Which Injections Can Help Lose Weight?

Weight loss injections have been increasing in popularity in recent years. This article explores how well these fat-burning injections work and compares some of the most popular options.

In this article, we’ll cover some of the most popular fat loss injections, including weight loss injections in the stomach, plus some safety concerns, risks, and tips for losing weight in a healthy way.

Are weight loss injections safe?

Weight loss injections can sound appealing. However, it’s important to note these injections are not for everybody and some injections can have side effects.

Some of the most popular injections for weight loss have not been approved by the FDA. Others have very little research on the long-term effects. Even the injections that are approved for weight loss can have side effects, ranging from gastrointestinal discomfort to severe and long-term health concerns.

Talk to your doctor to see if you're a candidate for weight loss injections.

Can you use diabetic injections for weight loss?

Diabetes medications like Saxenda, Ozempic, and Rybelsus can help type 2 diabetics manage blood sugar. Some users also find that it helps manage weight. However, many of these diabetes medications are not approved for weight loss. Saxenda is the only diabetes medication on this list approved by the FDA for weight loss.

Which weight loss injections are the best?

Let's have a deep look into all possible weight loss manipulations and their effectiveness.


Saxenda (liraglutide) is used for both diabetes management and for chronic weight management. Saxenda increases insulin production and lowers blood sugar levels. It also slows the rate your body digests food, which can help with appetite suppression.


Wegovy (semaglutide) is a weekly injectable weight loss medication. Wegovy is a GLP-1 drug that can help you lose weight by restricting your appetite.


Ozempic is a weekly semaglutide injection that can help control blood sugar levels, insulin, and appetite. However, Ozempic injections have a smaller dose (0.25–2 mg) than Wegovy. Ozempic has not been approved for weight loss.

Semaglutide (Rybelsus)

Rybelsus is a semaglutide medication that helps type 2 diabetes patients manage their blood sugar levels and suppresses their appetite. Unlike Ozempic and Wegovy, Rybelsus is a daily pill, not an injectable. It also has not been approved by the FDA for weight loss.


Human chorionic gonadotropin (HCG) is a hormone produced by the placenta during pregnancy. However, it is also sometimes marketed as an injectable or oral “supplement” for weight loss while paired with an extremely low-calorie diet.

Unfortunately, using HCG for weight loss can be dangerous. In fact, the FDA has warned people to stay away from HCG diet products. HCG supplements are also illegal; the only legal way to get them is through a prescription.


Vitamin B12, also known as cobalamin, is a water-soluble vitamin that plays a variety of roles in the formation of your red blood cells. It also is linked to your energy and metabolism, and some recent research suggests that vitamin B12 deficiencies may be linked to obesity.


Lipotropic injections are a mixture of vitamins and other nutrients thought to help people lose weight. They commonly include nutrients like vitamin B12, other B-complex vitamins, L-carnitine, or phentermine.

Advocates of lipotropic injections say these various ingredients can help with weight loss in several ways, like boosting your metabolism and energy levels. However, more research needs to be done to determine how effective these shots actually are for weight loss.


Peptides are synthetic substances that reportedly help with weight loss by mimicking the actions of your natural hormones. This can lead to a number of effects like increasing metabolic rate or subduing appetite. Some of the most popular peptides for weight loss include tesamorelin, CJC-1295, and ipamorelin. Semaglutide (like Rybelsus, Ozempic, and Wegovy) is also a peptide.

How long do weight loss injections take to work?

The time it takes for a weight loss injection to work can vary depending on the kind of medication you’re taking. It also depends heavily on the number of calories you are eating and burning in a day.

Tips on how to lose weight

Although the injections might seem like an easy way of weight loss, keep these tips in mind when pursuing the weight loss journey:

  • Don’t rely on injections alone for weight loss. They work best when paired with the right diet, exercise, and healthy lifestyle. It’s especially important to healthily manage weight since you may gain the weight back after you stop injections.
  • Focus on a calorie deficit. Being at a calorie deficit is the most important factor for losing weight. Be mindful of the portions you eat and incorporate regular exercise to increase calorie burn.
  • Consider your muscle mass. Rapid weight loss can sometimes lead to muscle loss. Make sure to include plenty of protein in your diet and add resistance training to your exercise regimen to maintain lean muscle.
  • Talk to your doctor first. While some of these weight loss injections may be helpful for weight loss, they can also have risks. Make sure to talk to a medical professional to make sure you’re losing weight safely.

Final word

While some injections on the list might help you lose weight, they can also come with long-term risks, so consider the consequences before injecting any. As with any injection or supplement, there can definitely be adverse side effects. If you’re trying to lose weight, talk with a medical professional before trying a weight loss injection to weigh the risks with the benefits that come alongside. Lastly, try to aim for certain lifestyle changes as well as incorporating a healthier diet into your everyday routine.


Key takeaways:

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