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5 Best Nootropics for ADHD 2024: Over-the-counter Nootropics Reviewed

Nootropics are natural or synthetic substances that could boost your cognitive function, learning, and memory.

Also known as “smart drugs,” nootropics may be one of the best options for people looking for better concentration and learning abilities. These brain-boosting properties of nootropic supplements may be enticing for people with ADHD.

To ease the process of selecting brain supplements, we handpicked the 5 top-rated nootropics on the market and evaluated their efficacy, safety, and benefits to help address ADHD symptoms.

Best nootropic for ADHD: shortlist

  1. NooCube — best ADHD nootropic for visual memory
  2. Mind Vitality — best nootropic to support focus in ADHD
  3. Onnit — best nootropic for ADHD without caffeine
  4. Performance Lab — best ADHD nootropic with minimal ingredients
  5. Vyvamind — best nootropic for ADHD and enhanced performance

How to choose the best nootropics for ADHD?

When it comes to choosing the best nootropic for managing ADHD, you should try to find a supplement formulated with science-backed ingredients and corresponding safety guidelines.

Although every human brain is unique, we differentiated specific criteria that should be universal when picking the best supplements for your needs.

Clean and science-backed
QualityTesting and certification
ManufacturingcGMP and FDA-compliant
Price per serving$1.50–$2.50
  • Ingredients. Look for natural nootropics for ADHD composed of clean ingredients. Make sure each ingredient is suitable for use in case of ADHD. Also, search for scientific evidence vouching for the efficacy of the ingredients.
  • Quality. Companies may assure the quality of nootropic supplements through third-party testing. This refers to the quality and purity testing by independent labs for the absence of toxic compounds.
  • Manufacturing. The highest quality nootropic stacks for ADHD should be developed in FDA-approved sites following the Current Good Manufacturing Practices (cGMP). This type of manufacturing aims to maintain supplements' safety by avoiding contaminants.
  • Price per serving. We specify an approximate price range you should look for when buying nootropics. The number of ingredients shouldn’t play a role in increased costs.

Best nootropics for ADHD in 2024: overview

Referring to the abovementioned criteria, we created our list of the best nootropics to manage ADHD.

It’s worth noting that some of them are nootropic stacks for ADHD that contain more than 10 active ingredients, including vitamins, minerals, and herbal extracts.

Below is a detailed description of over-the-counter nootropics for ADHD and how they may help with focus and anxiety.

1. NooCube — best ADHD nootropic for visual memory


NooCube emerges as a 12-ingredient nootropic stack for ADHD and visual memory which contains an award-winning complex of lutein and zeaxanthin.

Most recent studies, during which younger adults followed a 6-month supplementation routine with these two carotenoids, showed higher visual memory and learning scores. No adverse effects were reported with the extended usage.

It has been proposed in a recent review that ADHD is a potential risk factor in the development of neurodegenerative diseases later in life. With this in mind, NooCube included two potent antioxidants proven to play a role in neuroprotection while aging resveratrol and pterostilbene.

NooCube may not be suitable for vegans and people with allergies as it contains gelatin capsules, soy, cereals, and gluten.

Active ingredients

NooCube incorporates 12 natural ingredients, and below are some of them.

Vitamin B7: Vitamin B7 was shown in animal studies to be helpful in the prevention of neuropathic pain by reducing inflammation. Also, it’s involved in pathways promoting neuron survival and plasticity.

Choline: Choline is a so-called precursor for acetylcholine which is a neurotransmitter responsible for memory, learning, focus, and motor functions.

Cat’s claw: It has been found to reduce the accumulation of brain plaques (associated with aging and Alzheimer's disease) and improve short-term memory. However, the limited research is coming from animal studies, thus, its applicability to human research is yet to be established. One should consult their doctor before supplementation if they have an autoimmune disease.

A bottle of NooCube containing 60 capsules for 30 servings is sold at $64.99 ($2.16 per serving).

2. Mind Vitality — best nootropic to support focus in ADHD

Mind Vitality Focus

Mind Vitality Focus nootropic is a so-called ‘Ignition Tri-Factor’ aimed at lowering stress, boosting focus, and maximizing cognitive function in people with or without ADHD.

