If you purchase via links on our site, we may receive commissions. However, our experts carefully research and evaluate each product or service, ensuring it meets our quality standards.

Bonafide Relizen: Does This Menopause Supplement Really Work?

Menopause can be an incredibly challenging phase in a woman's life, impacting her both physically and mentally.

Hot flashes are, by far, the most common symptom of menopause that may vary in frequency and intensity for each woman. About 75% of all women have these sudden, brief, periodic feeling of increased body temperature.

Symptoms such as mood swings, sleep disturbances, vaginal dryness, and worsened hair and skin health can also persist for years, causing significant distress. For this reason, many seek holistic approaches to hormone-free relief.

Therefore, in this review, we explore one such option: Bonafide’s hormone-free supplement, Relizen. Specifically designed to help alleviate menopausal hot flashes and night sweats, which are among the most disruptive vasomotor symptoms.

We will touch on scientific evidence of the supplement’s proposed effectiveness, evaluate reviews online, and highlight the potential benefits as well as drawbacks.

Get 34% OFF a 3-month plan!
Bonafide Relizen

What is Relizen?

Relizen is a non-hormonal dietary supplement that comes in the form of tablets and is specifically designed for hot flashes and night sweats.

The main ingredient is derived from the pollen of multiple Swedish flowers, which has been studied for its potential effects on helping balance hormones and regulate temperature in menopause.

Relizen is often marketed as a natural alternative to hormone replacement therapy (HRT) and is popular among women seeking non-hormonal solutions to manage menopause-related symptoms.

Is Relizen all-natural?

Purified cytoplasmic blend which is proprietary Swedish flower pollen extract (Sérélys) is a natural ingredient that is predominant in Relizen supplement.

However, other ingredients may be semi-synthetic or synthetic, and the origin of these additional ingredients is unknown.

Pros and cons of Relizen

Why did we choose to review this product?

We reviewed Relizen to give women accurate and unbiased information, helping them decide if it can potentially address hot flashes and night sweats.

This is the criteria based on which we evaluated Relizen:

  • We conducted a thorough check of the manufacturer's claims.
  • Evaluated if the brand is transparent and has certifications, conducts third-party testing, is cGMP compliant, and more.
  • Examined if the ingredient list is evidence-backed for suggested purposes.
  • Analyzed scientific research to evaluate Relizen’s potential efficacy.
  • Looked into customer feedback and satisfaction rate.

Relizen: a quick overview

Relizen is part of the health and wellness brand Bonafide Health LLC, established in March 2017. The brand specializes in manufacturing natural, hormone-free solutions for women going through menopause, dedicating its production to addressing common symptoms such as vaginal dryness, sexual satisfaction, hot flashes, night sweats, and hormonal imbalances.

Based on the brand claims, Bonafide supplements meet the highest standards of safety and efficacy, and they are evaluated through clinical testing using double-blind, placebo-controlled trial design.

In addition, Bonafide claims to source ingredients from carefully vetted suppliers committed to quality and production safety. The supplements are manufactured in GMP-compliant facilities in the U.S. and Italy, where they undergo regular quality inspections.

The company complies with all government-required regulations and has obtained additional certifications:

On the contrary, the company lacks accreditation from the Better Business Bureau (BBB)*, though it holds an A-rating due to its responsiveness to customer complaints, addressing issues, and maintaining transparency in its business operations.

Based on BBB claims, they contacted Bonafide in March 2023 and asked for evidence for claims. Bonafide claims include “safe and hormone-free,” “scientifically validated,” “recommended by over 8,300 doctors,” and “7 out of 10 experience symptom relief in 2 months or less,” which, according to BBB, breach the advertising code of conduct. As of now, Bonafide has not responded to the BBB or modified its advertising statements.

Moreover, the brand claims that each batch is tested by a third party, and the results are published with Certificates of Analysis (COA).

However, despite our search, we were unable to find Certificates of Analysis available to the public on the official Bonafide website.

