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Best Supplements for IBS in 2024: Top Recommendations

Supplements for irritable bowel syndrome (or IBS) may be one of the ways to manage the symptoms of this condition and support smoother function of your digestive system. If you are looking for additional strategies to address some of the IBS symptoms, it can be difficult to find the best supplements for IBS as there are a wide range of options on the market.

We crafted this article to help you choose the most suitable product for your case. Our article will feature 5 products that you may find helpful in addressing such issues as bloating, constipation, or upset stomach.

Best supplements for IBS: a shortlist

  1. Unbloat — best probiotic supplement for IBS symptoms
  2. Routine — best IBS supplement for women
  3. VSL#3 — best medical food for IBS management
  4. Ritual — best third-party tested probiotic supplement
  5. Oweli — best supplement with a 100-day satisfaction guarantee
  6. YourBiology — best probiotics for IBS featuring a wide range of strains
  7. Purovitalis — best vitamin D supplement for IBS symptoms

How we compiled our list of the best IBS supplements?

IngredientsProvider reputationCustomer experiencePrice
Contains ingredients that may address IBS symptomsEstablished brandPositive reviews, generous refund policies$0.34–2.67 per serving
  • Ingredients. We analyzed the product’s label to understand better how it may affect IBS symptoms and included products that may assist in their management.
  • Provider reputation. With so many products on the market, it is worth considering brand reputation. We included products that are manufactured by reliable brands.
  • Customer experience. We analyzed reviews and refund policies to gain a deeper understanding of the customer experience.
  • Price. As IBS supplements have different formulations, their prices may vary greatly. To help you compare the products, we calculated the price per serving.

Best supplements for IBS: overview

If you are looking for the best supplements for IBS diarrhea, constipation, bloating, or abdominal pain, we have prepared a list of options you can choose from. Below, we will briefly describe every product and why we think they are worth considering.

1. Unbloat — best probiotics supplement for IBS

Unbloat Daily Capsules

Unbloat is a probiotic supplement that may help to relieve some of the IBS symptoms. One serving of this product delivers 25 billion CFU of beneficial bacteria from 7 different strains. Research studies indicate that probiotics may reduce such symptoms as diarrhea, bloating, and abdominal pain in patients with IBS.

Additionally, this product contains a wide range of ingredients that may be beneficial for the digestive system such as folic acid, magnesium, digestive enzymes, and certain herbs. For instance, some evidence based on a rodent study suggests that supplementing with folic acid may relieve visceral pain in IBS patients.

As of now, Unbloat is priced at $65.95 without a subscription. As it contains 30 servings per jar, it would cost you $2.20 per day if you opt to purchase this supplement. Moreover, this product is covered by a 30-day refund policy.

2. Routine — best IBS supplement tailored for women

Routine Probiotics for Her

Tailored for women’s health, Routine is a probiotic supplement that may also help with IBS symptoms such as bloating, constipation, and flatulence. A single portion of this product provides 24 CFU of beneficial bacteria sourced from five distinct strains.

As stress can negatively influence IBS symptoms, this product stands out due to Ashwagandha, a well-known adaptogen that may help to promote a sense of calmness.

According to the manufacturer's assertion, Routine utilizes delayed-release capsules designed to transport beneficial bacteria to the intended destination.

If you choose to purchase Routine, right now one package containing 30 servings is priced at $39.95 (or $1.33 per serving). This product is also covered by a 30-day refund policy in case you do not find yourself completely satisfied with the results.

3. VSL#3 — best medical food for people with IBS

VSL probiotics

VSL#3 is a probiotic medical food product that delivers 112.5 billion CFU from 8 strains per capsule. It is more potent than most over-the-counter (OTC) probiotic supplements and, thus, should be used under the supervision of a physician. Specially formulated to manage microbial imbalance, VSL#3 may help to reduce IBS symptoms.

As a medical food, it is subject to higher standards. Furthermore, VSL#3 has been clinically tested and shown to be effective for the management of certain conditions, e.g., ulcerative colitis.

If you decide to purchase VSL#3, one bottle would cost you $65.95. As the dose of this product can be either 1 or 2 capsules (this should be determined by your doctor), one serving comes to either $1.10 or $2.20. The shipment of VSL#3 is controlled for temperature to safeguard the bacteria.

4. Ritual — best third-party tested probiotic supplement for IBS


If brand transparency and reliability are the main priority for you, Ritual is our top choice. Ritual places a strong emphasis on its dedication to openness and strict quality control, which includes independent testing and traceable ingredients.

