Brain supplements are also known as cognitive enhancers or nootropics. The best supplements for focus and concentration are known to play a role in enhancing brain activity, cognitive function and mental sharpness.
People with ADHD and chronic events of brain fog and older adults may need supplemental boosts for better cognitive function. Yet, not all the supplements work similarly, and some of them may even result in unfavorable outcomes.
Hence, we gathered the top-rated brain supplements to help focus and to stimulate concentration.
Best supplements for focus and concentration: shortlist
- Elysium — best brain supplements for older adults
- Vyvamind — best for optimal energy and concentration
- Mind Lab Pro — best brain supplement for information processing
- NooCube — best pills for focus and vision health
- Nooceptin — best caffeine-free brain and energy booster
- Hunter Focus — best brain supplements for sustained attention
How to choose the best supplements for focus and concentration?
When choosing the best supplements for focus and concentration, we used several criteria to evaluate supplements’ quality, safety, and efficacy for brain enhancement.
Ingredients | Clean and proven ingredients |
Quality | Third-party testing |
Manufacturing | cGMP-compliant facilities |
Price per serving | $1.00–$2.30 |
- Ingredients. Most supplements to help focus have several active ingredients, but when buying them, look for scientific evidence proving their efficacy.
- Quality. The quality of the supplements is established through third-party testing. This is an assurance from independent labs that the product doesn’t contain contaminants and is safe for daily consumption.
- Manufacturing. Dietary supplements are not FDA-controlled. Providers should manufacture them in FDA-approved sites following Good Manufacturing Practices (GMP) to ensure their safety and purity.
- Price-dosage ratio. Choose the best brain supplements that offer science-backed health benefits in optimal doses and prices.
Best supplements for focus and concentration in 2023: overview
In this overview of the best brain supplements in 2023, we gathered brands providing nootropic formulations, vitamin complexes, and CBD products.
Nootropics are also called “smart drugs” because of their therapeutic abilities for improved memory, focus, and cognitive performance. People who find it hard to get motivated and stay focused on one task for longer or those who have low energy can benefit from these “smart drugs.”
Most of the products on our list have more than 10 active ingredients, each of which has specific effects on mental well-being and brain activity. We will discuss the best supplements on our list and explain the role each active ingredient plays in cognitive enhancement and brain health.
1. Elysium — best brain supplement for older adults

Elysium presents Matter, which is a vitamin complex designed to prevent brain aging.
Elysium uses a tri-vitamin complex in its Matter supplements — vitamins B6, B12, and folate.
Increased homocysteine is associated with the loss of gray matter volume in several brain regions important for cognitive functions, including memory and emotions. Based on scientific findings, these vitamins play a role in balancing homocysteine levels in the brain, potentially reducing the risk of cognitive disorders.
Elysium’s Matter was created in partnership with Oxford University. The tri-vitamin formula and its effects on brain deterioration were evaluated in the study conducted with older adults.
The study's results suggest that Matter supplements reduce aging-induced cognitive decline. However, results may vary from person to person.
Besides the vitamin complex, Matter contains omega-3 lysine and EPA+DHA, which may benefit brain structure and function. It was shown that lower omega-3 levels are associated with ADHD. So, supplementation may be beneficial for people who may require focus and attention support.
One bottle of Elysium Matter contains 60 tablets for 30-day use and costs $60.00 ($2.00 per serving).
2. Vyvamind — best for optimal energy and concentration

Vyvamind may be the best option for an instant energy boost as it contains caffeine anhydrous, which is a stronger stimulant than ordinary caffeine.
In addition, the presence of vitamin B6 and B12 in combination with amino acids L-theanine and L-tyrosine may play a role in enhancing concentration.
As Vyvamind providers claim, L-theanine may soothe the effects of caffeine by preventing jitters. The combination of L-theanine and caffeine was shown in a study to improve alertness and attention accuracy when switching tasks.
Citicoline in Vyvamind’s formula was observed to play a role in relieving ADHD symptoms, as well as improving memory.
Another study with caffeine and citicoline demonstrated that this combination might improve concentration and reaction times in adults.
Vyvamind supplements support boosting brain activity with their products manufactured in FDA-approved sites.
The serving size is 1 capsule daily. If you plan to increase the intake, consult your doctor first.
A bottle of Vyvamind costs $74.99 ($1.24 per serving).
3. Mind Lab Pro — best brain supplement for memory

Clinical trials with Mind Lab Pro have shown it to be effective for information processing, indicating significant improvements in focus, attention, and decision-making. These effects were observed after 30-day supplementation.