*BBB — The Better Business Bureau (BBB) is a private organization that offers information about businesses and charities to the public. It also manages consumer complaints related to businesses.

Relizen's ingredients

This Bonafide supplement is mainly made from purified cytoplasmic blend which is a proprietary Swedish flower pollen extract (Sérélys). The tablets also contain ingredients playing a role in supplements’ stability and delivery format. Find a detailed ingredient list below.

These additional ingredients included in this formulation might be used to improve shelf life, support active ingredient’s stability, and enhance user experience. However, they don’t play a major part in the supplement effects as the main ingredient Sérélys®.

Bonafide Relizen Supplement Facts
Via hellobonafide.com website

Relizen's safety and effectiveness

How effective is Relizen?

We found some scientific evidence demonstrating possible Relizen's effectiveness in reducing hot flashes and night sweats, although individual results may vary.

In 2008, one study found that Sérélys® (Femal®), a natural product containing pollen cytoplasmic extracts, might be effective in reducing menopausal hot flashes and night sweats. Involving 417 women with menopause, the trial demonstrated significant improvements in these symptoms, as well as overall quality of life, as assessed by a questionnaire. Additionally, Sérélys® was well-tolerated, with most participants experiencing excellent or good tolerance.

A 2019 review article has reported that PureCyTonin®, a purified and specific cytoplasmic pollen extract, might be a safe and non-estrogenic alternative for managing certain symptoms of menopause. It has been evaluated in several preclinical and clinical studies, demonstrating beneficial effects in hot flash relief and even premenstrual syndrome symptoms.

Lastly, a 2020 observational study comparing soy isoflavones with pollen extracts found that non-hormonal treatments with pollen extracts may effectively alleviate menopausal symptoms and sleep disturbances. After six months, women using pollen extracts showed a greater reduction in daily hot flash incidence, improvement in menopause-related symptoms, and enhanced sleep quality compared to those using soy isoflavones*.

*Soy isoflavones are naturally occurring compounds found in soybeans and other soy products. They are phytoestrogens, which have a chemical structure similar to estrogen, the female hormone. Because of this similarity, soy isoflavones are believed to interact with estrogen receptors in the body and may exert weak estrogenic effects.

Are there side effects with Relizen?

Some people may experience possible gastrointestinal side effects, including nausea, vomiting, diarrhea, constipation, and flatulence.

In one clinical trial, 0.72% of women experienced side effects such as migraines and allergic-type rhinitis, which resolved once treatment was discontinued.

Additionally, Relizen may not be suitable for individuals with pollen allergies.

How long does it take for Relizen to work?

According to the brand, Relizen is designed to provide relief gradually over time. A 2019 clinical study reported that most women experienced noticeable reductions in the frequency and intensity of hot flashes and night sweats by the third month of consistent use. Survey data further suggests that the benefits of Relizen tend to increase with prolonged use.

How to use Relizen?

For optimal results, it is recommended to take Relizen daily for at least three months. This extended period may allow the body to fully adjust to the supplement's effects, potentially contributing to its effects in reducing menopausal hot flashes.

Is Relizen safe to take long-term?

There is insufficient data to confirm Relizen's long-term safety. Clinical studies have examined its effects for up to three months, but further research is necessary to assess its safety over extended periods.

What is the best time of the day to take Relizen?

The brand recommends taking two tablets of Relizen daily. However, on the official Bonafide website, there is no specific guidance regarding the best time of day to take the supplement or whether it should be taken with food, leaving the decision-making up to the customer.

We advise you to consult your doctor for personalized advice regarding the timing and dosage adjustment.

How much does Relizen cost, and where can I buy it?

Relizen is priced at $58 for a one-time purchase and will cost you approximately $1.23 per single serving, depending on purchase type.

Alternatively, you can opt for a subscription model to save on costs. The monthly subscription plan costs $42 per month, offering a 28% discount. If you choose the three-month subscription plan, you pay $114 quarterly, which breaks down to $38 per month, providing a 34% discount.

