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Best Supplements for Muscle Growth: Top 5 Brands Reviewed

Supplements for muscle gain are specially formulated products designed to enhance muscle growth and improve workout performance. They may provide essential nutrients required to repair and build muscle tissue. These supplements can be a valuable addition to a balanced diet and a structured exercise regimen, offering potential benefits like increased muscle mass, strength, and faster recovery times.

In this article, we will review our choice of top 5 products for supporting muscle gain.

Best supplements for muscle growth: shortlist

  1. A Quality Life — best pre-workout supplement
  2. XWERKS — best whey protein supplement
  3. Transparent Labs — best recovery supplement for vegans
  4. TestoPrime — best supplement for increased energy
  5. Immune Tree — best supplement for enhanced performance

How we compiled our list of the best supplement brands for muscle growth

To compile our list of the best supplements for muscle gain, we conducted a thorough evaluation based on several key criteria.

Provider reputationCustomer reviews and ratings
IngredientsScience-based, sufficiently researched
Third-party testingIndependent laboratory certification
Price-dosage ratioComparing the price and quantity
  • Provider reputation. We selected reputable brands with a history of consistently delivering top-tier products. We acknowledged the significance of customer feedback and reviews in understanding the contentment and encounters of other users.
  • Ingredients. We analyzed the ingredients of each product, emphasizing natural and organic components while avoiding artificial additives.
  • Third-party testing. We prioritized products that undergo rigorous third-party testing. This testing ensures that the supplements meet the highest standards of quality, purity, and safety, providing consumers with assurance.
  • Price-dosage ratio. We sought supplements with good value for money for the quantity of each product.

Best supplements for muscle growth: an overview

In creating this list, we assessed a variety of brands and products dedicated to muscle gain.

Selecting a premium product designed for particular needs is crucial. While there might be similarities among various muscle growth supplements, each has its unique composition that offers unique benefits. It's essential to understand this distinction when addressing particular health goals.

The products in this list are organized based on their individual benefits, ingredients, and other features. Additionally, the list explores the pros and cons associated with each product.

1. A Quality Life — top pre-workout enhancer


Pre Workout Fruit Punch by A Quality Life Nutrition is a supplement specifically designed for athletes aiming to achieve peak performance in their workouts.

This meticulously crafted supplement contains key ingredients such as arginine AKG, creatine, beta-alanine, and caffeine, which may enhance endurance and ensure optimal results during training sessions. The unique blend of these ingredients may not only boost energy levels but also help achieve better workout results.

The supplement contains 30 servings (217.5 g) with a single serving size of 1 scoop (7.25 g).

The product is USDA-organic, GMP-certified, and undergoes third-party lab testing to ensure purity and potency.

Pre Workout Fruit Punch is priced at $62.95. It's worth noting that the website offers free shipping storewide, adding to the product's value proposition.

2. XWERKS — leading whey protein product

Xwerks grow

Grow by XWERKS is a premium whey protein isolate designed to support muscle growth, repair, and strengthen the immune system.

One of its standout features is its low-carb, keto-friendly formulation which is suitable for individuals adhering to specific dietary requirements. According to the website, the protein in the product is derived from cows that graze naturally in New Zealand, a country known for its strict dairy quality standards, ensuring no hormones, antibiotics, or pesticides are passed on to the consumer.

A single container of the product includes 30 servings (907 g), with a single serving size of 1 scoop (30 g).

Based on the brand’s claims, the supplement is non-GMO, gluten-free, and undergoes a unique microfiltration process, preserving essential nutrients while eliminating unwanted fats and carbohydrates. This process results in a protein-rich formula with 25 g of protein and over 6 g of BCAAs (branched-chain amino acids) per serving.

The product is priced at $59.00 USD, with a subscription option available for savings.

3. Transparent Labs — best post-workout solution for vegans

Transparent Labs BCAA

BCAA Glutamine by Transparent Labs is a supplement designed to enhance muscle recovery, endurance, strength, and overall training performance.

According to the provider, this product is enriched with a 2:1:1 ratio of fermented vegan BCAAs, L-glutamine, L-valine, and vitamin C.