This nootropic capsule contains natural adaptogens and brain vitamins, making the Mind Vitality formula suitable for people with ADHD looking for potential stress relief for focus, mental clarity, and brain health.

Mind Vitality Focus is non-GMO, soy-free, and vegan. As per the provider's guidance, this nootropic is known for boosting brain energy, and it's advisable to take it well in advance of bedtime.

Active ingredients

Mind Vitality contains 17 ingredients. The addition and benefits of each are science-backed, according to the provider. Here are some of the most significant of them.

Lion’s mane: The evidence regarding the neuro-enhancing effects of lion’s mane mushrooms is limited. Yet, some evidence sheds light on their potential mood and focus-enhancing properties.

Ashwagandha: Ashwagandha may be a solid adaptogen for ADHD and anxiety. This ayurvedic herb has been found to improve sleep, self-reported mood, and anxiety.

You can get your monthly supply of Mind Vitality Focus nootropic at the cost of $69.99 ($2.33 per serving).

3. Onnit — best nootropic for ADHD without caffeine

onnit Apha BRAIN memory & focus

A double-blind, placebo-controlled study with Alpha BRAIN® by Onnit established its efficacy for memory enhancement. As a result of the 6-week supplementation, study participants showed higher scores in recall and verbal memory.

The manufacturers of Alpha BRAIN® combined 3 blends aiming for peak brain performance — fuel, flow, and focus.

Alpha Brain blends vitamins B6, B9, and B12, which are known for brain health. The brand included citicoline in its formula to beef up nerve protection and neurotransmitter activation.

These nootropic supplements are third-party tested for purity and quality. Also, their effects on mental performance have been studied, and the results were published in a peer-reviewed journal.

Active ingredients

Onnit Alpha Brain® includes 11 brain ingredients among B vitamins. We looked at some of the significant ones below.

Bacopa monnieri: This natural nootropic was shown to have the potential to address cognitive functioning by enhancing learning ability, attention, and ability to switch between tasks. Yet, a randomized control trial suggests that the use of bacopa monnieri may be associated with gastrointestinal side effects.

Phosphatidylserine (PS): This naturally occurring chemical in the human brain stimulates dopamine and serotonin production. Studies show that PS can be safely administered to address nerve deterioration and memory impairment while aging. PS combined with citicoline in Mind Lab Pro may have effects in reducing ADHD symptoms.

Mind Lab Pro bottle contains 60 capsules for 30 servings and is sold at $79.95 ($1.77 per serving).

4. Performance Lab — best ADHD nootropic with minimal ingredients


Performance Lab introduces Mind nootropic contains 4 patented ingredients known to improve memory, focus, and mental clarity. The combination of precursors for brain chemicals, this nootropic supplement is more likely to help achieve effects managing ADHD symptoms.

Sharp-PS® Green is a patented and soy-free version of phosphatidylserine in Performance Lab Mind. Limited scientific evidence suggests that PS may be a therapeutic approach to ADHD symptoms by reducing inattention.

Cognizin® citicoline is another precursor to a brain chemical involved in learning and memory. The combined administration of these two compounds demonstrated improved reaction times and performance.

The brand’s daily serving recommendation is 1 capsule which is a convenient serving size for busy people. If it’s suitable for you, try to stick with Performance Lab's recommended dosage guidelines in order to obtain the proposed benefits.

The supplements are made in the USA and UK in FDA-approved and cGMP-certified facilities.

Active ingredients

Out of 20 ingredients, let’s take a look at the most significant ones in Performance Lab.

Citicoline: Occurring naturally in the brain, this chemical is responsible for better memory and performance. Additionally, research reports that citicoline may reduce ADHD symptoms.

L-tyrosine: Studies show that it may be beneficial in cognitively demanding tasks or performance under stress.

Maritime pine bark extract: Although there is limited evidence regarding the effects of this ingredient in Performance Lab Mind, it is believed to demonstrate some antioxidant effects for brain cells.

