Bioma vs. Seed: Which Probiotic Is Best for Your Gut Health?

In the world of gut health, Bioma and Seed have emerged as some of the top probiotic brands for supporting a healthy gut microbiome.

Bioma takes a targeted approach and features three potent, scientifically-backed strains of Bifidobacterium bacteria and a prebiotic packed in delayed-release capsules. It is shelf-stable and vegan-friendly.

Seed embraces a more comprehensive strategy and boasts 24 diverse strains of bacteria encased in their innovative ViaCap® technology. The website lists studies supporting the use of each strain for gut health. The probiotic is also vegan-friendly and shelf-stable.

Whether you’re a health enthusiast aiming to improve your gut health or seeking relief from digestive trouble, our in-depth probiotic supplement comparison of Bioma and Seed will help you select the probiotic that’s right for you.

What is Bioma?

Bioma is a dietary supplement specifically designed to enhance gut health.

What makes it unique is its blend of three carefully selected Bifidobacterium strains, with some studies supporting beneficial effects on digestion. Each serving of two capsules offers nine billion colony-forming units (CFUs).

Bioma goes beyond a standard probiotic formulation and incorporates tributyrin, a type of fat that supports healthy intestines. However, research is limited, and only animal studies are available. It also contains xylooligosaccharides, which are prebiotics that help nourish healthy gut bacteria.

We love that this probiotic is blended in the U.S. and packaged in dark glass bottles to shield it from sunlight, which helps the probiotic stay more stable.

While Bioma doesn’t highlight specific certifications, awards, or partnerships, its commitment to quality is evident in its probiotic and prebiotic blend and thoughtful packaging.

What is Seed?

Seed Daily Synbiotic distinguishes itself with a probiotic formula of 24 scientifically studied strains of bacteria claimed to address digestive, skin, immune, and heart health.

The 2-in-1 nested capsules are engineered to survive harsh stomach acid, allowing the probiotic to enter the colon.

Each serving of two capsules contains 53.6 billion active fluorescent units (AFUs), which is considered a more precise count of viable cells than CFUs. It also contains a patented prebiotic, Microbiota-Accessible Polyphenolic Precursors (MAPP).

Seed is serious about quality. It performs testing at each step of the manufacturing process and claims third-party testing of the final product. The purity protocols meet both U.S. and European standards.

The brand also prioritized sustainability. Your first purchase arrives in a glass refillable glass jar along with a travel vial. Each month, you’ll receive a packet refill of your next 30-day supply.

Although Seed supplements have not yet received widely recognized certifications or awards, their commitment to research and transparency positions them as credible producers in the probiotic market.

Head-to-head comparison

Brand	Probiotic strains	Additional ingredients	Price	Subscription model	Packaging	Target audience	Unique features	Reviews
Bioma	B. lactis, B. longum, B. breve, 9 billion CFU	Tributyrin, Xylooligosaccharide	$25.99–69.99 per bottle, depending on the package	1 month supply, 3 month supply, 6 month supply	Dark glass bottle	Healthy digestion, weight loss support	Delayed release capsule, Synbiotic blend	Bioma review
Seed	24 strains, 53.6 billion AFU	Microbiota-Accessible Polyphenolic Precursors (MAPP)	$49.99 per 30-day supply	Monthly subscription-based	Sustainable, recyclable packaging, dark glass bottle	Overall gut health, digestive, heart, and skin health	ViaCap® delivery technology, 2-in-1 capsule	Seed review

Strain diversity and scientific backing

Seed showcases significantly greater bacterial strain diversity than Bioma, with 24 strains compared to Bioma’s three strains.

Both companies emphasize their use of clinically studied strains; however, the information provided varies.

Seed’s website provides detailed information on the studies backing its 24 strains. The company also provides information on two clinical trials being performed with the daily synbiotic.

One study looks at the effects of the probiotic on irritable bowel syndrome (IBS) and the other analyzes the effects of taking the daily synbiotic probiotic after a round of antibiotics.

Bioma’s website does not offer information on scientific research, but a review of clinical studies reveals that the Bifidobacterium strains benefit gut health.

Additional benefits

Both brands go beyond basic probiotic formulations by incorporating additional ingredients that enhance overall health.

Bioma includes tributyrin, a nutrient known to nourish colon cells, and xylooligosaccharides, a prebiotic fiber that promotes the growth of beneficial bacteria.

The manufacturer also claims the probiotic may help with weight management by enhancing the metabolism of fats and sugar. It’s important to note that weight management may occur when following a balanced diet and getting regular exercise.

Beyond gut health, Seed claims to offer additional benefits such as promoting healthy cholesterol levels and skin health, and supporting healthy gut immune function.

However, it’s important to note that it’s always best to consult your healthcare professional before using supplements to address specific health concerns.

Price and value

Bioma offers various bundle options and subscription discounts with prices ranging from $25.99 to $55.99 per bottle.

The Seed subscription is $49.99 per month, and you can save 10% by purchasing a three-month supply or 15% by purchasing a six-month supply.

The value of the probiotic depends on your individual needs and priorities. Bioma’s pricing options allow for more flexibility, while Seed's higher cost reflects its comprehensive approach and supporting research.

Side effects and safety

Probiotics are typically very safe to take. However, all supplements and probiotics have the potential to cause side effects. With probiotics, the most common side effects include:

• Nausea
• Gas
• Stomach discomfort
• Bloating
• Diarrhea
• Constipation

People under the age of 18, those who are immunocompromised, and people who are pregnant should talk with their healthcare professional before starting a probiotic.