A single container of the supplement includes 30 servings (590 g) with a single serving of 1 scoop (19.60 g).

BCAA Glutamine is available in multiple flavors without any artificial sweeteners, dyes, or fillers. The product is also gluten-free, non-GMO, and devoid of artificial preservatives.

Transparent Labs emphasizes its commitment to quality, ensuring all its products, including BCAA Glutamine, undergo third-party lab testing.

The product is priced at $39.99, with subscription options available for additional savings.

4. TestoPrime — optimal vitality-boosting supplement

Testo Prime Instant Energy

Instant Energy by TestoPrime is a specialized energy solution designed for men facing demanding lifestyles. According to the brand, this product may offer a consistent energy boost without the typical jitters or caffeine crash. It aims to enhance energy, mental clarity, mood, and overall performance.

The product's unique blend includes ingredients such as caffeine anhydrous, L-theanine, L-taurine, L-tyrosine, B vitamins, L-choline bitartrate, KSM 66® ashwagandha extract, and vitamin C.

A single container includes 30 servings (210 g) with a single serving of 1 sachet (7 g).

Instant Energy is soy-free, gluten-free, vegan, and made in the USA. The product undergoes third-party testing and is produced in a GMP-certified facility with FDA-approved ingredients, ensuring quality and effectiveness.

As for the pricing model, customers can opt for a one-time purchase at $44.99 or a monthly subscription at $35.99, which offers a 20% discount. Every order is backed by a 100% satisfaction, lifetime guarantee.

5. Immune Tree — best supplement for enhanced performance

Immune Tree Flex6 Fitness Formula

Flex6 Fitness Formula by Immune Tree is a fitness supplement designed for athletes and fitness enthusiasts. It may enhance athletic performance and speed up recovery.

The formula is enriched with several potent ingredients:

  • Bovine colostrum, which may offer anti-aging benefits
  • DIM (diindolylmethane), which may promote optimal estrogen and testosterone levels
  • Creatine ethyl ester HCL, which may enhance energy and workout performance
  • 5-methyl-7 methoxy-isoflavone, which offers potential steroid-like effects without side effects

Flex6 Fitness Formula contains 180 capsules per bottle with a recommended dosage by the manufacturer of 3 capsules per day.

The product is available for $73.75 with free USA shipping for orders over $99.00.

Comparison of the best supplement brands for muscle growth

BrandBrandPrice per servingServing sizeServings per container
A Quality Life$62.95$2.101 scoop30
XWERKS$59.00$1.971 scoop30
Transparent Labs$39.99$1.331 scoop30
TestoPrime$44.99$1.501 sachet30
Immune Tree$73.75 $1.233 capsules60

A deep dive into top supplements for muscle building

Muscle building requires a combination of consistent training and a proper diet. To enhance these efforts, certain supplement types are recognized for their effectiveness in promoting muscle growth. These supplements not only support muscle development but also may boost performance and recovery.


Creatine is a naturally occurring compound formed during energy metabolism. It plays a pivotal role in supplying energy to muscles. It's known to improve exercise performance, increase muscle mass, and provide cellular energy, making it a favorite among athletes and bodybuilders. It is also particularly known for the loading phase process, which supplies the muscles with a higher intake of creatine for a brief period of time.

Whey protein

Whey protein is a high-quality protein derived from milk during cheese production. It's rich in essential amino acids, which are vital for muscle repair and growth. Consuming whey protein after workouts can significantly enhance muscle protein synthesis and promote muscle growth. It's a staple in the fitness community due to its rapid absorption rate and ability to provide the body with the necessary building blocks for muscle development.

Essential amino acids (EAAs)

EAAs are amino acids that the body cannot produce on its own. They play a pivotal role in muscle protein synthesis and repair. Supplementing with EAAs can prevent muscle breakdown and promote muscle growth, especially when combined with resistance training. These amino acids are the foundation of protein, and their intake is crucial for those looking to optimize muscle growth and repair.


Beta-alanine is a non-essential amino acid that helps produce carnosine, a compound that plays a role in muscle endurance during high-intensity exercise. By increasing carnosine levels in muscles, beta-alanine can help delay muscle fatigue and improve overall workout performance. It's especially beneficial for athletes participating in long-duration activities where endurance is key.

