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Best Whey Protein to Lower Cholesterol Levels in 2024

Incorporating whey protein into your diet may be a helpful way to increase your lean protein intake and lower your consumption of foods that cause high cholesterol. Some studies have also suggested it promotes healthy cholesterol levels.

Whey is a protein derived from milk during the process of making cheese. It contains all nine essential amino acids, making it a complete protein and low in saturated fats.

This guide explores our list of five leading whey protein powders using specific criteria, such as manufacturing standard, provider reputation, customer reviews, and price.

Best whey protein to lower cholesterol: a shortlist

  1. Primegenix — best grass-fed whey protein
  2. Transparent Labs — best choice of flavors for whey protein
  3. Kaged — best whey protein with digestive enzyme
  4. Onnit — best environmentally-friendly whey protein
  5. MTN OPS — best proprietary blend of milk and whey protein

How we compiled our list of the best whey proteins to lower cholesterol

Before purchasing a supplement, it’s always a good idea to research several aspects of the product to ensure it meets your standards and needs. While doing our research on the best protein shake to lower cholesterol, we decided on these key aspects on which to base our judgements.

Quality of the ingredientsManufacturing processReputation of the brand
Customer reviewsPrice
High-quality ingredients
Third-party and GMP certificationsKnown for being established and reputablePositive feedback from people$39.99–79.95
  • Quality of the ingredients. We looked for products that contain well-researched ingredients.
  • Manufacturing process. We chose manufacturers that meet the highest standards certifications (cGMP) and undergo third-party testing.
  • Reputation of the brand. We selected manufacturers who have been in the industry for a while and are known for producing quality products.
  • Customer reviews. We read through user feedback, looking for authentic experiences from people who had taken the whey protein supplements.
  • Price. We looked for whey protein brands that are cost-effective while not compromising on quality.

Best whey protein to lower cholesterol: an overview

The following list is our top five best whey proteins to lower cholesterol according to our previously decided criteria.

We include detailed information for each product so you can get a clear picture of the pros and cons of each supplement.

It’s our hope that you find this guide helpful in your search for a whey protein.

1. Primegenix — best grass-fed whey protein

PrimeGENIX® Pure Whey Protein Isolate

Primegenix Whey Isolate protein powder stood out to us for its high-quality whey derived from the milk of New Zealand grass-fed cows. We also love that their filtration process removes all unwanted sugars, fats, and carbs, producing one of the best protein powders for high cholesterol.

Primegenix offers two flavor options: chocolate and vanilla. The whey powder mixes easily and smoothly and dissolves quickly, so it doesn’t have a grainy texture.

The ingredients are clean and non-GMO, with no fillers, hormones, antibiotics, artificial colors, or flavors. They are also free of allergens such as lactose, gluten, yeast, and nuts. However, Primegenix does not display third-party testing results on its website.

Each container is 30 servings and costs $79.95. Amazon buyers rate this product with 4 stars out of 5.

2. Transparent Labs — best choice of flavors for whey protein

Transparent Labs Whey Protein Isolate

Transparent Labs 100% Grass-fed Whey Protein Isolate is another protein powder we had to have on our top five products list.

Transparent Labs lives up to its name with its clean ingredients. The whey isolate is derived from American-raised grass-fed cows without hormonal agents or growth hormones. It’s also free of artificial sweeteners, fillers, and food dyes.

You can choose from 14 flavors, or they offer an unflavored option as well. Transparent Labs is proud of its easy-to-mix whey protein and suggests adding it to a variety of recipes. We also love that their science-backed whey protein ingredients are third-party tested for purity according to the brand.

Customers on the Transparent Lab website rate this whey protein with 4.5 out of 5 stars. One container is 30 servings and costs $59.99.

3. Kaged — best whey protein with digestive enzyme

KAGED Whey Protein Isolate

Kaged Whey Protein Isolate stood out to us as an exceptional supplement with its high-quality whey protein and low lactose content. We also loved that Kaged included ProHydrolase, a digestive enzyme blend, into their protein blend for added digestion ease.

The filtration process Kaged uses during production removes all but one gram of sugar and most of the lactose, which is claimed to help reduce bloating.