A bottle of Performance Lab Mind contains for 30 servings and costs $59.00 ($1.96 per serving).

5. Vyvamind — best nootropic for ADHD and enhanced performance


Vyvamind presents the best neurostimulants to enhance performance with its formula containing caffeine, L-theanine, and L-tyrosine.

While caffeine is known for its immediate energy-boosting effects, make sure to follow the provider’s recommendations of taking 1 capsule early in the morning to avoid caffeine-related sleep problems.

Moreover, L-theanine taken together with caffeine has been reported in several studies to produce enhancing effects on cognition.

Research suggests that L-tyrosine may contribute to cognitive and physical performance in demanding situations. L-tyrosine in Vyvamind may increase dopamine, which in turn, leads to better cognitive performance and improved motivation.

Thanks to this formula and its benefits, Vyvamind may be a suitable ADHD nootropic for university students, emergency staff, office, and manual workers.

According to the provider, Vyvamind nootropic is made in the USA and meets cGMP-approved manufacturing requirements.

A bottle for a one-month supply contains 60 capsules. The daily recommended dose is 1 capsule, yet, for higher doses, you should consult your healthcare provider.

Active ingredients

Vyvamind contains 6 active ingredients. Each of them is wisely dosed and has several benefits for the user.

Vitamin B6 and B12: This vitamin complex in Vyvamind’s formula helps support brain health and prevent the loss of gray matter associated with neurodegeneration. While deficiency of these vitamins has been linked to premature brain aging, supplementation is one of the preventative approaches.

L-tyrosine: Researchers suggest that L-tyrosine supplementation is related to better cognitive and physical performance, particularly in stressful or cognitively demanding situations. This is likely to result from an increase in dopamine and adrenaline levels.

Caffeine and L-theanine: Supplementation with these two nootropic ingredients has been shown to increase alertness and attention in tasks.

One Vyvamind bottle costs $74.99 ($1.24 per serving).

Top 5 nootropic supplements for ADHD compared

BrandReviewPricePrice per servingServing sizeCapsules in the bottleIngredients for ADHDVitamins for brain healthCaffeineVegan/vegetarianOur pick for
NooCubeNooCube review$64.99$2.16260Alpha-GPCB1, B7, B12NoNoBest ADHD nootropic for visual memory
Mind Vitality-$69.99$2.33390PS, CholineB9, B6, B7, B12NoYesBest nootropic to support focus in ADHD
OnnitOnnit Alpha Brain review $79.95$1.77290Alpha-GPC, PSB6NoYesBest nootropic for ADHD without caffeine
Performance LabPerformance Lab review$59.00 $1.96130Citicoline, PS, L-tyrosine-NoYesBest ADHD nootropic with minimal ingredients
VyvamindVyvamind review$74.99$1.241–260CiticolineB6, B12YesYesBest nootropic for ADHD and enhanced performance

Do nootropics really work for ADHD treatment?

No. While nootropics may help to relieve ADHD symptoms by increasing concentration, focus, or memory, they cannot treat it. ADHD is a complex cognitive concern that requires a meticulous approach by a health professional.

Doctors may prescribe medications for regular use and to treat ADHD. In addition, ADHD comes in different types, and each of these types may be a subject of a specific treatment.

People with ADHD may often be reluctant to ingest prescription drugs such as Adderall due to a high risk of side effects and its addictive nature. In this case, nootropics may emerge as adderall alternatives to address ADHD symptoms.

The consumption of nootropics or replacing medications with them should be discussed with a healthcare professional.

What are the natural nootropic ingredients suitable for ADHD?

Besides synthetically produced ingredients replicating naturally occurring chemicals in the human brain, there are also natural herbs, extracts, and vitamins that may be suitable for people with ADHD.

You may obtain them from nutrient-dense foods. Yet, the amounts may not be sufficient to alleviate ADHD symptoms. Thus, you can take them as food supplements, vitamins, or nootropic formulations. Below, we discuss some of the most prominent natural ingredients for ADHD.