Ritual delivers 11 billion CFU of live bacteria. It features two of the most well-studied beneficial bacterial genera: bifidobacterium and lactobacillus. These strains have been extensively studied across various health domains and may also help to reduce IBS symptoms.

If you opt to purchase Ritual, one bottle is currently priced at $54.00 (or $1.80 per serving). This product is also covered by a 30-day refund policy.

5. Oweli — best IBS supplement with a 100-day satisfaction guarantee


This Oweli probiotic supplement is a perfect choice for people who are exploring products that may help them tackle IBS symptoms. For every purchase, Oweli offers a 100-day satisfaction guarantee: if you are not happy with the results, you can ask for a refund.

When it comes to the supplement itself, Oweli boasts 40 billion CFUs of beneficial bacteria from 4 distinct strains. Moreover, the manufacturer of this supplement employed MAKtrek Bi-Pass Technology to protect probiotics from stomach acid so they would be able to reach small and large intestines more effectively.

Right now, you can get one bottle of Oweli for $44.99 without the subscription. One bottle contains 30 servings, meaning this supplement would cost you $1.50 per day.

6. YourBiology — best probiotics for IBS with a wide range of strains


By delivering 20 billion CFU of 10 different strains of “good” bacteria, this YourBiology supplement may improve digestion, reduce bloating, cramping, and flatulence. Furthermore, 3 types of digestive enzymes were added to this product for additional digestive system support.

YourBiology also features vitamin D, which is often associated with digestive health. Although the research studies showed mixed results, supplementation of this vitamin may reduce the symptoms of IBS in cases of deficiency. Moreover, some studies indicate that people with IBS may be more prone to reduced levels of vitamin D.

One 30-day supply bottle of YourBiology is priced at $79.99, making it $2.67 per day. Keep in mind that this brand offers a 60-day refund policy.

7. Purovitalis — best supplement for IBS featuring vitamin D


Another popular ingredient in IBS supplements is vitamin D. As some research studies suggest, vitamin D may reduce the severity of IBS symptoms. However, the evidence is mixed, and further research is needed to confirm the effect of vitamin D on IBS patients. If you opt for a vitamin D supplement, Purovitalis is worth considering.

This supplement features vitamin D3 — commonly referred to as a more potent version of vitamin D compared to the vitamin D2 form used in supplements. One serving of Purovitalis would provide you with 50 mcg/2000 IU of vitamin D3. Moreover, this supplement employs liposomal delivery to enhance the bioavailability of the vitamin.

Currently, one bottle of Purovitalis is priced at $20.00. As it contains 60 servings in total, this supplement would cost you $0.34.

Comparison of the best supplements for IBS

Product Ingredients for IBS symptomsPricePrice per servingMore information about the brand
UnbloatProbiotics$65.95$2.20Unbloat review
RoutineProbiotics$39.95 $1.33 Routine review
VSL#3Probiotics $65.95$1.10–$2.20VSL#3 probiotics review
RitualProbiotics $54.00 $1.80Ritual review
OweliProbiotics$44.99 $1.50 N/A
YourBiologyProbiotics and vitamin D$79.99$2.67YourBiology review
PurovitalisVitamin D$20.00$0.34N/A

What is IBS and do I have it?

Irritable Bowel Syndrome (IBS) is a common chronic functional disorder that affects the gastrointestinal tract. Although the symptoms will vary from person to person, the most common are bloating, abdominal pain, diarrhea, or constipation.

However, if you have these or similar symptoms, it does not automatically mean you have IBS, as these symptoms could be caused by other factors such as overeating, low fiber intake, and several other conditions.

If you suspect you may have IBS, it is crucial to seek advice from your healthcare provider. A doctor will perform a thorough examination to confirm or rule out IBS or other potential underlying conditions.

There is no cure for IBS, but there is a wide range of management strategies people can employ to reduce IBS symptoms. Most people can control their symptoms by improving their diet and lifestyle. For instance, dietary modifications can include identifying and avoiding specific foods that trigger IBS symptoms. The management plan will be discussed with your doctor after getting the diagnosis.

IBS symptoms

IBS symptoms will vary from person to person. The most common include abdominal pain, bloating, gas, and changes in bowel habits. Moreover, there are 3 types of IBS that differ in symptoms.