Kaged produces high-quality products that meet the high standards of third-party testing and Informed-Sports Certification requirements.

The low cholesterol protein powder comes in four flavors: vanilla, chocolate, s’mores, and chocolate peanut butter. It is also available in two sizes: 1.8 pounds and 3 pounds.

A 1.8-pound container contains 25 servings and costs $39.99. Customers on the Kaged website rate this product 4.8 out of 5 stars.

4. Onnit — best environmentally-friendly whey protein

Onnit Whey Protein

Onnit Whey Isolate Protein deserves a spot on our list with its high-quality whey protein. The whey is derived from Irish dairy cows, where they can graze an average of 250 days a year. We love that their cows also meet Animal Welfare Approved standards.

The company is devoted to producing products that meet environmentally friendly standards and have received certifications from organizations such as the Rainforest Alliance and UTZ. Onnit also has their ingredients undergo third-party testing for quality assurance.

Customers on the Onnit website give this product a 4.3 out of 5 star rating.

The Onnit protein comes in two flavors: vanilla and Mexican chocolate. One package contains 30 servings and costs $59.95.

5. MTN OPS — best proprietary blend of milk and whey protein

MTN OPS Keep Hammering Protein Blend is a mix of milk and whey proteins. This proprietary blend is claimed to absorb immediately and over time to help with muscle repair and growth.

MTN OPS is a dedicated team of professionals who want to help improve the health of their customers, whether their goal is to boost their well-being, manage their weight, or build muscle.

We especially appreciate that for each purchase made through MTN OPS, a meal is donated through Conquer Hunger to a community and child in need.

The whey protein comes in a chocolate-caramel flavor. Each container is 30 servings and costs $54.95. Customers on the MTN OPS website rate this product with 4.8 out of 5 stars.

Comparing the best whey protein to lower cholesterol

ProductProtein amountFat contentPriceCost per servingNumber of servingsCustomer reviews
Primegenix25 g0 g$79.95$2.66
304 stars
Transparent Labs28 g1 g$59.99$2304.5 stars
Kaged Protein25 g0 g$39.99$1.60254.8 stars
Onnit20 g2 g$59.95$2304.3 stars
23 g1 g$54.95$1.83304.8 stars

How high cholesterol impact your health?

Cholesterol is a fat-like substance found in the blood and cells of the body. Your body needs cholesterol to function; however, when you have too much, it can start building up in the walls of your arteries and constrict blood flow, a condition known as atherosclerosis.

High cholesterol can be caused by lifestyle factors, such as eating a diet high in saturated fats, having certain medical conditions, not getting enough exercise, or having a genetic predisposition for high cholesterol.

You may be unaware that you have high cholesterol, as it does not cause symptoms. Most people discover they have high cholesterol through blood tests. Medical experts refer to high cholesterol as hyperlipidemia.

Without treatment, high cholesterol can cause serious health conditions such as:

Role of whey protein in cholesterol management

Whey protein is emerging as a possible tool for cholesterol management. However, research is in the early stages and has its limitations.

Here is what we currently understand about the role of whey protein in managing cholesterol.

Mechanism of action

While the exact mechanism of how whey protein helps lower cholesterol levels is still being researched, studies suggest that supplementing with whey protein can help lower cholesterol levels and reduce cholesterol build-up in the arteries.

One possibility is eating a diet rich in protein can help you feel full for longer, which may reduce the urge to snack throughout the day. Thus, possibly cutting down on other foods with saturated fats, which are a major source of cholesterol.

Whey protein is also considered a lean protein that does not contain saturated fats. Many other sources of protein do contains saturated fats. Consuming whey protein, which contain no saturated fats, may have a positive effect on cholesterol levels.

Potential impact on lipid profile

Your body has two types of cholesterol that medical providers monitor.

Low-density lipoprotein (LDL) cholesterol, also known as “bad cholesterol,” makes up the majority of your body’s cholesterol. Having high levels of LDL increases your risk of stroke and heart disease.

High-density lipoprotein (HDL) cholesterol, referred to as “good cholesterol,” helps carry cholesterol back to the liver, where the body can flush it out. Having higher levels of HDL can lower your risk for stroke and heart disease.

