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Bonafide Serenol Reviews: Does This PMS Supplement Work?

Many people assigned female at birth who have reached puberty suffer from premenstrual syndrome (PMS), with symptoms such as mood swings, irritability, bloating, cramps, and food cravings, to name a few. PMS usually occurs a few weeks before one's period and is believed to be caused by natural hormone fluctuations. The reason why some experience severe symptoms while others barely have any is not fully understood.

Unfortunately, there are not many natural, high-quality supplements available on the market to help address such concerns.

Serenol by Bonafide may seem like that product exactly: hormone-free, made of natural ingredients, and formulated to help with PMS. It sounds like a miracle, but does it work?

We reviewed Serenol to provide an unbiased and comprehensive opinion, addressing its potential effectiveness, ingredients, and possible side effects based on the ingredient list and user experiences to help you determine if it’s the right option for you.

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Bonafide Serenol

What is Serenol?

Serenol is a non-hormonal dietary supplement that has been designed to help alleviate physical and emotional symptoms that occur before menstruation.

The formula is scientifically evaluated and includes a blend of vitamins, minerals, and plant extracts aimed to provide benefits for the whole body.

Serenol is popular amongst individuals looking for a natural way to help relieve PMS symptoms, such as bloating, unstable moods, and cravings, without the need to resort to hormonal treatments.

Serenol: a quick overview

PricePrimary ingredients Allergy informationTargeted symptomsServing sizeBrand review
$63 for 1 month's supply ($2.10 per serving)Chromium picolinate, purified cytoplasmic blend (proprietary Swedish flower pollen extract (Sérélys) in the form of pollen + pistil extract PI-82, and pollen extract GC-FEM), royal jellyNot suitable for people with bee or pollen allergiesMood swings, bloating, curb cravings2 tablets once a dayBonafide


  • Researched. Bonafide conducted an online survey in which participants reported an observed reduced irritability, mood swings, and emotional discomfort associated with PMS. Royal jelly has been shown to reduce PMC symptoms among students. Meanwhile, Sérélys has been shown to reduce irritability, headaches, and water retention after a consistent four-month administration in women with PMS.
  • Non-hormonal. Serenol is a hormone-free supplement that may offer natural PMS relief.
  • Natural ingredients. Serenol aims to manage symptoms associated with PMS by using natural ingredients rooted in traditional medicine.
  • Positive reviews. Many users report experiencing significant PMS symptom relief when using the product.


  • Variable effectiveness. Serenol's results may be highly individual and influenced by factors such as age, health status, severity of symptoms, and lifestyle, among others.
  • Symptom specificity. Serenol is not formulated to address all symptoms and may, thus, be less effective for women who experience different issues.
  • Potential side effect. In rare cases, users report experiencing gastrointestinal discomfort when using the product.
  • Not suitable for people with bee and pollen allergies. Ingredients make Serenol unsuitable for people with bee and pollen allergies.
  • Requires consistent use. According to Bonafide's research, at least two months of consistent use is required to see benefits. This might be daunting for women seeking immediate relief.

How and why we chose to review this product

Our mission is to empower people assigned female at birth by providing unbiased product reviews and disseminating the science behind female health. The high prevalence of PMS symptoms and Serenol's growing popularity prompted us to conduct a thorough review.

To ensure a well-rounded assessment, we examined reports of clinical trials, user feedback, Bonafide's official claims, and Serenol's ingredients. Our goal is to educate our readers, helping them make informed decisions about their health and whether Serenol is a product that may assist in managing and reducing symptoms of PMS.

How much does Serenol cost, and where can you buy it?

You can buy Serenol on the official Bonafide website. A one-time purchase of a month's supply costs $63, but it goes down to $48 per month if you subscribe. If you purchase a three-month supply, it costs $129 quarterly, which works out to $43 per month.

Serenol can also be purchased on Amazon, Walmart, and other major retailers.

Serenol's effectiveness and safety

Quality, effectiveness, and safety are crucial when choosing supplements. Hence, we look at some of the most common questions and concerns below.

What are the potential benefits of Serenol?

Serenol is formulated to alleviate PMS and is proposed to contribute to reduced irritability, mood swings, and other emotional PMS symptoms. Its ingredients, such as Sérélys, royal jelly, and chromium picolinate, may work synergistically to help balance mood swings and curb cravings.

According to an online survey conducted by Bonafide, Serenol is a popular non-hormonal PMS relief aid. Customers report significant improvements with consistent use.

Does Serenol help with anxiety?

Although Serenol is not formulated to help reduce anxiety, it may offer some anxiolytic effects by helping promote a more stable mood and reducing emotional PMS symptoms. As anxiety at the end of a menstrual cycle can be a sign of premenstrual syndrome, Serenol's potential effects on emotional symptoms may contribute to some relief.

Does Serenol help with weight loss?

Serenol is not a weight loss supplement. However, it is promoted to help curb cravings, which may result in lower calorie intake and potentially support weight maintenance.

Does Serenol have side effects?

Serenol is generally well tolerated; however, some users may experience gastrointestinal side effects.

People with bee and pollen allergies should not use Serenol, as the inclusion of royal jelly can trigger an allergic reaction. If you suspect side effects of Serenol, you should stop using the product and consult a healthcare professional.

