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Best Supplements for Osteoarthritis: Our Top 5 Choices This Year

Navigating the complex world of supplements for osteoarthritis can be daunting. This article delves into our top five choices, each selected based on ingredient quality, scientific backing, and user feedback.

We'll explore how ingredients like vitamin D, omega-3s, and specialized collagen formulations may help manage symptoms and enhance joint health.

With careful consideration of formulation bioavailability and third-party testing, these supplements stand out as promising options for those seeking natural support in their journey to alleviate the discomfort of osteoarthritis.

Best supplements for osteoarthritis: a shortlist

  1. Natural Stacks — best supplement for osteoarthritis with curcumin
  2. Performance Lab — best supplement for osteoarthritis with omega-3
  3. Purovitalis — best supplement for osteoarthritis with vitamin D3
  4. Utzy — best supplement for osteoarthritis with collagen
  5. BATCH — best product for osteoarthritis with CBD

How we compiled our list of best supplements for osteoarthritis

When selecting the best supplements for osteoarthritis, it's essential to consider several criteria to ensure safety and potential efficacy. Here is a concise table outlining these key considerations:

SafetyQualityScientific supportPersonal needs
Ingredients with minimal side effects
High manufacturing standardsBacked by researchSpecific to individual health
  • Safety. It's crucial to choose supplements with ingredient dosages that have a track record of being safe with minimal side effects. Always consult with a healthcare provider, especially if you have underlying health conditions or are taking other medications.
  • Quality. Opt for supplements from reputable brands that adhere to high manufacturing standards. This ensures the product is free from contaminants and contains the advertised ingredients.
  • Scientific support. Look for supplements that have been shown in clinical studies to alleviate the symptoms of osteoarthritis. Give preference to supplements that have some level of scientific support.
  • Personal needs. Consider any personal allergies or sensitivities. For instance, if you're looking for best supplements for osteoarthritis in the hands, you might prioritize formulations designed for hand joints.

Best supplements for osteoarthritis: an overview

Naturally, the question of "What supplements are good for osteoarthritis?" arises. Exploring the best supplements for osteoarthritis requires careful consideration of their potential to ease joint discomfort and enhance overall joint health. In this overview, we will evaluate five providers, scrutinizing their offerings against critical criteria such as ingredient efficacy and safety, product quality, scientific support, and suitability for personal health needs. This will guide those affected by osteoarthritis in making informed decisions tailored to their specific conditions, like osteoarthritis in the hands or knees.

1. Natural Stacks — best supplement for osteoarthritis with curcumin

Natural Stacks Turmeric

Natural Stacks Turmeric, featuring a curcumin extract enhanced with coconut oil, positions itself as a bioavailable supplement, potentially beneficial for osteoarthritis management. Its use of NovaSOL® Curcumin, claimed to be significantly more bioavailable than standard curcumin, makes it a potent choice for curcumin benefits alleviating joint discomfort and supporting joint health.

The addition of coconut oil not only has the potential to aid in absorption but may also contribute additional health benefits. This product is designed to support not just joint health but also may also support cognitive function and metabolic health, making it a versatile supplement. The product's diverse health claims, including digestive and cardiovascular support, are compelling. Yet, it's the NovaSOL® Curcumin formulation that distinguishes it, promising enhanced bioavailability and, potentially, superior efficacy compared to other curcumin options.

The positive customer reviews and third-party testing add credibility to the brand's trustworthiness and claims. However, the specific benefits for osteoarthritis should be considered in the context of individual health needs and in consultation with a healthcare provider.

30-day supply costs $34.95 ($1.17 per serving).

2. Performance Lab — best supplement for osteoarthritis with omega-3

Performance Labs Omega3

Performance Lab® Omega-3, with its comprehensive omega-3 fatty acid profile, including EPA and DHA, is tailored for those managing osteoarthritis, offering a plant-based source from algal oil. This vegan-friendly supplement is designed to support joint and bone health.

EPA and DHA are known for their anti-inflammatory effects, which are beneficial in addressing joint inflammation and pain associated with osteoarthritis. They may also contribute to the health of cell membranes, potentially improving joint function and comfort.

The brand's claims of the supplement's role in easing joint stiffness and supporting bone density are in line with research on the benefits of omega-3s for osteoarthritis. Despite positive customer feedback, the lack of third-party testing data and unspecified GMP certification may require cautious consideration from consumers seeking the highest standards of supplement verification.

30-day supply costs $49.00 ($1.63 per serving).

3. Purovitalis — best supplement for osteoarthritis with vitamin D3


Purovitalis Liposomal Vitamin D3 is tailored for those seeking to support their bone health — a crucial aspect when managing osteoarthritis in vitamin D3 deficiency cases.

