Grains of Paradise: The Surprising Health Benefits

Grains of paradise, scientifically known as Aframomum melegueta, are actually not grains at all. They are small, reddish-brown seeds that resemble grains and are commonly ground into a spice used in cooking (similar to peppercorns being ground into pepper). Despite their long history of both culinary and medicinal use, it’s important to examine contemporary scientific findings around the health implications of grains of paradise. In this article, we’ll delve into the latest research to uncover potential health benefits associated with these multifaceted seeds.

Origin and historical use

Grains of paradise are the seeds of a plant in the ginger family (Zingiberaceae). They have been utilized for generations in West Africa, particularly Liberia, Nigeria, and Ghana. Their distinct flavor, a mixture of pepper, cardamom, and ginger, made them a sought-after spice for dishes like soups, stews, meat marinades, and to make spicy sauces.


Over time, grains of paradise used in food evolved into traditional healers using them for their purported medicinal properties. These seeds were often brewed in teas or decoctions to address health issues like digestive disorders, immune problems, and joint pain. Although the seeds are used most often, the leaves, roots, and stems have also been used in traditional medicine to potentially support well-being.

Nutritional profile

Grains of paradise boasts a rich nutritional profile. Also, these seeds contain bioactive compounds, like flavonoids, alkaloids, phenolic compounds, tannins, cardiac glycosides, terpenoids, and saponins. It’s believed that these compounds are what give grains of paradise their potential medicinal properties. While there's ongoing research into its exact nutritional composition, it's believed to contain biologically active compounds, phytochemicals, and antioxidants that potentially offer various health benefits.

Health benefits

There are a multitude of health benefits that grains of paradise are said to potentially have. While research is ongoing, several studies suggest these seeds may offer various health advantages for overall well-being. Keep reading to learn some of these potential health benefits.

Grains of paradise and digestive health

Grains of paradise have shown promise in supporting digestive health. A study on rodents suggests that the active compound — gingerol — found in high amounts in grains of paradise, acts on the gut epithelium, regulating intestinal contractions. Regulating the smooth muscle movements of the GI tract may potentially help lower the incidence of indigestion, flatulence, bloating, and irregular bowel movements (especially diarrhea and upset stomach).

Metabolic effects


One of the notable properties of grains of paradise is their thermogenic effect, which may contribute to improvements in metabolism. Limited studies indicate that they can increase energy expenditure and fat oxidation, potentially supporting weight loss.

A double-blind placebo study in the Journal of Drug Design, Development and Therapy examined the effects of an herbal extract of grains of paradise on visceral fat (fat around your organs) and energy expenditure (i.e., metabolism). Sixty overweight men and women were studied over 12 weeks. One group was given 250 mg of grains of paradise extract twice a day, and the other group was a placebo with no biologically active compounds.

After 12 weeks, the grains of paradise group had an 18.55% increase in energy expenditure compared to the placebo group. The study also noted the mean change in fat mass was higher in the grains of paradise extract group. They attributed these effects to the 6-paradol compound found in them.

Although the results of this study are promising, further research is needed to fully define their mechanisms and effectiveness in regard to metabolism and weight loss.

Anti-inflammatory effects

Grains of paradise exhibit anti-inflammatory properties attributed to their bioactive compounds, specifically gingerol, paradol, shogoals, phenols, and flavonoids. These compounds might help mitigate inflammation in the body via multiple pathways.

Lowering inflammatory pathways and increasing inflammation-fighting genes could potentially help lower the risk of chronic diseases associated with inflammation. Comparative studies have shown promising results, although more long-term research is needed to confirm their efficacy.

Grains of paradise and cardiovascular health

Preliminary studies suggest that grains of paradise may have beneficial effects on cardiovascular health due to their high levels of the compound dihydroparadol. The seeds have been associated with lower blood pressure and heart rate, as well as improvements in cholesterol levels, all of which can be potentially cardioprotective.

One research study explored the effects of grains of paradise seeds on blood pressure. The study found that 10–20 seeds per day lowered blood pressure in both normotensive (normal blood pressure) and hypertensive (high blood pressure) participants. Furthermore, both systolic and diastolic pressures showed significant reductions.

Taking this into account, people with hypo/hypertension or on medication should be cautious when considering grains of paradise and consult their doctor regarding further steps.


The study suggested these effects could potentially reduce the risk of heart disease, heart attack, and stroke. Although these are very promising findings, further clinical trials are needed to understand the exact mechanism of action grains of paradise have on the cardiovascular system.

