The Best Supplements for PCOS Management: 5 Brands Reviewed

PCOS, short for polycystic ovary syndrome, is a common health difficulty affecting 5–10% of women of reproductive age. Symptoms, such as insulin resistance, irregular menstrual cycles, or weight gain, may be addressed with certain medications or lifestyle changes.

However, women reluctant to start a prescription treatment may be looking for supplements to take for PCOS.

Hence, we analyzed the market and delved into the research of certain supplements to compile a list of the best over-the-counter PCOS supplements that might help ease some related symptoms.

Best supplements for PCOS: shortlist

• Nature’s Craft — best PCOS supplement for weight loss
• PartiQlar — best PCOS supplement for hormonal balance
• VitalityPRO — best supplement for heart health in PCOS
• Femometer — best PCOS supplement for ovulation
• Purovitalis — best vitamin supplement for PCOS

How did we compile our list of best supplements for PCOS?

To compile our list of the top PCOS supplements that may be suitable for specific needs and preferences, we took into consideration the following quality criteria.

Criteria	Description
Third-party testing	Independent lab testing
Dosage	Scientifically proven to be safe
Ingredients	Backed by science
Price per serving	$0.03–$0.75

• Third-party testing. We looked for PCOS supplements approved as safe and free from contaminants by third-party labs.
• Dosage. Top-rated PCOS supplements on our list come in adequate doses that were scientifically tested to be safe.
• Ingredients. The products on our list of best are formulations of science-backed ingredients that are suggested to be effective in improving insulin sensitivity, irregular ovulation, and other PCOS-related symptoms.
• Price. Aiming to provide you with the most cost-effective options, we have selected the supplements available on the market with affordable prices ranging between $0.70–$1.00 per daily serving.

Best supplements for PCOS: overview

Every woman's body is different, and there is no one-fits-all supplement option. Thus, your initial step before buying any PCOS product is to consult your OB-GYN to determine what might work best for you and your health needs.

Once you’ve learned more about your health difficulties and needs, you can check the products in this detailed overview of the commonly used supplements good for PCOS.

1. Nature’s Craft — best PCOS supplements for weight loss support

Try Nature's Craft now

Nature’s Craft Myo & D-Chiro-Inositol is intended for women’s wellness. Inositol was measured in studies with women having PCOS and demonstrated to improve fat metabolism, as well as improved brain function.

The manufacturer claims to use clean, science-backed, non-GMO, and natural ingredients. Above all, the company gives priority to safety by conducting third-party testing.

Nature’s Craft PCOS supplement for weight loss and mood enhancement has been produced in cGMP and FDA-approved facilities in the USA.

The provider suggests taking 4 capsules daily before a meal to improve regular cycles, fertility markers, and blood sugar balance. Each serving will provide you with 200 mg of choline, 1000 mg of Myo-inositol, and 50 mg of D-chiro-inositol.

One bottle of Nature’s Craft PCOS supplement for women contains 120 capsules for 30 days of use and costs $22.77 ($0.76 per serving).

2. PartiQlar — best PCOS supplement for hormone balancing in women

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PartiQlar presents Pure Resveratrol supplements in capsules. Resveratrol is a powerful anti-inflammatory agent, suggested to benefit women with PCOS by balancing testosterone, LH, and DHEAS levels.

PartiQlar is a single-ingredient PCOS supplement, including a bioavailable trans-resveratrol form of the ingredient. This is also regarded as an anti-aging supplement that is believed to have some neuroprotective and anti-oxidant effects.

Pure Resveratrol supplement by PartiQlar is third-party tested and NSF-certified for its quality and safety. According to the provider, resveratrol in the supplement is of 99% purity. This supplement is also manufactured in cGMP and FDA-compliant facilities.

The recommended daily serving of PartiQlar PCOS supplement is 1 capsule offering 500 mg trans-resveratrol. One bottle contains 60 capsules serving 2 months.

A 2-month supply of PartiQlar Pure Resveratrol costs $36.99 ($0.62 per serving). Bigger discounts are available with multi-buy options.