Who should not take Serenol?

Serenol is not suitable for people allergic to any of the ingredients. Individuals with underlying health conditions, pregnant, breastfeeding, or taking prescription medication should consult their doctor before using the supplement.

Is Serenol FDA approved?

Supplements are not regulated or approved by the FDA. However, Serenol is manufactured in accordance with stringent quality standards and is third-party tested for label accuracy.

Serenol's ingredients and usage

Sérélys®, a blend of Swedish flower pollen extracts, is the star ingredient in Serenol. It has been suggested that it can reduce emotional PMS symptoms. The participants of one study also reported a reduction in water retention and headaches with consistent use.

Royal jelly is a bee-produced substance that has been used as a functional food in traditional medicine due to its high nutrient content. It is rich in vitamins and minerals, which may contribute to the proposed royal jelly's antioxidant, anti-inflammatory, and anticancer properties. A study has found that royal jelly improved glucose metabolism and mental health in humans when consumed consistently for six months. By contributing to improved overall well-being and mood, royal jelly may be able to help reduce PMS symptoms, especially irritability and mood swings. Royal jelly is also suggested to promote longevity and ease menopausal symptoms, as it promotes longevity and fertility in honeybees; however, there are no supporting human studies.

Chromium picolinate is an essential mineral that has been reported to decrease carbohydrates and food cravings. This may be useful for reducing PMS-induced cravings; however, most studies have been done in rats and at higher doses. In a small self-reported study, chromium was also associated with reduced emotional symptoms and improved overall health.

Bonafide recommends taking two tablets of Serenol daily, preferably with food, for better absorption. According to the manufacturer, consistent use for at least two months is needed to start seeing benefits. However, most users report seeing significant results after three months of consistent use.

As it is with all supplements, before starting the use of Serenol, it is best to consult a healthcare professional. Keep in mind that while it may help with some PMS-induced symptoms such as anxiety, irritability, and craving, Serenol is not designed to treat anxiety disorders or promote weight loss

What users are saying

Amazon rating — 4.3 ⭐⭐⭐⭐

Rating on Bonafide's website — unavailable

Numerous Serenol reviews are available on the internet, including Amazon, Reddit, and blogs, with users sharing their experiences. We have summarized the customer feedback for your convenience so you can get a wider picture.

What people liked

Many customers report seeing significant improvement in mood swings, irritability, and bloating. Users like that Serenol offers a natural, hormone-free way to ease their symptoms. Some users also report feeling an overall improvement in mood, energy levels, and well-being. There are a few customers reporting such effective curb of their PMS that they only know their period is coming based on the calendar and not symptoms.

What people didn't like

Some customers report not seeing any effects even with consistent use. A few also reported experiencing cramps and stomach aches when using the product. A few users also felt that the price was too high.

Serenol vs. other PMS remedies

Multiple products offer similar benefits as Serenol. We have reviewed and compared the best non-hormonal PMS remedies.

ProductPriceServingStar ingredientsMarketed forBrand review
Bonafide Serenol $63 ($2.1 per serving)2 tabletsSérélys, royal jelly, chromium picolinateReducing mood swings, irritability, and food cravingsBonafide
Aura Essentials PMS Gummy$19.99 ($0.67 per serving)2 gummiesMaritime pine bark, dandelion root, chasteberryMood, energy, and hormone balance, reducing cramps and hormonal acneN/A
Ora Harmonius$34.99 ($1.16 per serving)1–2 capsulesOrganic acerola extract, organic burdock, organic gelatinized maca, organic ashwagandha, organic cordyceps, organic holy basilAcne relief, increasing energy, reducing mood swings, hot flashes, and stressN/A
Femometer Evening Primrose Oil$16.99 ($0.28 per serving)1 softgelEvening primrose oil, omega-6 fatty acidReducing PMS-induced irritability, bloating, and acne, supporting hormone balance, and promoting skin elasticityFemometer
Aspen Green Relief CBD Oil$149.99 ($5.00 per serving)1 mlFull-spectrum hemp extract, hemp terpenes, MCT oil, turmeric extract, ginger extract, chamomile extract, black cumin seed extract, rosemary extract, and black pepper essential oilReducing PMS-induced stress and anxiety, promoting relaxation. May also reduce crampsAspen Green

Final verdict: is Serenol right for you?

Serenol is a promising natural and hormone-free product formulated to provide PMS symptom relief. It may help with symptoms such as mood swings, irritability, bloating, and cravings. The star ingredients, Sérélys, royal jelly, and chromium picolinate, may offer many benefits in theory; however, there is a lack of human research. The ingredients have also not been clinically tested as a combination.

A survey done by Bonafide and numerous positive reviews suggest that Serenol may reduce PMS symptoms with consistent use. However, it is important to keep in mind that this supplement will not solve any major underlying issues and may only provide a little bit of relief. It is crucial to look at your overall lifestyle and health status.

The product may not be suitable for people with bee allergies, or sensitivities to any of its ingredients. Individuals with serious medical conditions or on prescription medication should consult their doctor before introducing a new supplement.

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Bonafide Serenol


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