In addition to brain vitamins, Mind Lab Pro contains natural adaptogens and neurotransmitter activators. Study scientists assume the above-discussed benefits might result from bacopa monnieri, citicoline, lion’s mane, maritime bark extract, L-tyrosine, and phosphatidylserine.
According to the researchers, people working under pressure and the elderly may benefit from these brain supplements.
Another research study suggests that Mind Lab Pro positively affects memory, including immediate and delayed recall.
Mind Lab Pro nootropic is formulated in cGMP-compliant facilities and has been third-party tested for safety and quality. It does not contain caffeine, thus, may not pose sleep issues.
These brain pills are certified vegan and Clean Label Project for not containing allergens and additives.
One bottle of Mind Lab Pro containing 30 servings costs $69.00 ($2.30 per serving).
4. NooCube — best pills for brain and vision health

NooCube contains Lutemax® 2020, an ingredient demonstrated to positively affect vision and cognitive function. Lutemax® 2020 combines two well-known carotenoids — lutein and zeaxanthin isomers.
Findings suggest that supplementation with these compounds may play a significant role in elevating levels of brain-derived neurotrophic factor — essential for neuronal growth and survival, which is a key to learning and memory.
People experiencing eye strain may often be fatigued and have a slow mental function. Hence, they may benefit from this formula of NooCube.
Among 13 ingredients, NooCube contains bacopa monnieri, which may participate in cognitive enhancement and improve reaction time.
The providers combine resveratrol and pterostilbene — well-known antioxidants having neuroprotective properties. They may support memory and healthy brain aging by reducing inflammation.
NooCube offers caffeine-free energy and focus supplements to support increased concentration, as well as eye and brain health.
One bottle of NooCube brain supplements is sold for $64.99 ($2.16 per serving).
5. Nooceptin — best caffeine-free brain and energy booster

Unlike its sister nootropic supplement Vyvamind, Nooceptin contains no caffeine — suitable for people sensitive to stimulants.
People who are looking for a short-term brain and energy boost without caffeine can benefit from the L-theanine content in these brain pills. Plus, a limited number of studies show that rhodiola rosea can help you address fatigue and play a role in mental performance.
Nooceptin offers pills that help you focus by including an optimal dose of citicoline. A study conducted with 60 adult women demonstrated citicoline effects on attention, focus, as well as the ability to control impulsiveness.
One of the studies cited on the website suggests that panax ginseng, one of the ingredients in the capsule, may play a role in improving brain function in people with moderate cognitive impairment.
In a clinical trial, supplementation with either ginkgo biloba, ginseng, or a combination of both, was associated with improved cognitive functioning. Healthy young participants were found to perform better on memory and attention tasks after supplementation with these extracts.
The supplement providers claim their products are manufactured in FDA-approved sites.
One month-supply of Nooceptin costs $69.00 ($2.30 per serving).
6. Hunter Focus — best brain supplement for sustained attention

Hunter Focus is the best supplement for sustained attention by combining phosphatidylserine (PS) with ginkgo biloba. A study of participants taking PS and ginkgo biloba together showed better reaction times in attention tasks.
Hunter Focus can be a suitable supplement for targeting ADHD symptoms, thanks to the abovementioned combination. Yet, it shouldn’t be used as an alternative to prescription medication without consulting your doctor.
The herbal ingredients are included in a capsule with 6 other vitamins that help with focus and concentration — vitamins B6, B12, B9 (folate), D3, K2, and C.
Recent studies concluded that balanced vitamin C levels in the blood are related to brain vitality, including better mood, sustained attention, and motivation in young adults.
According to the website, Hunter Focus’s attention and memory booster supplements are manufactured in FDA-approved and cGMP-registered facilities in the U.S. and UK.
One bottle of Hunter Focus contains 180 capsules for 30 servings. The suggested daily intake is 6 capsules. The starter bottle for a 1-month supply is sold for $90.00 ($3.00 per serving).
Comparison of top 5 brain supplements
Brand | Price | Serving size | Price per serving | Capsules in the bottle | Formula | Number of ingredients | Caffeine | Vegan/vegetarian |
Elysium | $60.00 | 2 tablets | $2.00 | 60 | Vitamin complex | 6 | No | Yes |
Vyvamind | $74.99 | 1 capsule | $1.24 | 60 | Neurostimulant | 6 | Yes | Yes |
Mind Lab Pro | $69.00 | 2 capsules | $2.30 | 60 | Nootropic | 11 | No | Yes |
NooCube | $64.99 | 2 capsules | $2.16 | 60 | Nootropic | 13 | No | No |
Nooceptin | $69.00 | 2 capsules | $2.30 | 60 | Nootropic | 7 | No | Yes |
Hunter Focus | $90.00 | 6 capsules | $3.00 | 180 | Nootropic | 20 | Yes | Yes |
How we compiled our list of best supplements for focus and concentration in 2023
When composing our list of best pills that help you focus, we considered safety and efficacy criteria of the products.
