based on the price per bottle (1-month supply), serving size, total ingredients, caffeine content, transparency of composition, and information about third party testing.

BrandReviewScience-backed ingredientsPrice per bottleCapsules in a bottleServing sizePrice per servingTotal ingredientsCaffeine ContentTransparencyThird party testing
Hunter FocusHunter Focus reviewYes€75.00 1806 capsules€2.5020Yes (100 mg)Fully disclosed formulaNot publicly available
NooCube reviewYes$79.99 602 capsules$2.6613NoIncludes a proprietary blend (LuteMax 2020)Yes
Oweli NeuroOweli Neuro reviewYes$29.99 602 capsules$0.998+NoIncludes a proprietary blendAvailable upon request
NooCeptinNooceptin reviewYes$77 903 capsules$2.567NoFully disclosed formulaAvailable upon request
Vyvamind reviewYes$80 601 capsules$1.336Yes (75 mg)Fully disclosed formulaAvailable upon request

How we compiled our list of the best nootropic stacks in 2024

Our list of the best nootropic stacks in 2024 was compiled through a rigorous and comprehensive process, taking into account the following factors:

  • Brand Reputation. We assessed each brand's reputation based on its history, transparency, and commitment to quality and customer satisfaction.
  • Ingredients. Extensive research was conducted to evaluate the efficacy, safety, and scientific evidence supporting the nootropic stack's ingredients.
  • Customer Reviews. Real customer reviews and feedback were analyzed to gauge the actual experiences and results of users with each nootropic stack.
  • Dosage. We considered the dosages of individual ingredients in the stack to ensure they were effective and within safe limits.
  • Price. The cost-effectiveness of each nootropic stack was evaluated, considering the quality and quantity of ingredients offered in relation to the price.

Through this meticulous process, we identified the top nootropic stacks that offer the best combination of brand reputation, science-backed ingredients, positive customer reviews, appropriate dosages, and reasonable pricing for users seeking cognitive enhancement in 2024.

How to stack nootropic ingredients?

Nootropic stacking involves combining multiple cognitive-enhancing ingredients to achieve synergistic effects and optimize brain function.

To create an effective nootropic stack, follow these steps:

  1. Start by researching the individual effects and potential interactions of each supplement.
  2. Begin with a simple combination of well-known and well-tolerated nootropics before gradually adding others.
  3. Pay attention to dosages, avoiding excessive amounts to prevent adverse effects.
  4. Consider your personalized needs and goals, and always consult a healthcare professional if you have pre-existing medical conditions or are taking other medications.
  5. Track the effects of the stack and be open to adjustments to find the most effective and safe combination for enhanced cognitive performance and overall well-being.

Consult with a healthcare professional for the best advice suitable for yourself and your goals, especially if you have medical conditions or take other medications. Remember, nootropics are not a substitute for a healthy lifestyle, sleep, and proper nutrition. Always prioritize safety and individual tolerance when experimenting with nootropic stacks.

What ingredients to look out for in nootropic stacks

When building an effective nootropic stack, it is crucial to select ingredients with scientifically-backed cognitive-enhancing properties. Below are some key ingredients to look out for, each offering unique benefits to boost mental clarity and brain function.

Bacopa monnieri

Bacopa monnieri is a herb used in Ayurvedic medicine for centuries to improve memory and cognitive function. Experimental studies suggest that it potentially works by increasing the production of acetylcholine, a neurotransmitter that is essential for memory and learning.

In addition, Bacopa monnieri is a well-researched nootropic thought to have neuroprotective effects as well. It may help to delay the onset of Alzheimer's disease according to in vitro and animal studies, but human studies are limited.

Ginkgo biloba

Ginkgo biloba is a tree and its extract has been shown to improve memory, focus, and cognitive function. It works by increasing blood flow to the brain and by improving the production of neurotransmitters, particularly acetylcholine.

Ginkgo biloba is a nootropic particularly popular in improving memory and focus. Because of this, it is also suggested that it may help to protect against dementia; however, human clinical studies are also limited.

Lion’s mane mushroom

Lion's mane mushroom extract has been shown to improve memory, learning, and cognitive function. As animal and cell studies suggest, it may work by stimulating the growth of new brain cells and by increasing the production of nerve growth factor (NGF), a protein that is essential for brain and neuron health.

As one of the currently most popular brain health supplements, Lion's mane extract is a promising nootropic due to its effects on brain cells leading to improved cognitive functions. Although it has been suggested that it may help to protect against neurodegenerative diseases, most evidence of lion's mane neuroprotective properties comes from animal and cell studies. More studies are needed to establish the neuroprotective benefits and long-term safety of lion's mane extract in humans.

Rhodiola rosea

Recognized as an adaptogen, Rhodiola rosea extract contains natural substances that may increase the body's resistance to stress in non-specific ways. Research shows that this herb may improve cognitive function, reduce stress, and boost energy levels. It potentially works by increasing stress resistance and improving the production of crucial neurotransmitters including dopamine and norepinephrine.

Additionally, Rhodiola rosea has also been shown to have neuroprotective properties, especially in people who are experiencing stress-related cognitive decline.


Derived from green tea, L-theanine is an amino acid that has been shown to improve focus, concentration, and reduce anxiety. Studies suggest that it works by increasing the production of gamma-aminobutyric acid (GABA), a neurotransmitter that promotes relaxation.

L-theanine is a natural calming agent that can help to improve focus and concentration without causing drowsiness. It is often combined with caffeine to create a synergistic effect, with the caffeine providing energy and the L-theanine reducing the negative side effects of caffeine such as anxiety and jitters.

Can nootropic stacks help improve sleep?

Scientific evidence on the direct sleep-improving effects of nootropic stacks is limited. While some nootropics stacks with magnesium, ashwagandha, Rhodiola rosea, may have calming, relaxing, or anti-stress and anti-anxiety properties, their impact on sleep varies individually.

More accurately, nootropic stacks primarily target cognitive enhancement rather than sleep regulation. If sleep improvement is the goal, it is best to focus on specific sleep-promoting supplements. Sleep is a complex process, and relying solely on nootropic stacks for sleep enhancement may not yield the expected results. Moreover, some nootropic stacks contain caffeine which can negatively affect the latency, duration, and quality of your sleep.

Can you overdose on nootropics?

Yes, it is possible to overdose on nootropics. While nootropics are generally considered safe at recommended doses, excessive consumption can lead to adverse effects.

Overdosing on certain nootropics may cause symptoms like increased heart rate, headaches, nausea, anxiety, or digestive issues. Additionally, combining multiple nootropics or taking them with other medications can heighten the risk of adverse reactions. It's crucial to follow recommended dosages and consult a healthcare professional before using nootropics, especially if you have pre-existing medical conditions or are taking other medications, to avoid potential overdose and ensure your safety.

The supplements in this list should not be used by individuals under the age of 18, or by nursing and breastfeeding individuals.

Read more about nootropic supplements and their benefits

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Best nootropics for ADHD: find the top nootropic stacks that improve learning, concentration and are suitable for ADHD symptoms management.

Best nootropics for studying: learn what nootropic ingredient stacks might help tackle cognitively demanding tasks

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