Beta-hydroxy-beta-methylbutyrate (HMB)

HMB is a compound that results from the breakdown of the amino acid leucine. It's known to reduce muscle protein breakdown and enhance muscle gain. HMB is particularly effective in preventing muscle loss during periods of muscle-wasting conditions or reduced calorie intake. It acts as a protective agent, ensuring the muscles remain intact even under stressful conditions.

A guide to choosing the right supplements for muscle gain

Building muscle involves more than just lifting weights. The proper diet, together with the right supplements, can enhance your efforts, but choosing them requires careful consideration. Here's a guide to help you make informed decisions tailored to your needs.

  • Diet. Some ingredients in the supplements are naturally found in foods. For instance, creatine is abundant in meat. However, vegans might have lower creatine levels due to their dietary restrictions. It's essential to understand your diet and identify if you're missing out on any muscle-building nutrients naturally before turning to supplements.
  • Age. A person’s age plays a significant role in muscle development. Older individuals might face challenges like reduced appetite and loss of muscle mass. Supplements may help counteract these effects, ensuring that seniors get the necessary nutrients to support muscle health and growth. Tailor your supplement choices to age-specific needs for best results.
  • Form. Supplements come in various forms, including powders, liquids, and pills. Powders can be mixed with water or shakes, pills might be more convenient for those on the go, and liquids may offer faster absorption. Your lifestyle and preferences will determine the best form for you.
  • Ingredients & potential interactions. Always pay close attention to the ingredient list. Some supplements, like those containing caffeine, might interfere with sleep or other medications. It's crucial to be aware of any potential interactions with medications or other supplements you're taking. Ensure the product is safe and consult with a healthcare professional before starting.

Supplements for muscle growth for casual fitness enthusiasts vs. bodybuilders

Muscle growth supplements cater to different needs, depending on whether they are for casual fitness enthusiasts or competitive bodybuilders. The distinction lies in the goals, intensity of workouts, and desired outcomes. Here's a breakdown of the differences based on casual fitness vs. professional muscle gain:

  • If you are interested in building muscle non-competitively. Casual fitness enthusiasts often focus on general health and aesthetics. Supplements might be consumed in moderate dosages. For instance, protein shakes might be taken post-workout, and creatine could be used as well, but in lower doses than bodybuilders. The frequency typically aligns with workout days, ensuring muscle recovery without over-supplementation. It's essential to strike a balance between muscle growth and overall well-being.
  • If you are a bodybuilder. Competitive bodybuilders have rigorous training regimens and specific physique targets. They often consume supplements in higher doses, including creatine, branched-chain amino acids (BCAAs), and pre-workout formulas. Timing is paramount, with strict schedules for supplement intake to optimize results. Given the intense nature of bodybuilding workouts, there's a significant emphasis on supplements that aid in rapid recovery and reduce muscle breakdown.

Supplements are not enough: a good diet and an exercise regime are key

While supplements may enhance muscle growth and recovery, they are not a standalone solution. A balanced diet of nutritious foods provides essential nutrients that supplements can't replicate entirely. For example, beetroot juice has shown benefits that may help improve athletic performance.

Other factors include regular exercise, which ensures that the body utilizes these nutrients effectively for muscle growth, and rest and sleep, which are crucial for muscle recovery and general well-being. For instance, taking creatine requires increased water intake to prevent dehydration and kidney strain. Thus, a holistic approach, combining diet, exercise, and adequate rest, is indispensable for optimal health and muscle growth.

Supplements for muscle growth: side effects and interactions

While supplements for muscle growth may contain many benefits, they can also have potential side effects and interactions. Overconsumption of amino acids may lead to energy surplus, while certain vitamins and minerals may lead to toxicity, affecting organs like the liver and kidneys. It's also crucial to be aware of interactions between supplements and medications. For instance, some muscle-building supplements can reduce the effectiveness of certain drugs or exacerbate their side effects.

Always consult a healthcare professional before starting any supplement regime and ensure a balanced approach to muscle growth, prioritizing safety.

Read more about supplements for health support

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Best spermidine supplements are a great choice if you need an energy boost

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