Some of the essential criteria we considered were:
- Ingredients
- Testing
- Dosage
- Manufacturing
Ingredients
Most of the brands offering memory and concentration booster supplements combine more than 10 ingredients. However, more ingredients are not a guarantee of higher efficacy. Moreover, their interaction is understudied.
We tried to include nootropics into our list that have science-backed ingredients and are unlikely to pose significant health concerns to the user.
Testing
Third-party testing is critical for dietary supplements as they are not FDA-regulated. Independent labs should test the purity and quality of these pills to establish their safety.
Also, this type of testing can reveal the presence of ingredients not mentioned on the product label and display the exact amount of ingredients in the capsule. Also, it’s an excellent practice to detect any harmful compounds in the supplements.
Dosage
Choosing the right dosage for your health requirements is important to avoid side effects. Always look for supplements offering optimal doses proven by research.
If in doubt, consult your doctor for dosage recommendations specific to you.
Manufacturing
Good manufacturing practice or short GMP is an essential aspect of supplement production. This type of manufacturing can ensure you are getting quality capsules without contaminants.
FDA requires following the rules of a hygienic environment in manufacturing sites and utilizing quality equipment.
Are brain-boosting supplements safe to take?
Brain supplements are generally safe to take for almost everyone. To stay safe when using supplements for focus and concentration, you should also follow the usage recommendation on the product label.
Also, nootropics are not FDA-approved and do not require a prescription. Thus, their safety depends on the production process and ingredients.
Some companies may also choose to utilize extensive third-party testing to ensure their products come without any harmful additives, allergens, or harsh stimulants.
Ideally, before deciding on taking any supplements, you should consult your healthcare provider for better dosage, frequency, and usage length recommendations.
Often you can read a long list of ingredients on the product label. However, some of these ingredients may interact with each other’s effectiveness or with the supplements and prescription drugs you are already using.
Can brain pills replace prescription medications?
Brain pills cannot replace prescription memory medications. If the memory and attention concerns are mild, you can take brain supplements to help you focus and concentrate on daily tasks.
In cases of ADHD accompanied by memory and focus issues, people may be prescribed Adderall or similar drug formulations. Yet, most of the users may experience side effects or addiction to it.
In some cases, using Adderall alternatives in the form of nootropics or brain supplements can come in handy since the natural formula in these supplements are easy to withdraw from and does not cause long-term side effects. However, the consumption of brain supplements or the replacement of current medications should be agreed upon by a healthcare provider.
Why you should take brain supplements
You should consider taking brain supplements if you aim to boost your cognitive abilities.
If you are required to multitask and stay alert under demanding situations, you may benefit from using brain pills. Their active ingredients serve different functions in the brain. Some may act as precursors for dopamine and norepinephrine neurotransmitters, which play a role in decreasing stress and enhancing working memory.
Benefits related to the use of brain supplements are the following:
- Improved focus, concentration, and memory
- Decreased mood swings
- Slowed down cognitive decline
- Improved learning
Improved focus, concentration, and memory
Nootropics aid in optimizing brain health by improving blood flow to the brain — resulting in better focus and concentration. Plus, certain well-studied ingredients in brain supplements may be involved in activating the neurotransmitter norepinephrine.
It was observed that people with ADHD have lower norepinephrine levels which interfere with concentration and focus. Moreover, according to studies, this neurotransmitter may participate in memory consolidation during sleep.
Decreased mood swings
Nootropics are believed to reduce stress and anxiety by working on the activation of neurotransmitters, such as GABA and serotonin, which have calming and mood-boosting effects.
Moreover, L-theanine and L-tyrosine may help to lower levels of stress and anxiety by increasing dopamine and norepinephrine.
Slowed down cognitive decline
Though scientists have controversial opinions about brain supplements’ effects on cognitive decline, some findings suggest that they may prevent premature cognitive decline and neurodegeneration.
Limited data support the idea that brain supplements may assist in nerve regeneration lowering the chances of age-related mental disorders such as Alzheimer’s and dementia.
Improved learning
The main neurotransmitter involved in learning is acetylcholine. The levels of this neurotransmitter are observed to be lower in people with ADHD — thus affecting learning and memory.