3. VitalityPRO — best supplement for PCOS to support heart health

Try Vitality Pro Berberine now

Women with PCOS may be at risk of developing cardiovascular challenges. VitalityPRO Advanced Berberine supplement features a powerful alkaloid berberine known for its heart-protective and anti-inflammatory effects.

Scientific findings suggest that supplementation with berberine in women with PCOS may show some benefits in improving insulin sensitivity and fertility parameters.

Berberine itself has low bioavailability, thus, the scientists behind the VitalityPRO supplement added Milk thistle — believed to contribute to advanced supplement absorption.

To ensure the consumer gets a high-quality and safe supplement for addressing PCOS symptoms, the provider conducts third-party testing. As the published certificate of analysis suggests, berberine is 99% pure.

One bottle of VitalityPRO Advanced Berberine contains 120 capsules for 4 months of use — 1 capsule taken daily. Each serving contains 500 mg berberine and 125 mg Milk thistle.

You can get your Advanced Berberine supplements from VitalityPRO at $44.00 ($0.37 per serving).

4. Femometer — best PCOS supplement for ovulation and LH levels

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Femtometer is a women-oriented company offering Myo-inositol and D-chiro-inositol supplements to help women with PCOS support ovulation — potentially improving fertility.

As per research, combining D-chiro and Myo-inositol may improve ovulation and egg quality in women with PCOS by balancing hormonal and glycemic profiles.

The manufacturing process of Femometer Myo-inositol and D-chiro-inositol supplement is processed in FDA and cGMP-compliant facilities in the USA. The company claims that final products are third-party tested for quality and safety.

The recommended intake of Femometer supplement is 3 capsules daily with food. Each serving provides 2000 mg of Myo-inositol and 50 mg of D-chiro-inositol.

To help you catch your ovulation windows and LH levels, the brand offers a Fertility Health Kit — a pack of inositol + LH and HCG tests.

One bottle of Fomometer inositol supplements for PCOS comes with 90 vegetable capsules and costs $35.99 ($1.20 per serving).

5. Purovitalis — best vitamin supplement for PCOS management

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According to researchers, vitamin D deficiency is another risk factor for PCOS development, yet supplementation may help to lower the risks by contributing to improved insulin sensitivity. Purovitalis offers vitamin D3 supplements of certified quality to help women address PCOS.

The vitamin D3 supplement for women with PCOS comes in capsules, the bioavailability of which is enhanced with liposomal technology to increase the absorption rates of the ingredients.

The manufacturer of Purovitalis Liposomal Vitamin D3 claims to conduct third-party testing for the approved quality of its products. The supplement is also made in cGMP-certified facilities in the EU.

The daily recommended dosage of Purovitalis Liposomal Vitamin D3 is 1 capsule delivering 50 mcg/ 2000 IU. Note that this dose may be higher than the recommended daily allowance (RDA) for vitamin D, so consider the supplementation after a doctor's consultation.

A one-time purchase of Purovitalis vitamin D3 for PCOS costs $20.00 ($0.33 per serving).

Comparison of the best supplements for PCOS

Brand	Price	Price per serving	Serving size	Servings per bottle	Capsules/amount per bottle	Ingredients	Dosage per serving	Supplement form
Nature’s Craft	$22.77	$0.76	4 capsules	30	120 capsules	Choline, myo-inositol, D-chiro-inositol	200 mg, 1000 mg, 50 mg	Capsules
PartiQlar	$36.99	$0.62	1 capsule	60	60 capsules	Resveratrol	350 mg	Capsules
VitalityPRO	$44.00	$0.37	1 capsule	30	120 capsules	Berberine, Milk thistle	500 mg, 125 mg	Capsules
Femometer	$35.99	$1.20	3 capsules	30	90 capsules	Myo-inositol, D-chiro inositol	2000 mg, 50 mg	Capsules
Purovitalis	$20.00	$0.33	1 capsule	60	60 capsules	Vitamin D3	50 mcg/ 2000 IU	Capsules

What is PCOS and what causes it?