Purovitalis offers a liposomal delivery system designed for enhanced absorption, potentially offering more direct benefits to bone strength and immune function. This could be particularly beneficial for individuals with osteoarthritis, as vitamin D is essential for calcium absorption and joint health, and users may observe a marked improvement in the osteoarthritis symptoms if their vitamin D3 levels are low.

The product's third-party testing and GMP certification add credibility to its quality claims. While customer reviews are positive, the small number suggests a need for a broader user consensus to ensure its anecdotal effectiveness.

60-day supply of 2000 IU-strength vitamin D3 costs $20.00 ($0.33 per serving).

4. Utzy — best supplement for osteoarthritis with collagen

Utzy Coll-U-Gen

Utzy Naturals Coll-U-Gen stands out for those with osteoarthritis, offering a specialized combination of gelatin hydrolysate and collagen aimed at enhancing joint health. Although not an option for vegetarians or vegans because of its animal-based ingredients, the clinically studied UC-II® collagen in this supplement has shown promise in repairing connective tissue, which is crucial for osteoarthritis management.

The inclusion of native, non-denatured type II collagen is significant, as it may help maintain joint health and assist in alleviating joint discomfort. Fortigel® technology further refines the product by ensuring the collagen particles are optimally sized for the body to use in the restoration of joint tissue.

The product's powder form can offer flexibility in how it's consumed.

24 servings cost $47.50 ($1.98 per serving).

5. BATCH — best product for osteoarthritis with CBD


BATCH Original CBD Oil tincture, with its blend of terpenes and organic hemp extract, positions itself as a versatile all-purpose CBD solution, potentially beneficial for those managing osteoarthritis.

The presence of beta-caryophyllene, linalool, and limonene terpenes may enhance the anti-inflammatory and analgesic properties of the tincture, which could help alleviate joint pain and inflammation associated with osteoarthritis. The hint of mint flavor may offer a pleasant taste, making regular use more enjoyable.

The product is third-party tested, which is a strong endorsement of its quality, and the excellent customer reviews suggest that many users have found it effective. The tincture form allows for easy dosage adjustments with the included dropper.

30 ml of tincture costs $44.99 ($0.75 per 0.5 ml serving).

Comparing the best products for osteoarthritis

BrandPrice per bottlePrice per servingServings per bottleFormNumber of active ingredients
Natural Stacks$34.95$1.1730Softgel1
Performance Lab$49.00$1.6330Softgel1
$47.50$1.98 24Powder2

What is osteoarthritis?

Osteoarthritis is a degenerative joint disease characterized by the breakdown of cartilage — the cushioning material between bones. As cartilage wears away, bones may rub against each other, leading to pain, swelling, and reduced mobility. This condition commonly affects joints in the hands, knees, hips, and spine.

While it's often associated with aging, other factors like genetics, obesity, and joint injuries can contribute to its development. Osteoarthritis is a progressive condition, meaning it can worsen over time, but certain interventions may help manage symptoms and improve joint function.

How can supplements help with osteoarthritis?

Supplements may offer supportive benefits for individuals with osteoarthritis by potentially easing symptoms and supporting joint health. Here's how certain key components in these supplements might assist:

  • Natural anti-inflammatory agents. These may help soothe inflammation in the joints, which may reduce pain and swelling, offering a more comfortable range of motion.
  • Essential fatty acids. Known for their inflammation-modulating properties, they may decrease morning stiffness and tender joints, contributing to improved daily function.
  • Bone health nutrients. They are crucial for maintaining strong bones and joint function, which might help in lessening the discomfort associated with degenerative joint conditions.
  • Cartilage building blocks. By possibly supporting the maintenance of cartilage, these components can be vital in preserving joint integrity and mobility.
  • Plant-derived compounds. Emerging evidence suggests plant compounds, such as CBD, might play a role in pain management, potentially offering a natural means to enhance comfort and joint movement.

These benefits collectively aim to maintain joint flexibility, reduce discomfort, and improve the quality of life for those dealing with osteoarthritis.

Active ingredients that have an effect on osteoarthritis

One might wonder "What natural supplements are good for osteoarthritis?" In the management of osteoarthritis, certain active ingredients are recognized for their potential to reduce specific symptoms and enhance joint health. These components, ranging from vitamins to herbal extracts, may offer a spectrum of benefits that extend beyond joint care to overall well-being.

Vitamin D

For those with vitamin D deficiency, Vitamin D3, a form of vitamin D, may aid in the maintenance of joint health and mitigate osteoarthritis symptoms by preserving bone and cartilage integrity. It's also pivotal for calcium absorption, crucial for bone strength, and supports the immune system. Additionally, vitamin D3 has been associated with improved muscle function and a potential reduction in the risk of developing chronic diseases, encompassing a broad spectrum of health benefits.


Ginger contains bioactive compounds that may help reduce inflammation and pain associated with osteoarthritis, potentially improving joint mobility. Beyond joint health, ginger is renowned for its digestive benefits, helping to ease nausea and promote gastric motility. Its antioxidant properties also support the immune system and may protect against chronic diseases by mitigating oxidative stress, offering comprehensive health advantages.