Omega-3 fatty acid

Studies show that people with ADHD have a deficiency in omega-3. These essential nutrients are involved in signaling and neural development. This process is related to the release of neurotransmitters, as well as the prevention of neurodegeneration and inflammation.

According to research, children with ADHD who were regularly supplemented with omega-3 had modest effects on ADHD symptoms and moderate alterations in symptoms. Fish, nuts, and seeds are good sources of this fatty acid.


L-theanine is an amino acid found in green tea leaves. This natural ingredient is extensively used in nootropics and often combined with caffeine.

L-theanine is a source of caffeine and catechins, which may beneficially influence ADHD symptoms. Catechins, for instance, have been shown in human and animal studies to play the role of neuroprotectors hindering the development of cognitive disorders.

This natural amino acid may improve working memory and reaction times. On one hand, l-theanine may relieve stress and anxiety. On the other hand, when combined with caffeine, L-theanine may increase alertness and accuracy in switching tasks.


Two of the well-known carotenoids are lutein and zeaxanthin, which have been shown to be beneficial for eye and brain health. These are naturally occurring compounds found in oranges, carrots, and pumpkins.

Carotenoids are involved in anti-inflammatory activities in the brain by reducing the excessive amount of reactive oxygen species (ROS). Another way these compounds work is by promoting brain-derived neurotrophic factor (BDNF), which is involved in nerve cells' survival, growth, and plasticity.

People with ADHD often face difficulties with memory and learning. Yet, the increased levels of BDNF were shown to enhance performance, studying, and memory in adults.

Bacopa monnieri

Supplementation with this ayurvedic herb is related to improved reaction times, attention, and ability to switch between tasks.

There is limited evidence referring to the influence of bacopa monnieri on depression, anxiety, and stress relief. More longitudinal studies are needed to establish its safety and potency for ADHD.

Other cognitive enhancers for ADHD

Besides natural herbs and extracts, nootropics, as well as vitamins, doctors may prescribe other cognitive enhancers for ADHD to regulate brain activity and behavior. These are synthetic compounds that have neuroprotective and nootropic properties.

Often, these are off-label treatments for ADHD called eugeroics and should be taken under a doctor’s supervision.

Below are 3 alternative or off-label cognitive enhancers for people with ADHD.


Piracetam was initially used to treat myoclonus — a condition characterized by a joint or a group of muscles jolting uncontrollably. Introduced in 1970, it became the first drug to be referred to as a nootropic.

Piracetam is involved in neurotransmission. It’s a known “cerebroactive” drug that is believed to activate the central nervous system and improve brain metabolism.

Although the available studies come with limitations, the above-discussed properties of piracetam can be considered worthwhile for ADHD. Possible side effects are anxiety, depression, drowsiness, dry mouth, and sleep disorders.


Noopept was created using the piracetam structure. It is also referred to as a nootropic for its neuroprotective and cognitive-enhancing abilities. This nootropic drug was designed to treat inflammation and anxiety.

In addition, this alternative formulation for ADHD symptoms is related to memory consolidation and learning. The underlying mechanisms of its activity may be associated with increased BDNF and neurotransmission.

Noopept may be a reliable cognitive enhancer for people with ADHD, though caution should be taken when supplementing to avoid side effects such as sleep disturbance, irritability, headaches, or dizziness.


Modafinil is a prescription drug used to treat sleep apnea, narcolepsy, and circadian rhythm disorders. Yet, there is evidence of its cognitive enhancing qualities among people with ADHD.

One of the treatment approaches to ADHD is to target dopamine activation in the brain. The regular consumption of modafinil is related to increased dopamine in the brain — increasing the feeling of reward and the ability to concentrate on one task for extended periods.

A doctor’s surveillance is crucial while using this stimulant compound to avoid adverse effects. Also, in rare cases, it can be misused among people prone to addiction.

How we compiled our list of best nootropics for ADHD in 2024

We did the research for you to make the selection a smooth process. When compiling our list of the best nootropics for ADHD, we looked for several critical aspects to establish product quality.