The best brain supplements containing omega-3 fatty acids, ginkgo biloba, and ginseng may regulate the acetylcholine level and boost learning and recalling abilities in people with and without ADHD.
Ingredients used in natural cognitive supplements
Most brain, memory, and focus-boosting pills contain up to 20 ingredients. Generally, these are natural extracts, herbs, amino acids, and vitamins.
The following nootropic compounds are the most frequently used in brain supplements:
- Ginkgo biloba
- Rhodiola rosea
- Citicoline
- L-theanine
- L-tyrosine
- Lion’s mane mushrooms
- Phosphatidylserine (PS)
Some brands go a different direction by designing brain pills with the vitamin B family, fatty acids, and antioxidants such as resveratrol.
It is essential to know that while these ingredients have been scientifically reviewed for their effectiveness and safety, their interaction is poorly understood. Thus, before taking any nootropic stacks, consult your healthcare provider.
Can vitamins help with focus?
Considering that vitamins may take part in supporting overall brain health, they may improve focus. For instance, vitamins B6, B9 (folate), B12, C, and D are believed to be the best vitamins for memory and alertness.
People deficient in these vitamins showed a weaker ability to focus on tasks for longer than people with adequate levels.
B6 and B12 are especially known as focus vitamins for their involvement in maintaining healthy neurons and better concentration. More to this, vitamin C benefits motivation and lengthens attention span during tasks requiring focused attention.
One of the significant vitamins for memory is B9 or folate. Studies show lower serum folate levels are associated with impaired memory and an increased risk of cognitive decline with age.
All in all, nootropics and brain vitamins for memory are gaining popularity for their positive effects on cognition. Some people may take them on their own or choose to combine them with prescription medications. In any case, the use of these OTC brain pills should be consulted with a doctor.
Share your experience with nootropic supplements or brain vitamins in the comments. Have you achieved the effects you were expecting? How do brain pills help you with cognitive activities?
Other benefits of nootropics for focus
Best nootropics to optimize brain health may help to prevent neurodegeneration.
Best nootropic drinks offer a convenient way to consume nootropics.
Best nootropics for ADHD are believed to support cognitive performance in demanding tasks.
Best nootropics for anxiety contain adaptogens delivering calming and anxiolytic effects.
Best Adderall alternatives are safer nootropics available over-the-counter.
Best nootropic pre-workout are great to improve your workout and stay alert.
Best nootropic stacks contain cognitively-enhancing ingredients to boost mental performance.
Best memory pills are nootropics helping recall and memory consolidation.
FAQ
Can supplements actually improve your focus?
Brain supplements may help improve focus. By increasing the blood flow to the brain and acting as precursors to neurotransmitters, these pills can boost concentration and even lengthen attention span. However, the effects may vary from person to person.
What vitamin deficiency causes a lack of focus?
Vitamin B6, B9, B12, D, and C deficiencies may be related to a lack of focus. Low levels of iron and omega-3 fatty acids may also cause poor focusing abilities.
How do I stay focused while studying?
Taking nootropics or so-called focus pills can be one of the ways to stay concentrated during studying. Other than that, you can practice breathing exercises or drink energy-boosting tea before studying.
What is the best memory supplement for older adults?
Concluding from our research, the best memory supplement for seniors can be Elysium Matter. This vitamin complex is scientifically proven to assist brain health and prevent cognitive decline in older adults.
- Nutrients. Vitamins and Minerals for Energy, Fatigue and Cognition: A Narrative Review of the Biochemical and Clinical Evidence.
- Pharmacology Biochemistry and Behavior. Behavioral and cognitive effects of tyrosine intake in healthy human adults.
- International Journal of Food Sciences and Nutrition. Improvements in Concentration, Working Memory, and Sustained Attention Following Consumption of a Natural Citicoline-Caffeine Beverage.
- Frontiers in Psychology. Neurotransmitters as food supplements: the effects of GABA on brain and behavior.
- Food and Nutrition Sciences. Improved Attentional Performance Following Citicoline Administration in Healthy Adult Women.
Show all references
- The Journal of Nutrition. Citicoline and Memory Function in Healthy Older Adults: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
- Frontiers in Behavioral Neuroscience. Working memory reloaded: tyrosine repletes updating in the N-back task.
- Journal of Medicinal Food. Effects of l-Theanine on Cognitive Function in Middle-Aged and Older Subjects: A Randomized Placebo-Controlled Study.
- Human Psychopharmacology. Acute cognitive effects of standardised Ginkgo biloba extract complexed with phosphatidylserine.
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