Curcumin, the active component of turmeric, may help manage osteoarthritis by reducing inflammation and joint pain, potentially improving function and mobility. Beyond joint health, curcumin is noted for its antioxidant properties, which may protect cells from damage and support brain health. It's also being researched for its potential role in heart health, mood regulation, and as a preventive agent against certain chronic conditions, making it a compound of interest for overall wellness.


Collagen, a primary protein in joint cartilage, may help in the management of osteoarthritis by supporting cartilage health and possibly slowing degenerative changes. It's also vital for skin elasticity and strength, contributing to a youthful appearance. Additionally, collagen plays a key role in maintaining the structure of tendons and ligaments, which is essential for mobility and stability, thereby offering benefits that extend to the broader musculoskeletal system. Read more on collagen supplements in our deep dive article.


Omega-3 fatty acids may benefit individuals with osteoarthritis by reducing inflammation and joint pain, potentially aiding in improved mobility and quality of life. These essential fats are also critical for heart health, helping to regulate cholesterol levels and maintain cardiovascular function. Moreover, omega-3s support brain health, contribute to cognitive function and mental well-being, and have been associated with a lower risk of depression, showcasing their extensive health-promoting properties.


CBD, or cannabidiol, may offer relief in osteoarthritis by diminishing inflammation and discomfort in the joints, which can enhance mobility and daily functioning. Beyond its potential for joint health, CBD is explored for its anxiolytic and neuroprotective properties, which may reduce anxiety and support mental well-being. Additionally, its possible benefits for sleep patterns and pain management make it a compound of interest for holistic health improvement.

Supplements for osteoarthritis: dosage and usage recommendations

When considering supplements for osteoarthritis, it's important to understand that their onset of action and efficacy can vary. Typically, consistent use over several weeks or months is necessary to gauge effectiveness. Dosage should align with healthcare provider recommendations or product guidelines. Monitoring joint pain, stiffness, and mobility can help assess if a supplement is beneficial.

It's also crucial to note that supplements should complement, not replace, conventional treatments and a healthy lifestyle.

Side effects and considerations

Supplements for osteoarthritis, while beneficial for some, can pose risks due to interactions with prescription medications and underlying health conditions. For instance, supplements like omega-3 fatty acids may increase bleeding risk when taken with blood thinners such as warfarin. Similarly, certain supplements can interact with anti-inflammatory medications, leading to increased side effects or diminished medication efficacy.

Individuals with liver or kidney conditions should exercise caution, as some supplements can exacerbate these issues. For example, high doses of vitamin D can cause harm in those with kidney disease and lead to hypervitaminosis D, and some herbal supplements can be hepatotoxic.

Allergies to supplement ingredients are another concern, as they can lead to severe reactions. It's crucial for individuals to discuss their full medical history with a healthcare provider, including any known allergies, to avoid adverse effects. Always follow professional guidance on dosage and monitor for any unusual symptoms when starting a new supplement.

Other ways to manage osteoarthritis symptoms

Managing osteoarthritis symptoms extends beyond supplements and medication, incorporating a variety of lifestyle and therapeutic strategies. Physical activity is paramount low-impact exercises such as swimming or walking may maintain joint flexibility and strengthen the muscles supporting the joints. Weight management is also crucial, as excess body weight can increase stress on weight-bearing joints, exacerbating pain.

Physical therapy can provide tailored exercises that enhance range of motion and joint function. Occupational therapy helps individuals adapt their daily activities to reduce strain on affected joints. Additionally, the use of assistive devices like braces or shoe inserts can improve joint alignment and relieve discomfort.

Mind-body practices such as yoga and tai chi can improve balance and reduce mental stress, which may indirectly help manage pain. Lastly, applying heat or cold to sore joints can temporarily ease pain and stiffness. These approaches, when combined with medical treatments, can significantly improve the quality of life for those with osteoarthritis.

Best supplements for osteoarthritis — our conclusion

In conclusion, while the best supplements for osteoarthritis — like those containing vitamin D, ginger, curcumin, collagen, omega-3, and CBD — may offer supportive benefits, they should be chosen with care, considering efficacy, safety, and personal health needs.

Alongside these supplements, a holistic approach, including exercise, weight management, and physical therapies, can provide comprehensive management of osteoarthritis symptoms.

Always consult healthcare professionals before beginning any new supplement to ensure safety and appropriateness for your health condition.

Further reading

Discover the best collagen for joints to reduce joint discomfort and stiffness.

When dealing with joint pain, discover the 9 things to stop doing if you have arthritis.

Read our deep dive into the best joint pain supplements to help with osteoarthritis and associated pain.

If you are curious about how CBD may alleviate osteoarthritis symptoms, read our article on the best CBD for knee pain and joint pain.


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