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Best Anxiety Supplements in 2024: Calming Supplements to Manage Stress

Anxiety is a distressing emotional state characterized by tension, worrisome thoughts, and physiological changes such as elevated blood pressure. It can significantly disrupt daily activities, including job performance, academic performance, and interpersonal relationships.

According to a 2017 Harvard study, it is estimated that at least 31.1% of adults in the United States have experienced symptoms of anxiety at some point in their lives, and this percentage continues to rise over time.

To navigate particularly stressful and tense periods, it's essential to ensure that your diet supports your body's resilience. Therefore, we have compiled our top supplements for anxiety and stress to help you enhance your nutrition and enjoy a greater sense of calm.

Best supplements for anxiety: shortlist

  1. NuLeaf Naturals — best product for anxiety with great flavor
  2. A Quality Life — best supplement for anxiety to aid with sleep
  3. Joy Organics — best product to boost overall wellbeing
  4. Bulletproof — best supplement to enhance brain health
  5. Purovitalis — best supplement with vitamin D for anxiety

How we chose the top supplements for anxiety and stress in 2024

We've assembled a list of key criteria to consider when choosing the best supplements for anxiety. This comprehensive set of guidelines caters to various individuals searching for the perfect match to suit their needs.

PriceThird-party testingIngredientsManufacturing standards
$16.99–49.00Ingredient amounts align with the label and are free from harmful substancesHigh-quality and safe ingredientsDisclosure of manufacturing practices and certifications from reputable third-parties
  • Price. The price of a supplement should match its quality and key features. We evaluated what each product offers and evaluated the price range of each brand.
  • Third-party testing. We selected top supplements for anxiety that have undergone thorough assessments by independent laboratories. This ensures that the ingredients and quantities align with what is stated on the label and are free from any harmful substances.
  • Ingredients. High quality and safe ingredients are essential in selecting a good supplement. We assessed each brand's commitment to using scientifically supported ingredients and adhering to rigorous production standards.
  • Manufacturing standards. We evaluated brands based on their adherence to manufacturing practices, including certification by cGMP and other reputable parties. In addition, we considered their efforts towards sustainability in their production processes.

Best anxiety supplements: an overview

In this overview of our best anxiety supplements, we have selected brands offering a diverse range of ingredients including magnesium, vitamin D, and ashwagandha.

Supplements are commonly associated with addressing nutritional deficiencies. However, certain ingredients are recommended not only for improving dietary intake but also for potentially mitigating mild anxiety and stress symptoms. The synergy between a balanced diet and these potential anxiety-relief properties may be key in supporting the body and mind during busy or stressful periods.

1. NuLeaf Naturals — best natural product for anxiety with tasty flavor

NuLeaf CBD Gummies

NuLeaf Naturals CBD full-spectrum gummies is a great natural product for anxiety and stress enriched with full-spectrum CBD and organic ingredients to create a potent formula that promotes rewind of body and mind. These gummies are sourced from farms in the USA and undergo advanced subcritical and supercritical CO2 extraction, resulting in a formula that is free from harsh chemicals and highly concentrated.

CBD, a compound derived from cannabis, is suggested to interact with the Endocannabinoid System, which plays a role in various physiological processes, including anxiety, and stress management. The potential consumption of cannabidiol has been associated with stress relief and a soothing sensation, among other effects.

The recommended intake, 30 mg per day, can be easily measured in two gummies which individuals can enjoy at their preferred time of the day.

It is available for $49.00 and includes 900 mg of CBD per bottle.

2. A Quality Life — best supplement for anxiety and sleep problems

A Quality Life organic ashwagandha

Quality of Life's Organic Ashwagandha is a meticulously crafted formula designed for stress relief, harnessing the benefits of both ashwagandha root and black pepper. This formula is USA-sourced and third-party tested, guaranteeing the absence of harmful chemicals in its formulation.

Ashwagandha is an ingredient renowned for its potential to alleviate anxiety. Its suggested efficacy in both pre-clinical and clinical studies points to its ability to reduce stress, while also enhancing sleep quality. Additionally, it may offer benefits in terms of focus, memory, and mood regulation, as well as fortifying the body's resilience against pathogens and diseases.

Each product contains 30 servings per package, with the brand recommending a daily intake of 2 pills. Individuals are advised to take the two capsules 20–30 minutes before a meal or as directed by a healthcare provider.

This product is priced at $32.95 and contains 1300 mg of ashwagandha per serving. The brand offers free shipping on all orders.

3. Joy Organics — best product to boost well-being

Joy Organics CBD oil Tranquil Mint

Joy Organics Tranquil Mint CBD formula, with broad-spectrum cannabidiol and selected oils, is designed to provide a calming and soothing solution for individuals dealing with stress. Sourced from hemp grown in the USA and holding USDA certifications, this tincture undergoes rigorous testing for purity, potency, and safety, including third-party lab testing at an ISO-accredited facility.

The vegan-friendly formulation includes organic extra-virgin olive oil as a carrier, along with organic peppermint essential oil, providing a light and refreshing mint flavor. It offers four strengths, ranging from beginner-friendly (15 mg per serving) to a high-potency (75 mg per serving).

Joy Organics recommends consuming one dropper of their tincture daily. They also state that effects may become noticeable within 15–30 minutes after consumption. However, we would like to remind you to be cautious when determining your CBD dosage and recommend consulting a healthcare provider to ensure it aligns with your specific requirements.