How we evaluated Bioma and Seed

When evaluating Bioma vs Seed probiotics, we chose several criteria to compare them by.

These included scientific research, ingredients, probiotic strains, packaging, user reviews, and price.

• Scientific research. Seed had more information about scientific research on their website than Bioma.
• Ingredients. Bioma has the added benefit of tributyrin and xylooligosaccharide, which support digestive health in other ways than the probiotic strains.
• Probiotic strains. Seed has many more probiotic strains compared to Bioma. However, Bioma offers a more focused approach.
• Packaging. Seed comes with sustainable, recyclable packaging and doesn’t require a new bottle each month. Bioma comes in a recyclable glass bottle.
• User reviews. Bioma has a 3.6 out of 5-star review on Amazon, while Seed has an Amazon rating of 3.9 out of 5 stars.
• Price. Bioma offers several different prices depending on subscription and quantity, while Seed offers one option with a discount on subscription options.
• Third-party testing. Seed showcases manufacturing practices and third-party testing information on its website. Bioma does not provide this information.

Pros and cons

After our evaluation, we came up with our list of pros and cons for Bioma and Seed products.

Bioma

Seed

Best for…

This section provides a quick guide to help you determine whether Bioma or Seed aligns better with your individual needs and preferences.

Bioma

Bioma is best suited if you are looking for a targeted approach to gut health with fewer strains of probiotics and the included prebiotic.

It may also benefit you if you want to support healthy weight management.

Whether you wish to enter into a subscription or not, you may appreciate Bioma’s flexible purchasing options and affordable pricing.

Seed

Seed may suit your needs if you are seeking a comprehensive, research-backed approach to gut and overall well-being.

Its impressive diversity of 24 strains, combined with its commitment to transparency, makes it an attractive option if you desire the assurance of third-party testing and the peace of mind of knowing it meets strict manufacturing standards.

If you prioritize quality, traceability, and environmental responsibility, Seed's emphasis on scientific validation and its sleek, eco-conscious packaging may resonate with you.

Customer reviews and satisfaction

Here, we share what we learned about the products from feedback of actual customers.

What people say about Bioma

Official Website	Amazon	Trustpilot
No rating	3.6 out of 5 stars	3.4 out of 5 stars

Bioma has a 3.6 out of 5-star review on Amazon.

Several customers report feeling less hungry and experiencing weight loss. Some also say they are less bloated and have better bowel movements.

Some negative comments center around common probiotic side effects, including increased bloating, changes in bowel movements, and stomach cramps. Several also reported that the bottle arrived broken in the mail and that they had trouble getting their money back.

On Trustpilot, Bioma has a 3.4 out of five-star review. Positive comments revolve around many people experiencing better digestion. Negative comments have to do with difficulty terminating the subscription and confusion over the return policy.

While there is no overall rating, customers on the Bioma Health website report that they feel healthier and experience less bloating while taking the probiotic.

What people say about Seed

Official website	Amazon	Trustpilot
No testimonials or ratings	3.9 out of 5 stars	2.1 out of 5 stars

Seed has an Amazon rating of 3.9 out of 5 stars.

Customers appreciate the ease of only taking two capsules once a day, and many report improved digestion and less bloating. Several people comment that this is the best probiotic they've ever taken.

However, some report initial side effects after starting the probiotic, such as increased gas, cramping, bloating, and urgent bowel movements. Several also report feeling somewhat nauseous after taking it.

Several customers also complain about the price being too much.

On Trustpilot, Seed has a 2.1-star out of 5-star rating. Several people gave positive reviews about feeling better digestion and being able to use the restroom regularly.

Unfortunately, several of the lower ratings were not related to the Seed probiotic. Those that were, complained about being charged for a subscription they didn’t sign up for, not seeing results, or not being able to terminate the subscription.

We were disappointed to not find any customer reviews on Seed’s website.

Final verdict

Bioma provides a probiotic blend of three Bifidobacterium strains and added prebiotics. It also offers several purchasing options, which may be appealing to individuals who are budget-conscious.

Seed, on the other hand, offers 24 scientifically backed probiotic strains with a non-fermenting prebiotic. It targets more than digestive health by supporting cardiac and skin health. However, it does have a higher price point.

Ultimately, the choice of which probiotic is best for your gut health depends on your personal preferences, needs, priorities, and budget.

Keep in mind that it’s best to consult with your healthcare provider to determine if a probiotic is appropriate for your health goals and which one fits your needs.

Comparing Bioma and Seed with other probiotics

Probiotic	Strain diversity	Price	Best for...	Review
Bioma	9 billion CFUs of three Bifidobacterium strains	$25.99–69.99 per bottle depending on package	Those looking a probiotic that fits their budget	Bioma review
Seed	53.6 billion AFU24 probiotic strains	$49.99 per 30-day supply	Those looking support gut, skin, and cardiac health	Seed review
VSL#3	12.5 billion to 900 billion CFUs of eight probiotic strains	$65.95–157.95	Those looking to manage IBS and ulcerative colitis	VSL#3 review
Unbloat	25 billion CFUs of seven bacterial strains	$37.33 for a one-time purchase	Those struggling with bloating	Unbloat review
Ritual	11 billion CFUs of two bacterial strains	$54.00	Those looking for a prebiotic, probiotic, and postbiotic combination	Ritual review