When buying nootropics to address ADHD symptoms, you should look out for products meeting the following criteria:

  • Ingredients
  • Brand reputation
  • Dosage
  • Price


Buy nootropics containing ingredients with established effectiveness to alleviate ADHD symptoms. While natural herbs or extracts may be beneficial for increased mood or energy, they may not be strong enough to help you regulate the complex mechanism of brain activity.

Also, look for supplements that include phosphatidylserine and citicoline, or at least one of these chemicals. Although these are lab-created alternatives to natural chemicals, their supplementation is believed to be safe and beneficial for ADHD.

Brand reputation

Brand reputation is generated with time and due to the company's transparency with its customers. The fact that the brand has been in the market for a long time may tell us about their products that actually work for ADHD symptoms.

Also, checking users’ feedback on the brand’s official review platforms is a good idea. While on the official website, you can often find sufficient reviews, they may read too good to be true.


Opt for the best brain supplements that come in effective and safe doses. Often nootropics are a blend of up to 20 ingredients. While this feature may seem like an ideal approach to cognitive boost, what matters most is the doses of each ingredient.

Proprietary blends of nootropic compounds do not allow learning the exact amount of each component. And sometimes, the quantities included may not be sufficient to address concentration, focus, and memory improvements.


When buying ADHD nootropics, pay attention to the capsule content in the bottle. Then, learn about the recommended daily doses and servings per container.

With this information in mind, you can calculate your daily spending and have an image of how affordable the product is.

You can refer to our comparison table above for the pre-calculated prices per serving for each product on our list.

Are nootropics safe for child ADHD?

No. Despite numerous brands affirming the safety of nootropics for children’s use, the content in their supplements may not be suitable for children.

Most of the nootropic formulations have caffeine or caffeine anhydrous — harsh stimulants triggering quickened heart rate or caffeine intoxication.

Children with ADHD may have common deficiencies such as:

  • Iron
  • Zinc
  • Fatty acids
  • Vitamins

Supplementation with these essential minerals and vitamins is one of the methods to support ADHD symptoms in a child. Moreover, some natural extracts believed to be healthful to a child with ADHD are the following:

  • Rhodiola rosea
  • Ginkgo biloba
  • Panax ginseng

Although these are natural and effective compounds, doctor’s supervision is crucial when administering them as a complementary treatment for ADHD in children.

Can nootropics replace prescription medication?

No. Prescription drugs are FDA-approved to treat ADHD and are formulated following rigorous testing and studies. On the contrary, we still need firm evidence to establish the safety and efficacy of nootropics.

People aiming to avoid the long-term side effects of prescription drugs may turn to nootropics as alternatives. Although they may induce better cognitive performance, you should learn about these agents' proper usage and dosage.

If you plan to use nootropics as a complementary treatment for ADHD, you should first talk to your doctor. Remember that a healthy diet and lifestyle could increase the viability of ADHD treatments.

Other benefits of nootropics for ADHD

Best Adderall alternatives are over-the-counter and possibly safer means to reduce ADHD symptoms.

Best supplements for focus and concentration are therapeutic approaches for enhanced brain performance.

Best nootropic drinks let you experience the benefits of nootropics with ease.

Best nootropics for anxiety may help strengthen body's resistance to stress.

Best nootropics to optimize brain health are effective means for peak mental performance.

Best nootropics for studying can help increase your attention and reaction time during exams.


Vitamin B7: Vitamin B7 was shown in animal studies to be helpful in the prevention of neuropathic pain by reducing inflammation. Also, it’s involved in pathways promoting neuron survival and plasticity.

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Fiona Helen Hutchinson
prefix 8 months ago
Looked up noocube on trustpilot, there is not one not even one good review. Which leads me to ask why you have suggested it.
Mariam Hakhyan
prefix 5 months ago
Hello, Fiona, and thank you for your interest in Healthnews.

The effects and experience with the supplement or brand can be individual for everyone. When selecting the best nootropics on the market, we considered the ones with science-backed formulations, Certificate of Analysis, and manufacturing. Moreover, if you are planning to incorporate any new supplements into your diet, consult your healthcare provider first.