The leading cause of PCOS is hormonal imbalance. Women with PCOS usually have higher-than-normal levels of androgens (sometimes referred to as “male hormones” naturally present in lower amounts in females.

One such hormone is testosterone, the increased levels of which in women can cause excess body hair growth, deeper voice, infertility issues, acne, and PCOS.

Another reason for polycystic ovary syndrome is the genetic predisposition or unhealthy lifestyle. PCOS may demonstrate early symptoms after puberty or later in one’s 20s or 30s.

Women with PCOS are more likely to encounter insulin resistance — related to excess weight gain. Also, they are more prone to developing type 2 diabetes. PCOS is generally characterized by the lack of or irregular menstrual cycles and ovulation, causing most women to struggle with conceiving.

The benefits of taking supplements for PCOS

Taking PCOS supplements in addition to a balanced diet, regular exercise, and sleep patterns, women are suggested to experience the following benefits:

• More regular and less painful menstruation. Certain supplement formulations may help balance hormones and reduce inflammation, thus inducing regular and less painful periods.
• Healthy weight support. Inositol is one of the common ingredients in PCOS supplements suggested to influence insulin sensitivity supporting weight management when combined with a healthy diet and regular exercise.
• Ovulation. Specific supplements for polycystic ovary syndrome, such as inositols, may be beneficial for inducing ovulation and higher egg quality.

Remember that every woman's body is different and may react differently to supplements. Thus, a doctor’s consultation is a must in case of PCOS.

Ingredients to look for when choosing the best supplement for PCOS

If you are looking for vitamin supplements for PCOS, think of the below-discussed ingredients scientifically suggested to contribute to the associated symptoms of this condition.

Folic acid

Women at reproductive age, before and during pregnancy, are recommended to take folic acid (vitamin B9). Supplementation with folic acid is suggested to improve metabolic functions.

In conjunction with myo-inositol, folic acid has been observed to improve fertility rates in women with PCOS.

Omega-3

Although the research on omega-3 effectiveness for PCOS is ongoing, available data suggests that supplementation with these fatty acids may contribute to improved blood lipid levels and shrink intervals between periods.

A recent study conducted with women with PCOS demonstrated that 6 months of supplementation with 2 g of omega-3 fatty acid may help improve metabolic health and support regular menstrual cycles.

Inositol

According to research studies, inositol may have several benefits for PCOS — reducing testosterone levels, improving insulin sensitivity, and regular cycle length. This is one of the commonly recommended supplements by healthcare practitioners.

There is some evidence that inositol may also be an alternative to metformin for women who suffer from the side effects of the latter. Yet, the dosages and formulations in the research studies do not necessarily match those supplements available on the market, and any changes in your PCOS therapy regime should be discussed with a healthcare practitioner.

Other ways to manage PCOS symptoms

Supplements or prescription medications are not standalone means to manage polycystic ovary syndrome. You should consider a holistic approach to address fertility-related and health challenges.

Women with this health condition should follow a healthy, balanced diet that includes fish, beans, legumes, and nuts. Doctors often advise replacing high-carb foods with whole grains to help enhance insulin sensitivity.

Healthy body weight maintenance is another approach to reducing some of PCOS-related symptoms. Regular exercise is recommended for women with excess body weight.

Often, women with body weight below the normal range may also have PCOS — called lean PCOS — and struggle with gaining weight. In this case, a nutrient-dense and varied diet is recommended.

Best supplements for PCOS — conclusion

PCOS is characterized by anovulatory or irregular menstrual cycles, challenges maintaining healthy body weight, hirsutism, acne, and psychological difficulties. PCOS supplements are specifically designed products or single ingredients scientifically observed to own some promising benefits for this health condition.

Along with supplementation, you should initiate lifestyle changes to ease the PCOS-associated symptoms. Some of such changes are exercise, a healthy diet, as well as mindfulness activities.

Before administering any supplement formulation to address PCOS, women should talk to obstetrician-gynecologists.

More information about PCOS and supplementation

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Try the following approaches to increase fertility with PCOS.