It is available for $35.96 and includes a 90-day return policy.

4. Bulletproof — best anxiety supplement to boost brain health

Bulletproof Magnesium

Magnesium supplement, crafted from pure, science-backed ingredients, is designed to promote relaxation and well-being. Its formulation, free from soy, dyes, and gluten, offers a robust boost to overall well-being.

Bulletproof contains magnesium citrate, associated with potential benefits for alleviating mild to moderate levels of anxiety. Additionally, magnesium may contribute to inhibiting the physiological stress response system.

This vegan supplement boasts 320 mg of magnesium per serving. Users are advised to take 3 pills daily at their preferred time, along with the beverage of their choice. However, the brand does not recommend exceeding a daily intake of 350 mg of magnesium.

It is available for $16.99 and includes 90 capsules per package.

5. Purovitalis — best supplement for anxiety with vitamin D


Liposomal Vitamin is an innovative liposomal formula crafted with vitamin D, designed to alleviate stress and support the immune system.

Low levels of vitamin D have been linked to increased symptoms of depression and anxiety. Therefore, in the case of deficiencies, supplementing with this vitamin may help alleviate anxiety symptoms.

The brand subjects the supplements to rigorous third-party testing to ensure their freedom from any harmful chemicals. Additionally, it holds GMP certification, maintaining high-quality standards for all its products.

Each serving contains 50 mcg of vitamin D enclosed in a liposomal capsule, which according to the brand, enhances the product’s bioavailability.

The brand recommends taking a capsule per day, preferably in the morning with breakfast.

It is available for $20 and includes 60 servings per package.

Comparing the best supplements for anxiety

ProductPriceCOA available onlineDaily servingTotal amount per servingIngredients for stress and anxiety relief
NuLeaf Naturals$49.00Yes2 gummies30 mg of CBDFull-spectrum CBD
A Quality Life$32.95Yes2 pills 1300 mg of ashwagandhaAshwagandha
Joy Organics$35.96*Yes1 dropper30 mg of CBDBroad-spectrum CBD
$16.99N/A 3 pills320 mg of magnesiumMagnesium
Purovitalis $201 pill 1 scoop50 mcg of vitamin DVitamin D

* — prices vary depending on the product size.

Supplements for anxiety and stress: do they really work?

An individual's susceptibility to stress can be influenced by a variety of factors. One of those factors can be dietary intake, which in turn may affect our mood and well-being.

Certain mental health issues have been associated with elevated levels of "dietary inflammation," characterized by increased consumption of inflammatory foods (such as trans fats and refined carbohydrates) and decreased intake of nutrient-rich foods believed to possess anti-inflammatory properties (such as omega-3 fats).

Supplements and vitamins for anxiety can play a crucial role in balancing one's diet and addressing potential nutritional deficiencies. This is essential for enhancing overall well-being and also preparing the body to better cope with periods of heightened stress.

However, it's important to note that supplements cannot prevent or treat anxiety disorders or their symptoms. Prolonged feelings of distress may signal underlying hormonal, neurotransmitter, or anatomical disruptions, Therefore, individuals should consult with their healthcare provider to determine the most suitable treatment for their needs.

Natural supplements for anxiety: can they help?

Natural supplements for anxiety and stress include a wide range of ingredients like ashwagandha, magnesium, and vitamin D.

Ashwagandha, commonly found in supplements, exhibits the potential to enhance cognitive function and manage stress. Rooted in Indian medicine, it is associated with a generally safe profile and may aid with stress and sleep disturbances, and may enhance memory, executive function, and attention.

Magnesium, a micronutrient in supplements, crucially influences brain function and mood. Research has found that magnesium may help with brain functions that reduce anxiety, fostering relaxation and tranquility.

Lastly, vitamin D has immunomodulatory, neuroprotective, and neurotrophic properties and may affect the brain tissues involved in the pathophysiology of anxiety. Low vitamin has been associated with increased symptoms of this condition.

Natural supplements vs. synthetic supplements: a comparison

Dietary supplements are available in various forms, including tablets, capsules, gummies, powders, drinks, and energy bars. Natural supplements are crafted from botanical ingredients or their extracts, while synthetic ones are produced in labs with chemical compounds.

The primary distinction between natural and synthetic supplements lies in the isolation of compounds in the former. In any case, we remind you that both supplement types should be consumed with caution and the supervision of a healthcare provider.

The concept of vitamin and mineral bioavailability in dietary supplements lacks standard scientific and regulatory definitions. Many supplements contain excessive doses of vitamins and minerals, which may not be accurately reflected on the label and are unnecessary for many individuals.

Whether choosing synthetic or natural supplements, it is always important to check their label to ensure the safety of the product. Also, it's essential to remember that supplements cannot replace the diverse array of foods vital for a healthy diet.

Choosing the best supplements for anxiety — conclusion

Natural supplements may be a good way to mitigate the risk of specific vitamin and mineral deficiencies, which can adversely affect overall well-being. Furthermore, certain products may contribute to fostering feelings of calmness and tranquility, potentially alleviating stress in both the body and mind.

Nutrition plays an important role in preparing the body to cope with stressful periods. A well-balanced diet combined with regular exercise may aid in managing stress and anxiety, ultimately enhancing quality of life. However, supplements should never be used as a treatment for anxiety disorders. A consultation with a physician is essential to get the right treatment, which may include cognitive and pharmaceutical interventions.

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