Multiple studies suggest that supplementing with whey protein helps to lower LDL levels and may increase HDL levels.

Research evidence supporting protein's efficiency

While we look forward to more research on this topic in the future, here is what some current studies show us.

A 2018 study on mice with a predisposition to high cholesterol found that the mice supplemented with whey protein had lower cholesterol levels, decreased plaque build-up in the arteries, and higher levels of HDL cholesterol (the “good cholesterol”).

A review of research literature in 2020 revealed that studies on supplementing with whey protein show significant reductions in total cholesterol and LDL-cholesterol. However, there is not much evidence that whey protein affects HDL-cholesterol levels.

Other health benefits of protein

Protein is the building block for many tissues, including muscles, bones, skin, cartilage, and blood. Getting enough protein in your diet is essential for overall health and well-being.

Muscle growth and repair

When you participate in physical activity, particularly strength training, your muscles experience micro-tears in their fibers. Protein helps heal your muscles and promote growth and increased strength over time.

Consuming a rich-protein diet helps ensure your body has the necessary nutrients to effectively repair and strengthen your muscles, contributing to overall better muscle health.

Weight management

Another benefit of consuming protein is its role in healthy weight management. Including protein in your meals and snacks helps you feel full for longer, which can cut down on eating extra calories.

A 2020 review of scientific literature suggests that eating a diet high in protein also increases your metabolism, which plays a role in weight management. However, during times of weight loss, eating enough protein will also help maintain lean muscle mass.

Overall health and immunity

Protein is essential for the maintenance and function of several body systems. It is involved in making hormones, enzymes, and vitamins. The immune system relies on protein to make antibodies, which are essential for fighting off sickness and infection.

The USDA My Plate recommends eating a variety of protein throughout the day to help you meet your nutritional needs. Along with whey protein, focus on eating other protein-rich foods such as:

Tips for maximizing the cholesterol-lowering benefits of whey protein

To get the most cholesterol-lowering benefits out of your whey protein, it’s best to integrate it into your daily routines.

Start by choosing a high-quality whey protein from a company you trust and a flavor and consistency you enjoy. Here are several ways you can incorporate whey protein into your day.

  • To kickstart your metabolism, include whey protein in your breakfast by adding it to smoothies, pancake batter, yogurt, or oatmeal.
  • For a snack, premake some protein balls, mix in a batch of muffins with whey protein powder, or add some whey protein to yogurt.
  • If you need an afternoon pick-me-up, try frothing or blending your coffee with your whey protein to make a delicious beverage.
  • When short on time, simply shake some whey protein in a shaker cup with your favorite beverage.

Potential side effects and precautions of using whey protein

Whey protein is generally considered safe when consumed in moderation and according to serving suggestions.

If you have a sensitivity or intolerance to lactose or milk it’s a good idea to look for an alternative type of protein because whey is derived from milk. Consuming whey protein may cause digestive symptoms similar to when you consume milk.

A 2021 review of scientific literature, found that excessive intake of whey protein over a long period of time can cause damage to the kidneys or liver.

If you are considering adding whey protein to your diet and have questions about what amount is right for you, consider talking with your primary medical provider or consulting a registered dietitian for personalized guidance.

Best whey protein to lower cholesterol — conclusion

Lowering cholesterol levels often takes a multifaceted approach, including diet and lifestyle factors. Your medical provider may also suggest medications to lower cholesterol.

Whey protein is a great supplement to add to your diet if you are looking to lower cholesterol. This low-fat lean protein is derived from milk and is considered a complete protein as it contains all nine essential amino acids.

Increasing your intake of whey protein may help you feel more full and decrease your consumption of other foods that may contribute to high cholesterol levels.

When looking for a whey protein, do some research on the quality of the ingredients, the reputation of the brand, and other factors that relate to your individual dietary needs.

Talk with a medical provider about how much whey protein you should include in your diet each day and what other types of foods and lifestyle changes can help in your journey to decrease cholesterol.

Getting your cholesterol in a healthy range can help enhance your overall well-being, heart health, and lower your risk for heart attack and stroke.

Further reading

Learn which protein powders we chose as the best tasting protein powders.

Discover our top protein powder picks for women’s health.

Explore our top choices for protein powders for health and fitness.


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