Antioxidant properties

Grains of paradise possess antioxidant properties, mainly from their high flavonoid concentration. Flavonoids like quercetin are well known for their high antioxidant activity.

Antioxidants play a crucial role in combating free radicals in the body. Free radicals are unstable molecules that cause oxidative stress or damage to otherwise healthy tissues. Antioxidants help stabilize these unstable molecules, neutralizing them and preventing them from causing further damage in the body.

The Annals of Microbiology and Infectious Diseases published a report on grains of paradise examining all of their potential health properties. They highlighted the high flavonoid content of the seeds and discussed the potential anti-carcinogenic and anti-mutagenic properties of these flavonoids and how they may address carcinogenic activity (or cancer-causing activity). These benefits are promising, and research institutions are eager to keep exploring how and why they work the way they do.

Pain relief and analgesic properties

The high gingerol content of grains of paradise is believed to have analgesic properties, potentially helping to alleviate pain and discomfort. It is still unclear if this analgesic (or pain relief) effect is direct from the gingerol itself or if it is because of the strong anti-inflammatory properties of many of the compounds in the seeds. While their application in traditional medicine for pain relief is well-documented, more research is needed to be certain of their efficacy and exact mechanisms of action.

Impact on blood sugar and diabetes management

Grains of paradise have demonstrated potential antidiabetic effects. The high content of 6-paradol, 6-shogaol, 6-gingerol, and oleanolic acid compounds inhibit enzymes responsible for breaking down carbohydrates and polysaccharides into simple sugars that increase blood sugar levels. These effects could be beneficial for individuals with diabetes or those at risk of developing the condition. However, further clinical studies are necessary to validate their efficacy and safety in this context.

Antimicrobial activity and immune system support


The phytochemicals (or plant chemicals) in grains of paradise, such as saponins, sterols, flavonoids, tannins, terpenoids, and alkaloids, all have antimicrobial properties. By fighting off bad bacteria, these phytochemicals can act as immune protectors, potentially preventing infection and supporting immune health.

A study conducted by the International Journal of Biology found that the seed extract of grains of paradise inhibited bacterial growth in Shigella spp, E. Coli, Klebsiella spp, and Salmonella spp, with the highest antimicrobial activity being against E. Coli, Klebsiella, and Salmonella.

In addition to antimicrobial properties, the study also suggested these compounds may have an immunomodulatory action, helping stimulate the immune system to protect itself, fight inflammation, and fight infection. Grains of paradise's antimicrobial and immunomodulatory effects hold promise, but more rigorous studies are needed to confirm their efficacy and mechanisms of action.

Enhancement of sexual health and libido

Grains of paradise have a longstanding reputation as an aphrodisiac both in traditional medicine and contemporary usage. Scientific studies have explored their effects on sexual health and libido, with some studies indicating positive outcomes, but these studies are primarily animal studies. These animal studies did find greater sexual arousal, sexual performance, and penile erection in rats; however, human studies have yet to be performed to know for sure.

Consumption, safety, and dosage

When consuming grains of paradise, it’s important to start with small amounts, especially if you're not accustomed to the strong flavor and potency. The seeds can be ground and used as a spice in cooking meats, soups, and stews, or they can be added to beverages like tea or smoothies. Experiment with different applications to discover your favorite ways to enjoy the unique taste.

While generally regarded as safe for most individuals when consumed in culinary amounts, it's advisable to exercise caution with grains of paradise supplements due to the lack of standardized dosages (there is no current safe RDA) and potential interactions with certain medications. Consultation with a healthcare professional is recommended, especially for those with underlying health conditions or on medication.

Comparison with other health-boosting spices

Grains of paradise offer a unique flavor profile and potential health benefits similar to some other spices you may be familiar with, such as:

  • Black pepper. Both have similar culinary uses, flavors.
  • Turmeric. Both have strong anti-inflammatory properties.
  • Ginger. They come from the same family, similar compound profiles, with anti-inflammatory properties.
  • Cayenne. Both spices have thermogenic properties, potentially helping with metabolism.

While these spices share some similarities, grains of paradise are distinct in their unique combination of all of these potentially beneficial compounds and properties.

Purchase and storages

When purchasing grains of paradise, opt for reputable sources that offer high-quality, organic products. Store them in an airtight container away from heat and sunlight to preserve their flavor and potency for as long as possible.

Grains of paradise stand out in both their culinary applications and their potential health-promoting properties. From digestive support to metabolic health and beyond, these versatile seeds offer a myriad of potential health benefits backed by limited scientific research and centuries of traditional use. Incorporating grains of paradise into your diet can be a flavorful and nutritious way to enhance overall well-being.


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