It is important to note that shipping is calculated at checkout, and free shipping only applies to subscription orders.

Lastly, you can purchase Relizen directly from the official Bonafide website or from the Bonafide Amazon page.

What users are saying?

Relizen has numerous reviews on Reddit, YouTube, and Amazon. However, it is important to note that customer feedback is only subjective.

BBB rating — 1.14 ⭐

Amazon rating — 4.0 ⭐⭐⭐⭐

Trustpilot rating — not available

Rating on Bonafide website — not available

What do people like about Relizen?

After going through hundreds of Relizen reviews, we found that customers on Amazon and YouTube appreciated the supplement immensely. They claimed it effectively eliminated hot flashes, reduced their frequency, and prevented night sweats.

One woman in particular noted she used to experience hot flashes every other hour and after a few weeks of use her hot flashes got reduced to a couple of hot flashes a day for a week. She also noticed that the intensity of hot flashes dropped from highly intense to mild, and they went “away pretty quickly.”

What people didn't like about Relizen?

On the other hand, opinions about Relizen vary regarding its value for money and effectiveness. Some people found it expensive and not worth the cost and others have mixed feelings about Relizen's overall performance, stating they have not experienced any changes or improvements in their well-being.

Additionally, customers on the Better Business Bureau® (BBB) website are expressing frustration with Bonafide subscription and customer service practices. They criticize the lack of clarity on canceling subscriptions and the absence of notifications before shipments, leading to unwanted charges.

Comparing Relizen with other similar supplements

Here, we are going to compare Relizen with other competitor-brand supplements. Relizen distinguishes itself from other products because it is the only supplement with an active ingredient that has undergone rigorous clinical testing, including double-blind, placebo-controlled trials. Although it is the priciest option compared to its competitors, it remains the most researched, certified, and transparent product.

ProductPriceHormone-freeDesigned forClinically studied ingredientsForm
Bonafide Relizen®$58.00YesPotential relief from menopausal hot flashes and night sweatYesTablet
NuviaLab® Meno $39.99YesPotential relief from menopausal hot flashes, irritability relief, and enhancement of quality of sleepYesCapsule
Ora$34.99YesPotential hormonal balance support, irregular periods, hot flashes, and fatigueN/ACapsule
Aura Essentials$29.99YesPotentially alleviates menopausal hot flashes and night sweatsN/AGummies
Estroven® $19.99YesPotential hot flashes, night sweats, hormone-related irritability reliefYesTablet

Other natural ways to help with menopause symptoms


If you are still not sure about trying natural supplements like Relizen and whether they can help you relieve common menopause symptoms, there are other natural ways to potentially help better your situation. Fortunately, dietary supplements are not the only natural option.

To help ease the transition through menopause, many women noticed that exercise, proper nutrition, and a good night's sleep can help alleviate symptoms and reduce hot flashes.

For example, some evidence indicates that following a Mediterranean-style diet might alleviate certain short-term symptoms of menopause, such as vasomotor symptoms, which include hot flashes (sudden sensations of heat or cold in the face, neck, and chest) and night sweats.

According to the British Nutrition Foundation, avoiding alcohol and caffeine can also be useful, as caffeine might increase irritability and alcohol consumption is known to trigger menopause symptoms.

Final thoughts: does Relizen really work?

In conclusion, Relizen may offer potential benefits for women seeking natural relief from menopause symptoms, such as reductions in hot flashes and night sweats and reported improvements in mood and well-being.

However, individual responses can vary, and some users may experience mild side effects.

Therefore, it is important to consult your healthcare provider before considering Relizen. The doctor can advise whether Relizen is appropriate for your specific health needs and discuss potential interactions with medications or other treatments.

Get 34% OFF a 3-month plan!
Bonafide Relizen


Leave a reply

Your email will not be published. All fields are required.