  • IBS with constipation (IBS-C). The most common concern for individuals with IBS-C is constipation.
  • IBS with diarrhea (IBS-D). This type of IBS is defined by frequent episodes of diarrhea.
  • Mixed IBS (IBS-M). If you have this type of IBS, you may experience both constipation and diarrhea.

Tips on how to choose the right IBS supplement

If you have decided to start taking supplements to manage your IBS symptoms, there are a few things that are important to keep in mind before you purchase any product.

  • Identify your symptoms. Since supplements can not treat or cure IBS, only to help relieve certain symptoms, identify what issues or concerns you would like to address by taking OTC supplements for IBS. Ideally, you should discuss this with a registered dietitian or medical practitioner before you choose the supplement.
  • Consider the ingredients. Certain active ingredients in supplements may be more beneficial for IBS than others. For instance, probiotics for IBS may help to relieve certain symptoms that are common complaints for people with IBS: bloating, flatulence, and diarrhea.
  • Consult your physician. If you decide to incorporate IBS supplements into your routine, it is advisable to consult with a healthcare professional. They can help you choose the best supplements for IBS according to your diagnosis.

Are IBS supplements safe?

The safety of IBS supplements will depend on the active ingredients and the individual's health status.

For instance, probiotics are one of the most common ingredients of IBS supplements. Probiotics are generally considered to be safe. However, some individuals, including people with compromised immune systems, should avoid taking them

Furthermore, IBS supplements may cause side effects, but they are generally mild. The most common side effects include symptoms such as diarrhea, stomach pain, or nausea. These symptoms usually resolve after a couple of weeks of regular use.

Check the label of the supplement you are considering purchasing. Some IBS supplements may include essential minerals and vitamins that could be in levels that are too high and lead to adverse effects in your individual case. For this reason, it is important to discuss with a healthcare professional if you should incorporate supplements in your routine.

IBS supplements vs. dietary changes

Dietary changes are usually the first step in IBS management. The most commonly prescribed dietary strategy for IBS is a low-FODMAP diet. Moreover, lifestyle changes should be considered as well. Most people can cope with IBS by improving their diet, lifestyle, and reducing their stress levels.

If permitted by the supervising healthcare professional, IBS supplements may be also introduced. As there is no cure for IBS, people diagnosed with this syndrome focus on effectively managing their symptoms, and some of the supplements may offer that. For instance, probiotics may be helpful for some in reducing bloating, diarrhea, constipation, and flatulence.

People with IBS may also be at risk of certain vitamin and mineral deficiencies. For instance, some studies suggest that not only people with IBS are more likely to develop deficiencies in vitamin D, but supplementation of it may reduce the severity of some of the IBS symptoms. It is worth mentioning that some research studies on vitamin D and IBS showed mixed results suggesting that it may not have any effect on IBS patients. If you suspect you may have a deficiency in certain vitamins or minerals, consult your healthcare provider for further evaluation.

Maintaining gut health with supplements for IBS

Certain supplements for IBS may be beneficial for maintaining gut health.

For instance, probiotics are an important factor in keeping your gut healthy. These beneficial bacteria, naturally present in the human body, contribute to such functions as digestion. If you have a disbalance in your gut microbiota, you may have such symptoms as bloating, upset stomach, diarrhea, and constipation — resembling those observed in individuals with IBS.

Probiotic supplements may balance out your gut microbiota and thus reduce the mentioned symptoms. Keep in mind that you can also acquire probiotics through diet, as there is a myriad of food products that contain “good” bacteria, such as yogurt, kimchi, sauerkraut, other pickled vegetables, and kefir.

Another important factor to be considered is dietary fiber — carbohydrates that are not digestible by humans. Although their benefits are often overlooked, fiber is essential in our diets as it promotes regular bowel movements and prevents constipation. After discussing the best IBS management strategy with a registered dietitian, people with IBS could benefit from increasing their fiber intake if they do not meet the recommended 25 grams of fiber target per day. One review concluded that supplementation with fiber, particularly psyllium, may help to reduce IBS symptoms.

Supplements should not be used in place of a well-balanced diet, but they may help support one’s health when incorporated as part of a holistic approach.

Other products that target bloating and constipation

Best probiotics for IBS that may alleviate such symptoms as flatulence, bloating, and upset stomach.

If you are looking for remedies for bloating, discover our best probiotics for bloating.

If constipation is your main concern, check out the best probiotics for constipation.

If you are a woman experiencing IBS symptoms, consider the best probiotics for women.

Discover a variety of supplements designed to reduce bloating.


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